Barely Significant

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Cox Proportional Hazards Models When the imaging biomarkers were analyzed independently in separate univariate models for overall survival ( Table 2 ) in Cohort 1, we noted statistically significant associations with tumor volume (HR = 2.59; 95% CI 1.06–6.29) and convexity (HR = 0.34; 95% CI 0.14–0.82), and a borderline significant association with entropy ratio (HR = 2.19; 95% CI 0.94–5.08).
3A ): (1) The amount of Gammaproteobacteria in controls maintained the same predominance for 9 days before NEC onset, yet it is significantly higher in controls than in NEC samples at 7–9 and 4–6 days prior to NEC onset (p = 0.01 and 0.008, respectively), and not significantly different just before disease onset as a result of Gammaproteobacteria from NEC cases showing an increasing trend while approaching disease.