Barely Significant

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Applying a Bonferroni correction for multiple tests resulted in significance drop to trend level for problems or symptoms, and to become non-significant for wellbeing—but significance levels remained highly significant for the other variables, including global distress, which is a compound of the other factors, and which was tested first.
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In addition, antibiotic-resistant serotype 19A emerged as replacement disease following the introduction of the first-generation pneumococcal conjugate vaccine (PCV7) in early 2000s, and became highly significant in the epidemiology of pneumococcal infections until immunization with PCV13 greatly reduced its prevalence [ 32 ].
Counts of prokaryotic cells using SEM imaging, showed a decreasing trend of cell density in the more landward-adapted species ( Fig 5 ). qPCR analysis ( Fig 6 ) corroborates (i) the SEM counting indicating that most of the prokaryotic cells imaged by SEM may belong to the bacteria Domain, and (ii) the significant decrease of bacterial numbers toward the supratidal species.