Thus, we selected only the triplets with highly significant (28 out of 125, p-value < 1.00E-04) non-zero values, summarising them in Supplementary Table S6 B.
Excerpts
As expected, AL dose-dependently decreased the total number of TRAP + h-OCs, resulting into highly significant inhibition at all the concentrations tested (p < 0.0001 vs control sample) (Fig. 3C ).
A quantitative analysis on day seven revealed highly significant differences in the number, size and roundness of the spheroids generated by D5 cells compared to control NIH3T3 cells ( p < 0.0001) (Fig. 3 b).
This quantitative analysis revealed highly significant overall differences between groups and sample areas (Group: F (1,40) = 38.89; p < 0.0001; Area: F (3,40) = 7.9; p = 0.0003; Interaction: F (3,40) = 3.2; p = 0.0332).
Statistical analysis via two-way ANOVA followed by Dunnett’s multiple comparisons test confirmed the significance of these observations ( P < 0.05), with highly significant differences (**** P < 0.0001) between controls and bacterial treatments in arsenate conditions.
This regression was highly significant (standardized beta = 0.49 ± 0.002, t = 35.25, P < 0.0001, R 2 = 0.34; linear regression).
Statistical analysis revealed highly significant linear and quadratic effects for all metrics ( P = 0.0001, indicating a complex relationship between selenium dose and growth, with potential for an optimal selenium level.
These results yielded highly significant class distinction between NEC and Sepsis (AUC = 0.958; p < 0.0001 ) ( Fig. 2C ) as well as NEC and control (AUC = 0.91; p < 0.0001 ) ( Supplemental Fig. 3 ).
Linear regression analysis showed a highly significant correlation between hemispheric loss and hippocampal area loss (R2 = 0.855, p < 0.0001), with hippocampal loss tending to be greater (B = 1.209) than hemispheric area loss.
A highly significant positive trend in hatchability was observed for the brown layer line ( P = 0.0001), with hatching rates increasing from 52% at ED4 to 87% at ED7.
pombe spores irradiated at the same level; the differences being highly significant (p < 0.0001) ( Fig. 1B ).
Results showed the most effective binary combinations against MRSA, excluding β 14 (SGEO-TET) and β 34 (SMEO-TET), while the ternary combination of VOEO, SMEO, and TET ( β 234 ) had a highly significant effect on SACI-1 ( p = 0.0001).
The PRF/Exosome group continued a steady decline after T6, with the first significant reduction below T0 occurring at T10 ( P = 0.0493) and a highly significant decrease by T12 ( P < 0.0001).
All inter-device correlations elicited a highly significant correlation with r-values of 0.72–0.86 (all p < 0.0001, Table 2 , Supplemental Figure S4).
At 38 °C a similar pattern emerged; the overall predator effect was highly significant (ANOVA on the binomial generalized linear model, effect of predator treatment: LR χ 2 = 26.30, d.f. = 2, P < 0.0001; Fig. 2a ), but that was only attributable to lycosids, which caused the highest mortality, significantly different from control and pisaurid effect (contrasts: lycosid-control: z = 3.73, P = 0.0005; pisaurid-lycosid: z = −2.75, P = 0.01).
A generalized additive model (GAM) fitted to the normalized data revealed strong non-linear temporal structure in activity under all light treatments, with highly significant treatment-specific smooths of time (all F > 380, all p < 0.0001), explaining 97.6% of the variance in normalised activity (adjusted R 2 = 0.97).
In individual comparisons, the correlation value ranged from 0.85 to 0.98 and was highly significant in all the cases (P-value < 0.0001).
In the absence of BPs, vWF expression by the endothelial growth media stimulated pMSCs showed an increasing trend over the experimental period with a significant 4-fold up-regulation (p < 0.0001) in expression at the end of ten days.
A highly significant decrease ( P value = 0.0001) in the expressions of miRNA-106a and miRNA-20a was reported in COVID-19 patients compared to controls.
The model, as well as the parameters in the model, were extremely significant (P < 0.0001).
Furthermore, in all four regions, pairwise comparisons (Dunn’s test) of the frequency distributions of TBA values among locations with defoliation, mortality, or no damage showed highly significant ( p < 0.0001) differences between the three groups (Fig. 5 , Table 2 ).
At higher concentrations (12.5–50 μg/mL), the extract exhibited pronounced inhibitory activity, with highly significant reductions in biofilm biomass compared to the control group (*** p < 0.0001).
There was a highly significant relationship of each morphometric variable with FL ( R 2 = 0.65–0.97 , p < 0.0001).
The mean age at death for animals unaffected was 614 days (SEM ± 20) compared to 741 days (SEM ± 18) for animals with pathology; a difference which is highly significant ( p < 0.0001, two-tailed unpaired t test).
A highly significant interaction between treatments and the cut number was noted (P < 0.0001).