Excerpts

In recent years, there is also an increasing trend to apply proteomics in zebrafish for developmental analyses, disease studies and assessments of chemical toxicity.

Both changes in the expression level were highly significant ( p -values 2.5 × 10 −6 and 4.9 × 10 −6 ).

The PMCH gene is not detected significant in the ordinary regression (P-value: 0.429), but is detected highly significant in the robust regression (0.022).

The increasing trend of summer and winter precipitation over the Himalaya is associated with an increasing trend in precipitation extremes connected to the changing pattern of the summer monsoons 20 , 24 , 25 , 26 , 27 , and an enhancement in the strength and frequency of winter westerly disturbances 18 , 28 , 29 , 30 , 31 (extratropical storms driven by the Westerlies, that bring sudden winter rain and snow to the northwestern parts of the Indian subcontinent), respectively.

The activation profile of the different OSNs revealed a highly significant activation in response to food odor compared to controls in ciliated and microvillous OSNs (cOSNs, mOSNs) ( Fig. 3a,b ).

The calculated R ′ showed a decreasing trend with depth for both Fe and P, reflecting that the capacity of the sediment solids to sustain the pore water Fe or P became weaker with depth.

There was an increasing trend with depth down to the sediment bottom at Sites 3, 7, 8, 10, 11, 14, 15 and 16 for both Fe and P, and at Site 5 for Fe.

And a clear trend of antifouling capability is revealed as GO-P-S membrane >P membrane >GO-P membrane.

A clear trend which was already found and discussed by Miyake et al. 7 is the strong increase in K 1 when going from 1–12 to 1–12-X phases.

2 ), performed with the REDFIT method, reveals a significant periodicity at 208 years and marginally significant periodicities at 83, 31, 18–16, 11, 9 and 7–3 years ( Fig. 2 , Supplementary Fig.

Nevertheless, the median lines and the Inter-Quartile Ranges (IQRs) clearly suggest a decreasing trend with a high confidence.

When the calculation is segregated by exposed or not exposed (at home) values show a slight trend towards higher values of the ratio for exposed individuals ( Table 2 ).

When considering species turnover against geographic distance between sampling locations, patterns of turnover with distance were highly significant for tea-forests and tea than for rubber-forests and rubber across arthropod groups ( Table 4 ).

Despite the non-perfect uniformity of target molecule adsorption over the whole sensor surface, a definite trend of Raman signal enhancement with protein concentration can be identified.

We found a reduced expression of miR-135b levels in SSc compared to control fibroblasts, however, this did not quite reach statistical significance ( Fig. 4B ).

Patients without ascites showed a trend towards a lower prevalence of diabetes than those with ascites and they were more frequently receiving treatment with beta-blockers or proton pump inhibitors.

The diabetic tissues showed a trend toward reduced sensitivity to the inhibitory effect of the c-kit antagonist imatinib on phasic contractions 18 .

Still to be addressed are the physicochemical and pharmacokinetic aspects of PGH treatments [which are likely to be significant, considering the potential for intracellular transport].

Moreover, we observed a negative trend for the ultimate strain versus time, attesting a general decrement of the resistance force.

We detected a positive trend versus time for the Young’s modulus, indicating that aged silks are stiffer and possibly less effective in catching prey.

Kaplan-Meier survival curves revealed a significant trend towards poorer survival for patients whose primary tumors showed low 14-3-3σ expression, compared with those patients whose primary tumors showed high 14-3-3σ expression (Log Rank = 16.351, P = 0.000; Fig. 4D ).

The results indicated that after the first two stimulations, there is a decreasing trend in the proportion of good responders and in the number of oocytes retrieved with increasing times of ovarian stimulations.

A clear trend was apparent among amino acid residues having aliphatic and aromatic side chains ( Table 4 ).

Separate from tests for gene-environment interactions, time spent outdoors itself was not associated with myopia in 3 of the 5 cross-sectional studies (GZT, STARS, and TEDS) and the association was of borderline significance in another (TEDS).

However, for attempted suicide, we identified depression, but not anxiety, to be a marginally significant factor.