Excerpts

Compared to the first reference year (2009), except ethylbenzene, o-xylene and temperature, in the last years a decreasing trend can be observed in the annual mean concentrations.

A post-hoc analysis of a randomized control trial showed a trend towards improved outcomes with lower target glucose control compared with conventional control in patients with A1C < 5.0%, even though hypoglycemia was more prevalent (adjusted hazard ratio 0.60, 95% CI 0.35–1.01; P = 0.052).

On the other hand, the association between a TIR of absolute normoglycemia > 80% and mortality was almost significantly dependent on A1C levels.

Low serum Hb levels (AUC, 0.75; sensitivity, 75.0%; specificity, 70.6%; P = 0.003) and high βhCG levels (AUC, 0.73; sensitivity, 68.8%; specificity, 67.6%; P = 0.001) were identified to be highly significant predictive factors for massive hemorrhage.

The SAT response to ALL forcings clearly shows a positive trend throughout EA during the study period, with an increase of approximately 0.031 °C/decade between 1850 and 2014 (Period 1 = P1) and 0.255 °C/decade between 1971 and 2014 (P2).

The time and molar ratio had a direct effect on the reaction efficiency and increasing their values was an increasing trend.

In this case, p < 0.05 was considered statistically significant, and p < 0.0001 was considered highly significant.

Not surprisingly, when applying the 484 commonly upregulated, lung function decrease-associated genes to EnrichR pathway analysis, highly significant enrichment of ECM, focal adhesion, EMT and Wnt signaling associated processes was found (Fig. 4 b).

Air temperature had a highly significant positive effect on water temperature with a regression coefficient twice as big in the monthly compared to the daily model (Table 2 ).

At the reach scale, the cooling effect of riparian cover became weaker with increasing timescale, its effect size halved and shifting from highly significant to marginally non-significant in the monthly model (Table 2 ); its relative importance reduced from 23.52 to 16.93% (Fig. 2 a-b).

On the other hand, older extrusive volcanic rocks often experience a decreasing trend in porosity and hydraulic conductivity with increasing geological age resulting from the filling of vesicles and fractures by secondary material.

The differences between grass and legumes for CP contents are quite significant; hence a blend of grass and legume in ruminant diet is more recommendable 34 , 46 .

For example, APP/PS1 mice show an overall trend towards reduced power in the lower frequencies (delta and theta) and higher power in the faster frequencies (alpha and beta) 47 .

However, especially the impact of textured surfaces like solar cell substrates might be significant.

To test whether there might be significant differences between eUBs and ex-fetu UBs, we performed RNA sequencing.

2 , precipitation, rainfall and snow show an increasing trend, but the increase range of snow (0.0325–0.375/a) is significantly lower than that of precipitation (1.22–3.1/a) and rainfall (1.04–2.81/a).

The variables of respondents’ education level were highly significant ( P value 0.01, coefficient 0.023).

Figure 1 showed a trend in the association between sALB and the risk of MACE (logHR), indicating that the risk of MACE decreased as the baseline sALB increased.

The expression of SOD1, PRDX5, and GPX4 was significantly increased in the lesion; while the level of HO-1 had an increasing trend, it was not significant (Fig. 4 A–J).

However it presents a small trend to the left and still performs turns around the y axis.

The geographical distribution of 25(OH)D values of healthy elderly in China showed a trend of being higher in South China and lower in North China, and higher in coastal areas and lower in inland areas.

Although an increasing trend for the amount of compounds extracted from the seeds was observed from 60 to 100 °C, no significant differences between the amount of compounds from the extracts were observed between the four different extraction temperatures (Fig. 1 ).

This revealed a highly significant difference of ITV between groups ( F ( 1 , 206 ) = 82.35 , p = 4.38 · 10 - 12 , η 2 = 0.21 ).

The stiffness of the C22 phage showed a decreasing trend as the temperature increased (Fig. 4 ).

On the other hand, the daily increase in COVID-19 cases can be modeled as a random walk due to the complex nature of human interactions and it has an overall trend as an infectious disease in the spread and controlled phases.