Excerpts

Daily dosage and duration of metformin are not related to the magnitude of reduction in serum testosterone levels, and reduction in serum testosterone levels from metformin was classified into two categories 25 ; in non-obese women, metformin significantly reduced serum testosterone levels, whereas it resulted in only marginally significant reduction in obese women.

The correlation between gastric mucus IgA and peripheral IgA is positive and highly significant, ranging from 0.618 to 0.779 40 , 41 .

Highly significant phenotypic associations were observed among the traits and across years (Table 2 ).

The pH factor was dropped because it was not significant in presence of the other factors in the equation, thus the final model has the following form 8 p r e d i c t e d q e = 20.41 + 0.16 C 0 + 0.15 t − 13 l n ( d o s e ) + 2.5 X The model developed after dropping the pH is highly significant with a p -value of 1.074e-15.

Estimation of variability parameters The ANOVA revealed that there is highly significant differences existed among the breeding lines considering the agro-morphological traits (Supplementary Tables S1 – S5 ).

The differences were always highly significant regardless of the method of statistical analysis (Table 4 ).

They were the lowest for HDL-P or total and cardiovascular mortality (HR = 0.60 [95% CI, 0.46–0.79] and HR = 0.63 [95% CI, 0.46–0.86], respectively) and the highest and at the limit of significance for HDL-C (HR = 0.71 [95% CI, 0.55–0.92] and HR = 0.72 [95% CI, 0.53–0.99] respectively).

The ITS analysis of CDI incidence showed a decreasing trend in both the intervention phases.

Many studies showed an increasing trend of myopia incidence as we are approaching the era of modern industrialization along with increasing education level 3 , 11 , 19 , 20 .

The results presented here are quite significant as we have found that surface concentration increases as the pH is raised contrary to most of the earlier studies 21 .

A highly significant difference was observed between the slopes of the recovery of axial length between myopic and hyperopic defocus conditions during 20 minutes of clear vision (slope ß, myopic = 0.109 vs hyperopic defocus = −0.313, p < 0.001).

The rate of paint removal shows an increasing trend as the particle size decreases.

There was a decreasing trend in soil EC and nitrate content with decreasing fertilizer rates.

There was a slight trend towards more INT/IINHT if only a cervical non-balloon-guide catheter was used instead of a balloon-guide catheter and/or a distal access catheter.

This analysis used all of the SNP data not just the outliers, and a highly significant correlation (r = 0.93) between PC1 and longitude of the collection sites was found (Supplementary Fig.

In a recent large meta-analysis of studies investigating gait and balance, arm motor function and movement planning, a large and highly significant overall effect size was found showing gross motor impairments in autistic individuals in all examined domains 8 .

For class Anthozoa at the genus level, we noted an increasing trend in the proportion of sequences with anthropogenic pressure for Anthopleura (speciose genus of sea anemones), Palythoa (sand-encrusted colonial anemone), and Zoanthus (non-sand-encrusted colonial anemone).

Although there is a decreasing trend in streamflow in both future time periods, in general, there are no much differences among the three RCPs.

For the second period (2005–2016), the same regions did not show signs of hard coral recovery; and as in the rest of the regions, macroalgae cover continued on an increasing trend (Fig. 5B ).

However, the average hard coral mean effect size of ARC for the Northern, Center, and Southern regions were all positive thus supporting the mean effect size for ARC for the overall MC towards a positive trend (2005-2016; Fig. 5A ).

The Center and South regions experienced the greatest rates of hard coral cover decline and highly significant increases of macroalgae cover between 1978 and 2004.

In contrast, in healthy controls, a highly significant correlation between iHGP and VWM scores occurred in the left STGp during the second syllable encoding, consistent with the correlation observed in controls with auditory working memory task performance ( r = 0.82, p = 0.0002).

6 , confirming an increasing trend similar to that observed for lower concentrations of Fig. 4 also in this case.

Except at the seedling and tillering stages of rice, soil alkaline N and urease activity had a highly significant positive correlation.

There has been an increasing trend towards multiband and multifunctional polarization conversion devices 7 – 9 so that multiple systems may be merged and subsequently efficient miniaturization may be achieved.