A highly significant main effect of interactive prompt type was identified for both retention scores, F(1,228) = 163.715, p < 0.001, η 2 = 0.395, MSE = 40.48, and transfer scores, F(1,228) = 944.070, p < 0.001, η 2 = 0.679, MSE = 8.12, indicating that the 3D interactive condition yielded substantially higher learning outcomes than the conventional interactive condition.
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While a uniform main effect of exercise on sEMG amplitude (RMS, MAV) was not observed, the analysis revealed robust and highly significant exercise × muscle interactions ( p < 0.001 for both RMS and MAV), consistent with prior evidence that exercise effects on sEMG are muscle-specific [ 37 ].
The level of plasma homocysteine (Hcy) in patients with MTHFR CC, CT and TT genotypes showed an increasing trend ( P < 0.001).
Statistical analysis revealed highly significant differences between the periods (p < 0.001), as shown in Supplementary Table S2 .
The log-rank also reported a highly significant association between survival and ferritin values with P < 0.001.
The equation was highly significant [ F (7,95) = 16.53, p < 0.001], representing a large effect size, f 2 = 1.14.
On applying t -test for two independent groups, the mean difference of width of intracanal dentinal tubule openings (−2.2726400 μm) was highly significant ( P < 0.001).
The one-way ANOVA model confirmed highly significant between-group variation (F = 28.7, p < 0.001), with the transitional phase accounting for 63% of the total variance.
A highly significant group × BMI interaction was observed for MECPP, MEP and BPS (B = 0.14, p < 0.001; B = 0.32, p < 0.001; B = 0.34, p < 0.001, respectively), indicating that the effect of BMI on their levels reversed direction between groups.
The statistical value of * P < 0.05 is considered as significant difference; ** P < 0.01 is considered as extremely significant difference; *** P < 0.001 is considered as very significant difference.
Additionally, the mean total charges revealed an increasing trend, from $230,581 for 1 bed to $248,294 for 2 beds and $236,975 for ≥3 beds (p < 0.001).
Specifically, CBL exhibited a positive and moderately significant direct effect on OC (β = 0.584, se = 0.058, p < .001), confirming Hypothesis 3.
The mean difference was − 2.87 (95% CI: -3.76 to -1.98), also highly significant ( p < 0.001).
The Spearman correlation was highly significant (ρ = 0.915, p < 0.001; Supplementary Figure S9, left panel), which validates that SHAP can accurately capture feature importance in linear models.
In contrast, stage II–IV patients displayed persistent, highly significant OS benefits (all P < 0.001), consistent with a systematic review from the Cancer Care Ontario Program [ 24 ].
The spatial smoother for longitude and latitude was highly significant ( p < 0.001), suggesting residual spatial heterogeneity not fully explained by the included predictors. 3.2.
BAKHF administration achieved highly significant reversals across all tested markers ( P < .001), successfully driving the expression levels of CD31, VWF, ET-1, collagen I, and α-SMA back to baseline levels that were not significantly different from those of the NC group ( P > .05).
Many of these pairings were found to be highly significant with p < 0.001, suggesting a significant difference in HD between the age and diet groups.
Current pain intensity was not considered in the following analyses, because correlation analyses revealed highly significant positive correlations between current global pain-induced disability and current pain intensity, such as current dysmenorrhea (ρ = 0.464; p < 0.001), non-cyclic pain (ρ = 0.472; p < 0.001), dyspareunia (ρ = 0.354; p < 0.001), dysuria (ρ = 0.405; p < 0.001), dyschezia (ρ = 0.477; p < 0.001), lower back pain (ρ = 0.446; p < 0.001), and global pain intensity (ρ = 0.604; p < 0.001).
[3] Highly significant correlation was found between conventional and digital radiograph for alveolar bone level measurements (p<0.001).
The seven-year PV of Clostridium butyricum , Bacillus mesentericus , and Enterococcus faecalis was 10.9% with a decreasing trend (Z = -4.40, p < 0.001).
Among these, PS exhibited the strongest discriminative performance, with highly significant differences between csPCa and ciPCa in the overall, PZ, TZ, and ≥1 cm lesions (all P<0.001).
Thus, the correlation between IMD (as IMD rank score) and the global Broadband Digital Deprivation Index was tight and highly significant (r=0.902, p<0.001).
Model for deaths The median age, prevalence of obesity among adults, population density, GDP per capita, and dependency ratio were positive and highly significant ( p < 0.001), suggesting a strong association with dengue fatality.
Table 2 shows a highly significant (p<0.001) difference in the distribution of post-operative complications according to the Clavien-Dindo classification, with a greater percentage seen among obese patients who developed grade 2 (41.7%) and grade 4 (37.5%) complications.