Barely Significant

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highly significantP < 0.0010.0× alphaqualifiedgold
The changes of tolerability between both groups were highly significant ( P < 0.001), thus indicating that tolerability was significantly better following a 7-day treatment with ectoine containing nasal spray in comparison to 7-day treatment with cromoglycic acid nasal spray.
highly significantp < 0.0010.0× alphaqualifiedgold
In contrast, when the model considered all available PTX3 readouts which, for patients who developed GvHD, included the measurement at onset, it revealed that PTX3 had indeed a highly significant diagnostic relevance ( p < 0.001), suggesting that the protein level rose at time of GvHD occurrence.
highly significantP < 0.0010.0× alphaqualifiedgold
When adverse events were evaluated for the worst toxicity encountered during treatment, there was little difference between the groups, but when they were assessed per cycle, alternating treatment was associated with fewer severe (grade 3 or 4) adverse effects ( P = 0.013), and the difference was highly significant for cycles when gemcitabine was administered in group D/G ( P < 0.001).
highly significantP < 0.0010.0× alphaqualifiedgold
On statistical comparison between initial stage and different follow-ups, no significant outcome was seen from first follow-up ( P > 0.05) in intensity and duration of pain but comparison between initial stage and different follow-ups showed highly significant results in the second follow-up ( P < 0.001) with regard to all the symptoms, except diarrhea, backache and pain in vagina.
highly significantp < 0.0010.0× alphaqualifiedgold
Complementing this, Bartlett’s test of sphericity was highly significant (χ 2 = 3709.485, df = 435, p < 0.001), confirming that the correlation matrix is not an identity matrix and that substantial relationships exist among items.
highly significantp < 0.0010.0× alphaqualifiedgold
In a selected group of 50 cases with typical spongiform change and mild to moderate neuronal loss, we found a highly significant positive correlation between the amount of this prion-specific tau deposition and p-tau levels in the CSF ( r = 0.564, p < 0.001; n = 50) (Fig. 6 a).
highly significantP <.0010.0× alphaqualifiedgold
Findings of this study include a significant decrease of the patients’ pain sensation over time ( P =.006), a low but highly significant correlation between pain sensation and steps taken on the same day ( r =−0.11; P <.001) and the walking distance of the independently performed 6MWTs ( r =−0.39; P <.001).
extremely significantP < 0.0010.0× alphaqualified
The best effective group was a combination of curcumin 50 mg/kg with piperine 20 mg/kg which showed extremely significant ( P < 0.001) decrease and increase in ECG and serum biomarker level, respectively, and moderate significant ( P < 0.01) decrease in lipid profile, antioxidant levels, and histopathological score, compared to curcumin alone-treated group.
highly significantp < 0.0010.0× alphaqualifiedgold
high in trait impulsivity, based on median score on BIS-11) × 4 (four time points during cue exposure) repeated-measures ANOVA showed again a marginally significant main effect of drinking status ( F [1, 38] = 4.02, p = 0.052) and a highly significant main effect of cue exposure ( F [1.72, 65.18] = 16.33, p < 0.001) on craving.