The changes of tolerability between both groups were highly significant ( P < 0.001), thus indicating that tolerability was significantly better following a 7-day treatment with ectoine containing nasal spray in comparison to 7-day treatment with cromoglycic acid nasal spray.
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In contrast, when the model considered all available PTX3 readouts which, for patients who developed GvHD, included the measurement at onset, it revealed that PTX3 had indeed a highly significant diagnostic relevance ( p < 0.001), suggesting that the protein level rose at time of GvHD occurrence.
These differences were found to be highly significant (p < 0.001) using the Chi square test.
There was no significant activity of these enzymes between the intergroup. In Table 5 , latent MMP-9 showed highly significant activities among women who experienced their first menarche ≥ 14 when compared between tumor and normal tissue specimens (P<0.001).
Pearson's correlation analysis between social participation and CES‐D showed a highly significant positive correlation ( r = 0.377, p < 0.001), indicating that depression increased with an increase in social participation difficulty.
When adverse events were evaluated for the worst toxicity encountered during treatment, there was little difference between the groups, but when they were assessed per cycle, alternating treatment was associated with fewer severe (grade 3 or 4) adverse effects ( P = 0.013), and the difference was highly significant for cycles when gemcitabine was administered in group D/G ( P < 0.001).
A statistically highly significant difference (p≤0.001) compared to 0 h p.i. was first detected after 8 h in S2 cells and after 24 h in Sf9 cells.
On statistical comparison between initial stage and different follow-ups, no significant outcome was seen from first follow-up ( P > 0.05) in intensity and duration of pain but comparison between initial stage and different follow-ups showed highly significant results in the second follow-up ( P < 0.001) with regard to all the symptoms, except diarrhea, backache and pain in vagina.
The effect of temperature was highly significant with lower temperature resulting in higher adult L. bostrychophila counts (t = −5.763, p<0.001).
Dance activities before the accident happened Highly significant gender differences (p<0.001) (Figure 2 ) were observed with movement contents where explicitly named jumps ( allegro , grand allegro, cabriole, grand jeté ) resulted in the most frequent traumatic injuries in males (sprains, pulled muscles).
There was significant variation in knowledge gain among courses (SD 1.50, p = 0.031) and highly significant variation among learners within courses (SD 2.14, p < 0.001).
Complementing this, Bartlett’s test of sphericity was highly significant (χ 2 = 3709.485, df = 435, p < 0.001), confirming that the correlation matrix is not an identity matrix and that substantial relationships exist among items.
assigned as 0.165 CFU/plate) confirmed a highly significant main effect for the phage treatment (F(1, 20) = 8813.48, p < 0.001).
In a selected group of 50 cases with typical spongiform change and mild to moderate neuronal loss, we found a highly significant positive correlation between the amount of this prion-specific tau deposition and p-tau levels in the CSF ( r = 0.564, p < 0.001; n = 50) (Fig. 6 a).
The overall model was highly significant (χ 2 = 26.8, df = 2, p < 0.001) and demonstrated excellent calibration (Hosmer–Lemeshow p = 0.99).
Findings of this study include a significant decrease of the patients’ pain sensation over time ( P =.006), a low but highly significant correlation between pain sensation and steps taken on the same day ( r =−0.11; P <.001) and the walking distance of the independently performed 6MWTs ( r =−0.39; P <.001).
96.67%) proved to be highly significant (χ 2 =30.06; df =1; P <0.001).
The significance level was defined as follows: p ≥ 0.05 not significant, p < 0.05 significant, p < 0.01 highly significant and p < 0.001 most highly significant.
Our brain–behavior correlation analyses implied multiple testing (25 tests), and therefore only highly significant findings ( P < 0.001) reported in Table 3 correspond to significance after multiple comparison correction (Bonferroni).
This increase was significant at 20 μg/mL after 6 h of exposure (* /# p < 0.05) and highly significant at 20 μg/mL after 12 h of treatment (* p ≤ 0.001; # p < 0.01).
The best effective group was a combination of curcumin 50 mg/kg with piperine 20 mg/kg which showed extremely significant ( P < 0.001) decrease and increase in ECG and serum biomarker level, respectively, and moderate significant ( P < 0.01) decrease in lipid profile, antioxidant levels, and histopathological score, compared to curcumin alone-treated group.
Statistical significance was denoted as follows: *( p < 0.05) represented statistically significant; **( p < 0.01) represented highly significant; ***( p < 0.001) represented extremely significant; ( p > 0.05), ns represented no statistically significant. 3.
However, a highly significant ( P < 0.001) antinociceptive effect was observed at 150 mg/kg (83.02 %).
In addition, Bartlett’s Test of Sphericity yielded a highly significant result (χ2 = 7238.63, df = 3321, p < 0.001), confirming that the observed correlation matrix was not an identity matrix and thus appropriate for structure detection via EFA (Table 2 ).
high in trait impulsivity, based on median score on BIS-11) × 4 (four time points during cue exposure) repeated-measures ANOVA showed again a marginally significant main effect of drinking status ( F [1, 38] = 4.02, p = 0.052) and a highly significant main effect of cue exposure ( F [1.72, 65.18] = 16.33, p < 0.001) on craving.