Barely Significant

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highly significantp < 0.0010.0× alphaqualifiedgold
New: Figure 2 Kidney function using a) creatinine and b) GFR as surrogates during the follow-up period of 60 months (black HC, grey nESPC) HC = historic cohort, nESPC = new European Senior Program cohort, *** highly significant, p < 0.001 Data are presented as mean ± standard deviation.
highly significantP < 0.0010.0× alphaqualifiedgold
The permuted multivariate analysis of variance (perMANOVA) with Aitchison distances to test the effect of the agricultural practices indicated a large and highly significant effect on the bacterial community that explained 45% of the total variance ( P < 0.001, Table 2 ).
highly significantp < 0.0010.0× alphaqualifiedgold
Intragroup comparisons revealed significant improvement in the control group ( p = 0.024) and a highly significant improvement in the treatment group ( p < 0.001), indicating that the combined regimen achieved a more pronounced and clinically meaningful effect ( Table 2 ) 3.3 Survival analysis During the 6-month follow-up period, survival rates showed a gradual decline in both groups; however, the treatment group consistently demonstrated significantly higher survival rates than the control group at all predefined assessment time points (30, 90, and 180 days).
highly significantp < 0.0010.0× alphaqualifiedgold
Highly significant differences in VK2 serum concentrations between controls and MS patients were found ( p < 0.001) with controls showing more than three-fold higher levels on average.
Vitamin K2 in multiple sclerosis patients.
Wien Klin Wochenschr · 2018 · PMC5966473
highly significantp < 0.0010.0× alphaqualifiedgold
Differences between groups of *p < 0.05 were considered statistically significant, **p < 0.01 were considered highly significant, and ***p < 0.001 were considered very highly significant. 3 Results 3.1 Preparation and physicochemical characterization of the SIS/PDA/Cu bio-patch The preparation and surface modifications were illustrated in Fig. 1 a.
an increasing trendP < 0.0010.0× alphagold
However, post-2015 patients were more likely to be pathologic node-negative (69.8% vs 41.6%, P < 0.001) ( Table 1 ). National trends The Cochran–Armitage test showed that there was an increasing trend for lobectomy from 2004 to 2018 ( P < 0.001), with an overall increase from 11.6% in 2004–2015 to 18.9% in 2016–2018 ( P < 0.001).