Excerpts

Permutation testing reveals that skewing in the 19p region is highly significant (p<10 −11 ).

The overall differences between the incidences of the tested neuronal markers among the virus delivered eGFP expressing neurons were highly significant, the Kruskal Wallis H test between groups: Hdf = 61.2, p < 1e − 11.

Expanding the observation to cells that showed morphological changes, including elongation, that preceded divisions, another 87 cells appeared to be preparing for division in aggregates while none of the isolated cells showed any shape change, which was a highly significant difference (24.3% vs 0%, two-sided p< 10 - 11).

Highly significant differences were observed in the level of clustering, or transitivity ( F = 86, p = 10 −11 ), however, with the antigens showing strong clusters separated from each other.

The difference between slender and bulky populations that were not reshaped remained highly significant ( P < 10 −11 , Wilcoxon rank sum).

The most unexpected effect of Inosine showed highly significant increased expression of proteins in complement cascade (c1qa, c1qB, c1qy, c1, c2, c3, c4B, adipsin) with p < 10 -11 [ 50 ].

The usual care plus albendazole arm continued, however, to show a highly significant difference in weight gain (2.8 [SE 0.1] kg vs. 3.8 [SE 0.1] kg, difference 1.0 [SE 0.15] kg, p = 10 −11 ), with the dewormed children exhibiting a 35 (SE 5) % higher weight gain.

When we examine spontaneous avoiding reactions of freely swimming paramecia, we find that both backward swimming duration and reorientation angle vary broadly (156 ± 81 ms and 114 ± 66°, respectively) ( Fig 9H ), and there is a small although highly significant correlation (linear regression, r = 0.2, p = 10 −11 ).

A generalized linear regression model with output SRT benefit modeled just from avREOIG (i.e., SRT benefit ∼ 1+ avREOIG) showed both intercept ( p < 10 −22 ) and avREOIG ( p < 10 −11 ) to be highly significant factors with an overall r 2 = 0.371 ( p < 10 −11 ), that is, 37.1% explained variance.

In Mp toc1 ko mutants, expression of Mp PRR was continuously high and arrhythmic, as indicated by highly significant effects of both genotype (G) and genotype x time interaction (GxT) terms in ANOVA ( P < 10 −11 ), suggesting that MpTOC1 represses Mp PRR .

8 b) and had highly significant enrichment of interactions between them (STRING: expected number of edges: 5; number of edges: 28; PPI enrichment p-value: ****p < 1 × 10 –11 ) , while random samples of 43 peaks from either all GWAS ALS genes or from all epiChromALS peaks showed no functional enrichment, suggesting a mechanistic link between these genes, neuronal development/function, and epigenetic mechanisms.

Specifically, for ROC-AUC, the differences were highly significant versus ChemBERTa ( t = 11.99, p < 1 × 10 −11 ) and CLAMP ( t = 10.23, p < 1 × 10 −10 ).

The PWM score changes are highly significant between activating and repressing variants (one-sided Wilcoxon Rank Sum test, p -value < 10 −11 ).

The effect of set size was also highly significant [ F (2,54) = 73.84, p < 10 -11 , η p 2 = 0.73], showing that the Mooney face targets were not searched efficiently.

2, A and B ), which is not considered a statistically significant increase (P = 0.8) but is highly significant when compared with spontaneous breaks in WT and 53BP1 KO cells (P = 1.01 × 10 −11 for WT and P = 0.00016 for 53BP1 KO).

Independent-samples t-test revealed that MD patients ( n = 31) displayed significantly higher Delta_TP_C-B values (Mean = 0.383, SD = 0.104) compared to SV patients ( n = 19; Mean = 0.162, SD = 0.040), yielding a highly significant difference ( t = 8.89, p = 1.04 × 10 −11 ).

Differences were highly significant ( p < 1.05e-11, OR = 7.67; Fig. 2 C).

The positive association between San ancestry and TB susceptibility was highly significant, whereas association with Bantu ancestry was relatively weak (p-value =1.06×10 -11 and p-value =3.00×10 -2 respectively) [ 8 ].

Overall between-group differences were highly significant ( p = 1.113 × 10 −11 ; p _adjust = 2.226 × 10 −11 ) ( Figure 2 A).

Formal meta-analysis of the replication cohorts was highly significant (OR = 5.2, 95% CI = 3.2-8.5, P = 1.2 × 10 −11 ).

1 E), including a highly significant increase in the abundance of Staphylococcus genus after transplant (Fig. 1 E, ANCOM-BC, p = 1.2 −11 ).

Meta-analysis using the inverse-variance method within METAL[ 29 ] resulted in a highly significant associations with neuroblastoma ( Table 1 ; rs6441201: P = 1.21x10 -11 , Odds Ratio 1.23, 95% CI:1.16–1.31 and rs3796727: P = 126x10 -12 , Odds Ratio 1.30, 95% CI:1.21–1.40; rs3796725: P = 2.08 x 10 −11 , Odds Ratio 1.29, 95% CI:1.19–1.38). rs3796727 genotype correlates with methylation status of C

However, when only the time of the recovery activity was considered, we observed highly significant differences in the caloric consumption between groups ( p = 1.22 × 10 −11 ; Figure 3A ).

4 b, the Kaplan-Meier analyses exhibited highly significant differences in time to overall survival between two different risk groups (hazard ratio [HR], 16.4; 95% confidence interval [CI], 5.68–47.3; p = 1.263e-11).

In general, the Kruskal–Wallis test indicated a highly significant association between subcutaneous fat thickness and the occurrence of fractures, regardless the experimental group ( p = 1.29 × 10 –11 ). 3.3.