Excerpts

For Subfamily 5 (16 ALMT loci, OG0008930), the test detected highly significant positive selection on terminal Vaccinium branches ( Figure 4 A): 2ΔlnL = 40.65 (df = 1; raw mixture-distribution p = 9.1 × 10 −11 ; Bonferroni-adjusted p = 2.7 × 10 −10 ), with the alternative model recovering a foreground ω 2 ≈ 34.95 in 5.6% of sites.

The weight of PbA-C57BL/6 mice started to decrease significantly on day 6 post infection and was the lowest on day 8 both in groups A (− 0.08 ± 0.05% decrease) and B (− 0.08 ± 0.02% decrease), when there was a highly significant difference between the PbA-infected group and the uninfected control group ( p = 9.27 × 10 −11 , Student’s t test) (Fig. 2 a).

The regression model was highly significant (F = 33,119.09, p = 9.51 × 10− 11 ), with slope of 1.0150 (95% CI 1.0007–1.0293) and intercept of 1.0626 (95% CI 1.0327–1.0924), confirming statistical significance of both parameters.

Second, our study had excellent statistical power, yielding highly significant MR associations for IFNAR2 ( P =9.8×10 -11 ), increasing confidence in the validity of the much weaker signals for IFNAR2 reported in the GenOMICC study ( P =0.004), particularly as the earlier report had displayed evidence of confounding by LD ( P HEIDI = 0.015). 37 Indeed, compared to the analysi

The differences are highly significant (TT mean – TM mean: P = 9.99E − 11 ; TT mean – TM median: P = 0.0013, KS-test, two-sided, α = 0.05).

Notably, magnesium, potassium, Folate, and vitamins A, C and E demonstrated highly significant associations with Prudent dietary adherence ( p < 1 × 10− 10 ), consistent with their known roles in oxidative stress, inflammation, and vascular health [ 67 ].

In these studies, a highly significant ( P <1×10 −10 ) association was detected for CDKAL1 , in accordance with the present study in Japanese.

The darkred gene module had a highly significant correlation between GS and MM with respect to both CVH metrics ( r = 0.39, p -value = 1.0 × 10 −10 ) and BDI-II score ( r = 0.62, p -value = 1.4 × 10 −28 ) ( Figure 3 ). 3.5.

1 B, were 0.45 ± 0.13 (standard deviation) and 0.92 ± 0.07, respectively; the difference was highly significant (P < 10 −10 , t test for paired measurements).

The logistic regression and Cox models adjusted for tumour size were also consistent with a highly significant difference between the two groups ( P <10 −10 ).

A t-test comparing the means returns a p-value of 0.167 (no significant difference) while a 2 sample KS-test returns a highly significant (p-value <10 −10 ) difference between the two distributions.

For genes from each cluster, he used a tool to run enrichment analysis and visually examined groupings of annotations that were highly significant (e.g. p ≤ 10 -10 ).

The difference between the fraction of paused and non-paused genes containing GrIn1 elements was highly significant (χ 2 = 82; P < 10 −10 ).

The first four inferred edges are highly significant (p<10 −10 for m = 1 to m = 4), the last one however to a much lesser extent (p = 0.009).

All quantiles yielded highly significant P -values ( P < 10 −10 ), confirming that the inclusion of the frame force significantly improves model performance.

This difference was statistically highly significant ( p < 10 −10 ).

Despite the small size of the validation set (412 d ( P , T ) and 694 d ( P , P ) interactions), representing only 1% of the possible secondary regulatory interactions, PhosTF predicted 40% of the known d ( P , T ) and 28% of known d ( P , P ) interactions, which was highly significant ( p < 10 −10 ) when compared to the rate of predictions overall (20% and 18% respectively).

We found 1060 upregulated genes in Wit49 and 396 in 17.94, with a highly significant overlap of 212 genes between the two cell-lines ( p < 10 −10 ) ( Figure 3 A).

The downregulated modules include 170 genes ( p < 1e-06), among them 13 highly significant genes ( p < 1e-10): COL10A1 , SAMD9 , PLPP4 , COMP , POSTN , IGHV4–31 , THBS2 , MMP9 , FNDC1 , HOPX , TMEM200A , INHBA , and SULF1 .

In an ANOVA with gain treated as a continuous regressor, the group effect for channels was highly significant (middle, p < 10 −10 ); lines connect channels that are not significantly different in post-hoc tests at level α =.05.

Of the 4694 SNPs, 389 MTAs were significant at P < 10 −8 , including 88 highly significant MTAs at P < 0.0000000001 (10 −10 ) ( Supplementary Data Table S3 ).

Figure 1 C shows across 9,320 gene promoters, RNA Pol II pauses at very similar locations among the five individuals; pairwise correlations ( Figure 1 D) are highly significant (p < 10 −10 ).

Hypergeometric enrichment analyses showed that these overlaps were highly significant ( p < 1e−10), supporting a non-random and biologically meaningful association among these factors (Fig. 3 C).

In this regard, the change in CD66b expression by bound cells was highly significant, p < 10 –10 and P < 10 –5 compared to BSL and CIRC respectively (Fig. 3 c).

These overlaps are highly significant ( P <10 −10 , hypergeometric test).