Excerpts

In this optimized model adjusted for baseline clinical characteristics, inadequate lymph node dissection remained a highly significant independent predictor of poorer survival outcomes (HR: 2.419, 95% CI: 1.447–4.047, p = 0.001).

We observed a highly significant positive correlation of recombination rates between the populations at the scale of 500-kb windows (Spearman’s rank correlation; rho = 0.931, P < 0.001; fig. 2 ; supplementary fig. 4 , Supplementary Material online).

Our results showed a highly significant (p < 0.001) association and a positive genetic correlation between resilience traits derived from body weight deviations (lnvar weight , lnvar standardized and lnMSE weight ) and tail biting wounds, lameness and mortality, although standard errors of genetic correlations were high.

The SNP at the FABP3 gene was recognized as a robust candidate marker for Jersey milk production, demonstrating highly significant associations in the assessment of TDMY ( p < 0.001), 305-DMY ( p < 0.001), and 305-DFY ( p < 0.001).

Basal and post-DEX DHEA-S levels (μg/dl) were 128.0 (95.5–171.5) and 92.0 (66.5–117.0), respectively; their correlation was highly significant (rho = 0.94, p < 0.001).

14 , 15 DM, by contrast, was characterized by near-universal skin involvement (100%) with Gottron papules in 83.3% and heliotrope rash in 41.7% — findings highly significant across subtypes (p < 0.001) and clinically valuable for early subtype identification at bedside.

The interaction between sugar and time was now highly significant (F 1,76 = 10.914, P = 0.001), with no significant effect of time (F 1,76 = 0.906, P > 0.05) ( Fig. 1E,F ).

Furthermore, the ANOVA analyses revealed highly significant ( p < 0.001) events by gender interaction effects, both for performance improvements in the years 2021 and 2022 compared to the respective reference values (Fig. 4 ).

As the number of electrodes increases, the classification accuracy using the graph theory features for the MI-BCI tasks demonstrates an increasing trend [confirmed by a one-way ANOVA under Alpha for ND feature, F (4, 250) = 2.95, p < 0.001].

CC literacy and FP literacy had a moderately significant correlation ( r = 0.35, p < 0.001).

The statistical model for the dependent variables (IB, MOR, MOE, TS, WA and SW) was highly significant ( p < 0.001) for all variables and the explanatory power that measures the strength of the relationship between the dependent and independent variables was high, as shown by η 2 values higher than 0.75 for all investigated panel properties.

One-way analysis of variance (ANOVA) revealed a highly significant difference in FBG levels among experimental groups at week 6 (F = 131.08, p < 0.001).

The results showed a strong and highly significant negative correlation between rMCC ReHo values and SSD severity ( r = − 0.843, P < 0.001), indicating that lower ReHo values in the rMCC are associated with more severe SSD symptoms.

The Q-test remains highly significant in all scenarios ( p < 0.001), confirming that heterogeneity is not driven by any single study but is instead intrinsic to the dataset, as shown in Table 5 .

The chi‐square test results further substantiate these findings, showing a highly significant difference across bed sizes ( χ 2 = 108.678, p < 0.001).

The analysis revealed highly significant linear, F (1, 48) = 37.250, p < .001, η 2 = .437, and quadratic trends, F (1, 48) = 15.065, p < .001, η 2 = .239, indicative of learning across trials.

The overall model was highly significant (Wald χ 2 = 18.6, p < 0.001), confirming that metabolic endotype contributes independently to the prediction of dialysis initiation beyond conventional risk factors. 3.9 Sensitivity Analysis for Albuminuria Exclusion.

Statistical significance levels P > 0.05 (ns) for not significant, P < 0.05 (*) for significant, P < 0.01 (**) for highly significant, and P < 0.001 (***) for very highly significant.

In the G groups, a clear trend was observed where median speed followed the order Trt − < Trt + < Ctrl (Tobs = 2197, permutation p = 0.001, Holm-adjusted p = 0.004).

ACE The most striking 2–2.5-year post-blast finding was the pronounced role of childhood adversities, a highly significant predictor across all PTSD outcomes (full: OR = 3.56, p < 0.001; 5 symptoms: OR = 3.21, p < 0.001; definition 1: OR = 2.71, p < 0.001; 2 cluster: OR = 2.32, p = 0.004; majority: OR = 2.40, p = 0.001; 6 symptoms: OR = 2.04, p = 0.008), in contrast to its non-significance at 6–7 months post-blast. 5.

control PDLs, where both TGFBR2 and TIEG showed highly significant correlation with TIMPs-1–3 and MMP-2 (correlation coefficients over 0.66, p < 10 − 3 , Supplementary Document 2 ).

Particularly, footprint length (F6), footprint width (F7), and heel-to-toe distances (F1–F5) exhibited highly significant sex-based differences ( p < 0.001).

Elevated levels of CRP was seen more in psoriatic patients with the metabolic syndrome when compared with patients without the metabolic syndrome and the difference was statistically highly significant ( P value = 0.001) [Figures 1 – 3 ].

Cumulative and daily transpiration Highly significant ( p < 0.001) differences can be observed for daily transpiration within treatment levels as well as across treatment levels.

Specifically, Gclc showed a significant difference ( p < 0.01), while the other nine FRDEGs displayed highly significant differences ( p < 0.001).