Excerpts

When age was added as a covariate, the associations remained highly significant ( P < 0.001).

Simple slopes analysis revealed theoretically illuminating patterns: peer influence effects were minimal among students with low social media usage (-1 SD: β = 1.23, SE = 0.89, t = 1.38, p = 0.168, d = 0.29) but substantial and highly significant among students with high social media usage (+ 1 SD: β = 5.67, SE = 1.34, t = 4.23, p < 0.001, d = 1.02).

Males who reported more than one sexual dysfunction as opposed to none were more likely to report an unintended pregnancy (19% versus 7% p = 0.01); this association was highly significant when considering sexual dysfunction hindering sexuality (37% versus 7%, p <0.001).

A meta-analysis revealed substantial heterogeneity in the maximum temperature-HSAD associations across prefectures, with an I 2 of 82.2% and a highly significant Cochran's Q test ( p -value < 0.001).

resulted in a highly significant neuroprotective effect (742.3 ± 25.8 RGCs/mm 2 ; p < 0.001; table 1 , Fig. 2B, C ).

A highly significant logarithmic trend for the train length effect was revealed for each condition [exact: F (1, 18) = 22.52, p < 0.001, η 2 = 0.56; wn: F (1, 18) = 228.30, p < 0.001, η 2 = 0.93; wp: F (1, 18) = 35.10, p < 0.001, η 2 = 0.66].

The linear predicted value (_hat) was highly significant ( p < 0.001), confirming that the selected covariates are independently associated of HBsAg serostatus.

However, for international collaborations outside South America, there was an increasing trend over the years (p < 0.001).

This was evidenced by their Childhood Autism Rating Scale (CARS), Social Responsiveness Scale (SRS), and Short Sensory Profile (SSP) scores (27.47 ± 7.95, 71.59 ± 11.55, and 156.47 ± 20.17, respectively), with a highly significant reduction in sensory hypersensitivity ( p = 0.001) compared to the WLT group, which presented more severe scores on CARS (35.89 ± 8.96), SRS (81.72 ± 7.68), and SSP (133.67 ± 11.65).

All comparisons between tadalafil (5 mg or 10 mg) and placebo were highly significant (p < 0.001).

Among survivors aged 60 years or older, survival declined stepwise from robust to pre-frail to frail, with highly significant between-group differences (log-rank P < .001; Fig. 3 B).

The results showed an extremely significant positive correlation between SAR and AbunR (Fig. 3a ; R 2 = 0.833, P < 0.001), suggesting that the population with higher ‘Space Accessibility’ would occupy more space at t 2 .

The vascularized area in the CAMs treated with bFGF was about 35% higher than in those treated with PBS, the difference being highly significant ( P < 0.001; t -test, double-sided; Figure 4A and 4D ).

Ordinal regression confirmed a significant trend toward worsening outcomes with higher Christie scores (β = 2.61 ± 0.69, p < 0.001; OR = 13.7 per step increase).

Pairwise comparisons of symptom change between timepoints Both depressive (HDRS) and anxiety (HAM-A) symptoms showed highly significant reductions from T1 to T2 ( p < 0.001) and continued to decrease significantly from T2 to T3 ( p < 0.001).

For patients who developed cardiotoxicity, the fall in left ventricular ejection fraction after a cumulative doxorubicin dose of only 200 mg m −2 was highly significant (left ventricular ejection fraction 49.7±1.8%, P =0.001 vs baseline).

Moreover, GC1 demonstrated a highly significant positive correlation with GCall (P < 0.001).

For both groups, there was a significant difference between the apical third and the other two-thirds, however, the difference between coronal and middle thirds was not statistically highly significant ( P < 0.001).

We also found a highly significant effect of stimulus type on mean accuracy by comparing the reduced model with a random-intercept only model (χ 2 (1) = 23.34, P < 0.001; ΔAIC = 21.34), with shape stimuli decreasing accuracy by 0.146 ± 0.025 (standard error) compared to color stimuli.

Results The results showed that hyperthyroid patients exhibited highly significant increases in the concentrations of fasting glucose and insulin ( P < 0.001) and significant increases in HOMA-IR level ( P < 0.05), compared to the control group [ Figure 1 ].

The results of the univariate linear regression analysis indicated a highly significant negative correlation between the sqrt of MMA and cognitive score ( B = −0.47, p < 0.001).

The heat shock temperature was found to have a highly significant effect on activating ascospore germination (two-way nonparametric ANOVA; H = 43.20, df = 3, p < 0.001) ( Supplemental Figure S2 ).

Physicians' attitudes about depression Highly significant differences (p ≤ 0.001) were found between the attitudes of GPs and psychiatrists for 10 of the 20 statements on the DAS (Table 5 ).

Indeed, when stratifying the patients according to this dichotomous cut-off, the difference was highly significant, p < 0.001 ( Figure 2 D); the median OS for the fit patients (4/16 died, 25%) was not reached, while the median OS for the unfit patients (82/104 died, 78.8%) was 12.1 months (IQR: 6.1–29.0).

The analysis revealed a highly significant interaction (Y × S, p < 0.001) for these key compounds, particularly for ethyl acetate and isoamyl acetate.