Barely Significant

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highly significantp = 0.0010.0× alphaqualifiedgold
The PERMANOVA (with 999 permutations) revealed highly significant differences in microbial community composition across all groups ( p = 0.001), indicating that the experimental interventions collectively exerted a substantial impact on the gut microbiota architecture.
highly significantP < 0.0010.0× alphaqualifiedgold
However, for head position, although there was also no main effect, there was a highly significant interaction between head position and wave [F (2, 18) = 13.0, P < 0.001], such that the second wave had a highest response in head-down position, in contrast to the first wave that was maximal in the neutral position ( Fig. 5 B ).
highly significantp < 0.0010.0× alphaqualifiedgold
As the correlation between pull-out force and pull-out force per area was found to be highly significant and very strong (Pearson’s correlation coefficient R = 0.970, p < 0.001), pull-out force was used as the only biomechanical parameter for the remaining animals. 2.6.
highly significantp < 0.0010.0× alphaqualifiedgold
The time of measurement and the treatment × time interaction were highly significant (monthly measurement: F 16,160 = 6.78, p < 0.001, treatment × time: F 16,160 = 3.36, p < 0.001), indicating that all populations were growing, and that there were time-dependent differences in growth rates in the inbred and outbred founded populations (see Figure 3 ).
highly significantp < 0.0010.0× alphaqualifiedgold
The correlation between the early BMD values and the 24-28 month post delivery values were highly significant and reliable (Pearson correlation coefficient 0.95, p < 0.001 with 2-tailed analysis), as was the correlation between the late pregnancy BMD values and the 24-28 month post delivery value (Pearson correlation coefficient 0.97, p < 0.001 with 2 -tailed analysis).