Barely Significant

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highly significantp < 0.0010.0× alphaqualifiedgold
To further solidify the molecular signatures of the subgroups 1–4, we performed RNA-based single-sample GSEA, which demonstrated robust and highly significant enrichment of the gene sets “stemness”, “synapse assembly”, “gonadotrophs” and “secretory vesicle”, respectively ( p < 0.001; Fig. 2d and Supplementary Data 5a–d ).
highly significantp < 0.0010.0× alphaqualifiedgold
Statistical significance of shape variation The pairwise Mahalanobis distances based on shape, for both landmark- and outline-based shapes, were highly significant ( p < 0.001) between Fasciola intermediate forms and F . gigantica or F . hepatica .