Barely Significant

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highly significantp = 0.0050.1× alphaqualifiedgold
Among the 32 subjects in the bryostatin treatment group in the Moderate Stratum Cohort in the #203 study, we found a difference = 4.1 points (with imputed data) in the mean SIB at week 13 from baseline (See Table 5 below), a result that is highly significant ( p = 0.005).
a clear trendp = 0.0050.1× alphagold
Self-perceived oral health status showed a clear trend: participants who rated their oral health as “Good” (Estimate: −5.28, p = 0.005) or “Very good” (Estimate: −6.12, p = 0.003) had significantly lower dental erosion scores compared to those with poorer self-perception, with “Satisfactory” ratings approaching significance (Estimate: −3.85, p = 0.052).
an increasing trendp < 0.0050.1× alphagold
Additionally, when analyzing each of the temperature indicators and the sum of precipitation for the first 12 days of the pied flycatcher nestling life, we found a statistically significant increase (an increasing trend) for each temperature (year × T mean_12 r = 0.57, p < 0.005; year × T max_12 r = 0.38, p = 0.002; year × T min_12 r = 0.45, p < 0.005), while the decrease for the sum of precipitation showed a decrease in 2015–2019 (year × P 12 r = − 0.44, p < 0.005) (Fig. 3 ).
highly significantp = 0.0050.1× alphaqualifiedgold
A categorization by surgical resection of liver metastases demonstrated a highly significant difference ( p = 0.005) in OS between those patients who underwent surgical resection (median OS 32.8 months; 95% CI, 21.42–44.18; n = 11) and those who did not (median OS 12.20 months; 95% CI; 5.58–18.82, n = 31) ( Figure 3 A).
highly significantP = 0.0050.1× alphaqualifiedgold
Immunostaining of perforin and granzyme B, both cytotoxic effectors, showed only few positive cells without differences between BD and PsA (Table 1 ), but the SF levels of perforin showed a highly significant four- to fivefold increase in BD (1,168 pg/mL, range 428 to 2,010 pg/mL) versus PsA (278 pg/mL, range 132 to 642 pg/mL) ( P = 0.005) (Table 2 ).