The inhibition of each infection by heparin was highly significant ( P < 10 −6 by χ 2 test, comparing infected and uninfected populations).
Excerpts
Figure 2A shows a linear increase in the execution times of both software with the number of SNPs and the correlation is highly significant for both comparisons ( r = 0.98 and 0.99 respectively, P < 10 −6 ).
The RR ratio was 0.29 (95% CI 0.18 to 0.48) and was highly significant ( P < .000001).
The log10-transformed engorged larval weight was a highly significant predictor of the log10-transformed unfed nymphal weight, and the former explained 72.7% of the variation in the latter (Fig. 4 ; regression: F 1, 651 = 1738, p < 0.000001; correlation: r = 0.854, t = 41.859, df = 652, p < 0.000001).
Planned comparisons revealed a similar Laterality effect in French and Spanish [ F (1, 120) = 1.78, MSE = 32.31, p = 0.19, η 2 = 0.005] but a highly significant difference between these two groups and the Arabic group [ F (1, 120) = 223.12, MSE = 32.31, p < 0.000001, η 2 = 0.65].
The association between Harvard step test and overweight was statistically highly significant (p=0.000001) with odds ratio of 24.65 (C.I. = 9.97; 68.68). 4.
This reduction was highly significant according to both the paired t -test (t = 10.43, p < 0.000001) and the Wilcoxon test (Z ≈ −3.06, p = 0.00024).
SNP with call rates < 0.98, minor allele frequencies (MAF) < 0.03 and highly significant deviations ( P < 10 -6 ) from Hardy-Weinberg Equilibrium (HWE) were also excluded.
However, this may be due to a difference in the linkage phase between the imputed alleles and causal mutations in each of the breeds, as the marginal significance of SNP ( P > 1 × 10 −6 ) just upstream of this QTL in the CH and LM populations does suggest that a QTL extending from the 57.9 to 58.2 Mb on BTA18 influences DCD in multiple breeds, albeit to a different extent.
Prior to statistical analysis, SNP data were filtered, using the BITE package 61 in R v4.0.5, according to the following criteria: (i) SNPs with call rates less than 95%, (ii) minor allele frequencies less than 5%, (iii) missing genotypes more than 5%, and iv) SNPs with highly significant deviation from the Hardy–Weinberg equilibrium ( P -value < 10 −6 ) 62 were eliminated.
This interpretation is further supported by the Pairwise Homoplasy Index (PHI) test implemented in SplitsTree, which returned a highly significant result ( P < 1e-6), suggesting that the observed pattern of site incompatibilities is unlikely to arise under a strictly clonal (non-recombining) model.
The difference between the sharpness indices of the native 2D images and the super-resolved images (both regularizers) was highly significant ( p << 10 −6 ) for both subjects, with the super-resolved images being less sharp.
This effect is small; on average people get about 6% faster and spend about 1% less time buzzing, but highly significant ( p <10 −6 for both metrics, t -test).
Combining two trial populations, ASA, promptly started in the acute setting, showed a highly significant reduction in recurrent IS (1.6% vs. 2.3%; p < 0.000001).
3 Results 3.1 Nutrient main effects The overall mean effect of P was found to be highly significant (p < 1e −6 ) with an average yield gain of 251 kg ha −1 at an average rate of 15 kg P ha −1 .
[ 7 the correlation between nodularity and infection is highly significant (p<0.000001).
Specifically, the evidence grading criteria were as follows: If the association was supported by a highly significant random-effects ( P < 10−6, a threshold considered to substantially reduce false positive findings) 10 – 13 , a sample size of more than 1000 cases, P < 0.05 in the largest study, I2 < 50%, absence of small study effects, a PI excluding the null, no evidence of excess significance bias, and P < 0.05
Results The statistical analysis of the Dice coefficients and the BLD values resulted in highly significant differences (p<10 −6 ) for the 5-mm and 8-mm local RRs vs the global, bony and 1-mm local RRs.
The difference between CD24+/CD44- and CD24-/CD44+ cells with respect to their position in the E-M state space was highly significant (p<10 –6 ).
This 47% reduction in the value of GEZI in T2D subjects relative to ND subjects was found to be highly significant ( p <10 –6 ) via a likelihood ratio test.
Briefly, meta-analyses were considered to be supported by robust evidence if the association was supported by more than 1000 cases, a highly significant association (the random effects model had a P -value ≤ 10 −6 , a threshold that is considered to substantially reduce false positive findings) [ 31 – 33 ], there was absence of high heterogeneity based on I 2 < 50%, the 95% PI excluded the null value, and there was no evidence of small-study effects or excess statistical significance.
Only the model with KPR yielded a satisfactory fit, and a likelihood ratio test, with the absence of KPR being the null hypothesis and the presence of KPR being the alternative hypothesis, showed highly significant support for the KPR model (p<10 −6 , Figure 7D,E,F and Figure 7—figure supplement 5 ).
Above 75, an increasing trend was observed with 85+ years showing AAPC of 1.38 (95%CI, 1.07 to 1.69, p<0.000001).
As expected, we observed a highly significant, positive relationship between metabolic rate and body mass ( R 2 = 0.53, F 1,175 = 193.65, P < 0.000001; log-transformed data).
For BRCA2 both ER and grade were highly significant predictors of mutation status, and the interaction of ER and grade was also quite significant (χ 2 = 28.3, 2 df , P <10 -6 ).