Excerpts

The observed signal for G is statistically highly significant as evidenced by randomization calculations ( P -value < 10 − 6 , Figure 2 B).

The intra-correlations of IgE levels among newborn, 1.5, 3 and 6 years were highly significant correlated one another ( P <10 −6 ; Table 2 ).

This is a highly significant (P << 10 -6 ) and remarkable overlap considering that i) the number of breeds was doubled here in relation to [ 3 ], ii) the number of tissues was quite different between both studies, 16 in [ 3 ], five here; gonads, the most variable tissue, was not studied in [ 3 ], and iii) the statistical inference method was different.

A strong, highly significant correlation between the frequency of tracking interruptions with the right and left hand was found (Pearson correlation, r = 0.834, p<10 −6 ).

Regardless of the bootstrapping approach, while there is overlap in distributions of bootstrapped estimates of t for LR and HR loci for both species pairs, the distributions are clearly significantly different (Mann-Whitney U test, p <10 −6 ).

the nascent bond show that all of these active site dynamics are highly significant with p < 10 −6 ( Fig.

In confirmation of our hypothesis, there was a highly significant, 9.4-fold, increase in the maximal tetanic force (7.5±0.94 g versus 0.8±0.2 g; p=≤0.000001) elicited by ONS in the engrafted OST group of SOD1 G93A mice at late-stage disease, compared to age-matched untrained SOD1 G93A mice (132.4±6.8 days versus 133±6.9 days; n=7 and 11, respectively; Figure 5C–G and Appendix 1—table 3 ), although OST did not alter contractile rate characteristics ( Figure 5—figure supplement 5A–C ).

However, for intergroup comparison, the difference between the two modes was found to be highly significant in both sedated and awake states if we considered inspiratory hold in PAV+ as PMI ( P = 0.000001 for both states).

Mean annual precipitation shows a very weakly significant primary linear correlation with erosion rate (R 2 = 0.017 and p-value = 0.000001; Fig 3 ).

All 157 SNPs with highly significant associations ( P <1 × 10 −6 ) in this region, were in high linkage disequilibrium with rs188686860 and rs115635831 ( r 2 >0.90), and were located proximal (Hg19: 201,717,014-201,995,860) to the CASP8 gene ( Supplementary Table 15 ).

6, the text now reading “Numbers of SNPs that were nominally significant ( P < 1 × 10 −6 ) in the IPF GWAS meta-analysis and also eQTL” originally read “Heatmaps presenting the numbers of eQTLs that were nominally significant ( P < 1 × 10 −6 ) in the IPF GWAS meta-analysis” and has now been corrected in the HTML and PDF versions of the article.

Briefly, meta-analyses were considered to be supported by robust evidence if the association was supported by more than 1000 cases, a highly significant association (the random effects model had a P -value ≤ 10 −6 , a threshold that is considered to substantially reduce false positive findings) [ 31 – 33 ], there was absence of high heterogeneity based on I 2 < 50%, the 95% PI excluded the null value, and there was no evidence of small-study effects or excess statistical significance.

The mortality rate for NH white group also demonstrated an increasing trend from 0.132 to 0.196 from 1999 to 2001 (APC: 22.3406; 95% CI, 4.4622 to 39.741; p < 0.000001), with a rise to 0.286 in the mortality rate from 2001 to 2018 (APC: 2.8652; 95% CI, −3.0608 to 3.5123; p = 0.119176), followed by an increase to 0.414 from 2018 till 2022 (APC: 10.7260; 95% CI, 5.725 to 20.0315; p < 0.000001).

SNP with call rates < 0.98, minor allele frequencies (MAF) < 0.03 and highly significant deviations ( P < 10 -6 ) from Hardy-Weinberg Equilibrium (HWE) were also excluded.

Note that the difference in PS rates is highly significant ( P < 10 −6 ). 10 μg of protein isolated at 1 h was processed by 8%PAGE/SDS for fluorographic auradiography with PPO.

Planned comparisons revealed a similar Laterality effect in French and Spanish [ F (1, 120) = 1.78, MSE = 32.31, p = 0.19, η 2 = 0.005] but a highly significant difference between these two groups and the Arabic group [ F (1, 120) = 223.12, MSE = 32.31, p < 0.000001, η 2 = 0.65].

The multiple sclerosis patients showed a highly significant negative ΔWMV compared with the control subjects (mean multiple sclerosis ΔWMV = − 56,417 mm 3 , SD = 43,267 mm 3 , t = − 5.68; P < 0.000001).

The inhibition of each infection by heparin was highly significant ( P < 10 −6 by χ 2 test, comparing infected and uninfected populations).

This interpretation is further supported by the Pairwise Homoplasy Index (PHI) test implemented in SplitsTree, which returned a highly significant result ( P < 1e-6), suggesting that the observed pattern of site incompatibilities is unlikely to arise under a strictly clonal (non-recombining) model.

A Chi-square test showed these differences to be highly significant (χ 2 = 236.6; df = 17; p < 0.000001), confirming that germinated seeds are much more likely to occur on the side to which the ants do not have access.

ANOVA with the main factor Age-Group (adults, children) and repeated measures factor Velocity (3 conditions) revealed a highly significant effect of Velocity on gamma power (F (2,122) = 172.8, ε = 0.87, p < 1e −6 ; η 2 = 0.74), but no effect for the Age-Group or the Age-Group*Velocity interaction (p’s > 0.6).

To individually test candidate SNP pairs for interaction, we tested the nominally significant interaction results ( P < 1.0x10 -6 ) from the PLINK[ 63 , 64 ] epistasis test.

In contrast, highly significant differences were observed among the crop species (F 2,18 = 615.70, p < 0.000001; Table 1 ).

These clusters are robust to changes in network parameters and are highly significant (p-value < 1 x 10 -6 , permutation tests).

There was a highly significant time effect, group effect and interaction between time and group ( p < 10 –6 ).