Excerpts

There was a strong positive correlation between DAO and histamine levels in all the groups that was statistically highly significant ( p = 0.00001) (Table 6 ).

A correlation matrix was calculated for these genes, using Pearson Product-Moment Coefficient, defined as r x , y = ∑ i = 1 n ( x i − x ̄ ) ( y i − y ̄ ) ( n − 1 ) δ x δ y The values of Pearson correlations above 0.3 are statistically highly significant (p-value < 0.00001 after Bonferroni correction for multiple testing [ 85 ]).

The difference between the MS and the control group regarding the frequency of a positive MRZ, MRZB or MRZBU reaction, as defined by a bi- or trispecific response, was highly significant ( p < 0.00001, Mann–Whitney U test, irrespective of whether the single steroid-treated control patient was included or not).

Logistic regression testing the effect of sequence length on whether or not the query sequence have at least one BlastX hit ( E value 10 -5 ) was highly significant (p-value < 0.00001).

While the difference in colony size ratio between 0 and 125 μM EDTA for PY79 is significant by a two-tail t -test ( p < 0.02), the difference between these concentrations for σD ::tet is highly significant ( p < 0.00001).

But the actual percentage of double-positive bipartite synapses was much lower, only 4.8 ± 1.8%, and the difference was highly significant (p < 10 -5 , two-tailed t -test).

The patient is assigned the high or low risk of relapse category if the score is ⩾2.41 or <2.41, respectively, with highly significant differences in RFS ( P <10 −5 ) and OS ( P <10 −5 ) between both groups.

The FLA demonstrated the shortest mean duration (10.88 ± 1.2 min), with a highly significant difference (analysis of variance F-test, P < 0.00001) compared to the eyebrow, bifrontal trans-basal, and pterional approaches.

Although, individually, 5 studies data did not reach statistical significance [ 63 , 80 , 87 , 88 , 99 ], the overall effect showed the reduction of CRP levels after supplementation (MD: −1.10, 95% CI: −1.26, −0.93, p < 0.00001, Figure 13 ).

In both residue-level and protein-level assessments the improvement in performance of aaRNA over the alternative methods was highly significant ( P -values <10 −5 and <10 −10 , respectively).

The absence of effect in the non‐treatment groups suggests that there may be a true treatment effect from most exercise regimes. Vergence facility (VF) There was a highly significant change in responses (main effect F 1,145 = 73.8, p < 0.00001) and marginal group/change interaction (F 7,145 = 1.93, p = 0.07).

In the SA27063 × A17 F 2 population a highly significant quantitative trait locus (QTL, LOD = 7.37; P < 0.00001) named r esistance to the n ecrotroph P homa m edicaginis one ( rnpm1 ) genetically mapped to the top arm of linkage group 4 (LG4). rnpm1 explained 33.6% of the phenotypic variance in the population's response to infection depicted on a 1–5 scale and was tightly linked to marker AW256637 .

We observed a strong and highly significant overlap of 516 genes (Monte-Carlo empirical P < 10 −5 , normal approximation P < 10 −300 , Additional file 1 : SI Fig.

The regression through the origin of PIC %mC on PIC logCvalue was highly significant (adjusted R 2 = 0.376, F 1, 40 = 25.66, p = 0.00001).

The overlap between the differentially expressed genes was statistically highly significant ( P < 10 −5 ), pointing to a biological relationship.

Only electrodes with a highly significant correlation relative to the null were retained ( P < 10 −5 ).

There was a strong relationship with sleep disturbance as indicated by highly significant correlations with all four SQS subscales (all p < 0.00001) but not with hours of sleep.

the time from diagnosis (in radically treated patients) until the first appearance of regional recurrences or distant spread, and overall patient survival (survival time until death from thyroid cancer) were compared across seasons. RESULTS Registry cases The 2627 thyroid cancer cases diagnosed in Norway during 1970-85 showed a highly significant time-effect when incidence was compared across 12 months (X2 = 119.3, P<0.00001) or four seasons (x2 = 35.6, P<0.00001), being highest during the last 3- month period October-December (Figure IA).

There was a highly significant pre/post decrease in the in the emotional exhaustion (p < 0.00001) and depersonalization scores (p < 0.001), with highly significant increase in the personal accomplishment (p < 0.00001) scores.

All primary outcomes showed significant improvement post treatment at BF-corrected alpha of p < .0028: There was a highly significant post-treatment drop of general psychiatric symptoms (SA-45 global severity index; p < .00001, d = 1.08).

Although separation of the samples from the neighboring countries of Brazil and French Guiana was not visually resolved by the first two principal components in PCA (POV = 21), the F ST value was still highly significant (F ST = 0.10, p < 10 -5 ) ( Fig. 5B ).

Pairwise F ST values with outlier SNPs were all highly significant ( p < 0.00001) and were highest for comparisons involving the conventional plot ( F ST = 0.071 for conventional versus semi-conventional; F ST = 0.070 for conventional versus semi-organic; F ST = 0.049 for semi-conventional versus semi-organic).

The chi-squared test yielded a value of 323.71 with four df, which indicated highly significant heterogeneity ( P < 0.00001), as demonstrated in the forest plot depicted in Figure 3 .

Furthermore, a robust association between observed and predicted responses for TC degradation was evident from the highly significant regression model (p-value < 0.00001), high coefficient of determination (R2 = 0.9886), and well-adjusted R2 value (0.9780) 18 , 59 .

The overall Repeated Measures ANOVA applied to compare the values of n i obtained for all three ant groups revealed a highly significant effect of the between-subject effect „group” ( F 2,117 = 27,297, P < 0.00001), a highly significant effect of the within-subject effect „time” ( F 9,1053 = 31.303, P < 0.00001), and a significant interaction „group” x „time” ( F 18,1053 = 1.721, P = 0.031).