Excerpts

MSC-induced enhancement of AML cell proliferation in transwell cocultures was highly significant also when analyzing the overall results for this larger group of patients (Figure 2 A; p < 0.00001, Wilcoxon’s signed-rank test).

As can be clearly seen, there was a highly significant reduction in paw withdrawal latency after the CCI ( P < 10 −5 ; ANOVA).

Gender exhibited a highly significant association (X2 = 45.9, p < 0.00001), highlighting differences in awareness levels between males and females; women are more knowledgeable than men.

On these grand-averaged data, a Z-Score computed as the difference between amplitude at the frequency of interest and the mean amplitude of 20 surrounding bins divided by the standard deviation of the 20 surrounding bins (e.g., Rossion et al., 2012 ; Liu-Shuang et al., 2014 ; see also ‘Materials and methods’) was highly significant at electrode Oz (Z = 52.9, p < 0.00001).

Seventy markers were excluded from the following analysis, as they showed highly significant departure from Hardy Weinberg equilibrium (P<10 −5 ), obtaining 5,192 markers for the following analysis.

This difference in means is highly significant ( P <0.00001).

Nevertheless, a highly significant correlation (Pearson’s correlation coefficient R = 0.968; p < 0.00001) is observed between the frequency of usage of an ataxin-3 amino acid site as a binding site in the two datasets.

There was a positive and highly significant correlation between the numbers of teeth on oral versus pharyngeal jaws ( r = 0.53 without P. nigra and r = 0.66 including P. nigra ; p < 0.00001; Figure 2 J).

All three two-way interactions between the main effects were found to be highly significant (p<0.00001), thus estimates and corresponding significance levels are not given for the main effects.

This search recovered the GCS2 HMM (based on PDB: 1r8g) as the highly significant best hit (p-value= 10 -5 ), with an alignment spanning the entire length of the GCS2 catalytic domain and matching all key conserved motifs (Fig. 2 ; see below).

A genome-wide association study (GWAS) screened 297,876 SNPs and identified highly significant associations ( p < 1 × 10 −5 ) with head smut resistance in sorghum.

The combined group demonstrated a substantially larger and highly significant positive effect (SMD = 2.02, 95% CI: 1.83 to 2.21; P < 0.00001).

The reduction in ulcer size from baseline to day 35 was statistically highly significant ( p < 0.00001).

2011 ), which is highly significant (permutation P < 1 × 10 −5 ) ( Fig. 3 B).

Using our phytohormone gene list, we identified a highly significant overrepresentation ( p < 0.00001) of phytohormone genes 1 h before (zeitgeber time 23; ZT23) and 1 h after dawn (ZT0) under short-day photocycles.

Highly significant (P < 0.00001) pairwise correlations were observed for 431 out of the 703 possible pairs for the 38 probesets examined in this study.

There is a highly significant correlation of the expression levels of individual ta-TRIM s as determined from EST and from RNA-Seq data (Pearson correlation test, P < 0.00001), confirming that the variation observed among ta-TRIM s is not an artifact of the mapping algorithm or the selected parameters.

Three homogenous studies reporting procalcitonin documented a highly significant value ( p < 0.00001) with a I 2 value of 57% and odd ratio of 5.77 (95%CI: 3.35, 9.95) beyond the cut off value of 0.1 ng/mL [ Figure 6b ].[ 14 , 15 , 20 ] Investigation of heterogeneity Heterogeneity was found in all the comparisons with I 2 value ranging from 56% to 99% [ Table 3 ].

The increase in PNN density (normalised to the cross-sectional area of the neostriatum) between P10 and P14 was highly significant (one-way ANOVA, Tukey-Kramer test; F(5, 48) = 142.14, P<<0.00001; Fig 7A ).

The tests are all highly significant, with p < 0.00001.

ESM-1b t s + ECFP) is statistically highly significant (McNemar’s test: p < 10 −5 ).

Linkage disequilibrium and haplotype analysis The LD test revealed that LD was moderately significant between T182C and A3081T (|D'|=0.702, r 2 =0.275, p-value=<10 -5 ) but not between A3081T and G1287A or between T182C and G1287A ( Table 5 ).

This analysis revealed a single highly significant CCA mode that relates functional connectomes to subject measures (r=0.87, P<10 −5 corrected for multiple comparisons across all modes estimated).

There was no significant difference in MM96L when siNF1 was compared with miR-514a, whereas in MM253, particularly at higher drug dosage (10-100nM), the differences between siNF1 and miR-514a, were highly significant ( p < 0.00001) (Figure 5a ), indicating that the mode of BRAFi resistance was different, possibly due to other targeted genes of miR-514a.

The difference in classification performance between sexes was highly significant (Mann–Whitney U‐test, p < 0.00001, Figure 4A , effect size d = 0.8), showing a strong sex‐related bias in models trained without using ERP features.