Barely Significant

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highly significantp < 0.00010.0× alphaqualifiedgold
When the refined model was applied to the KRAS-WT CRC data, the resulting difference in PFS between the predicted-sensitive and predicted-resistant group was highly significant (median 147 days vs. 56.5 days in the predicted sensitive and resistant groups, respectively, p < 0.0001) (Figure 3B and 3C ).
highly significantP < 0.00010.0× alphaqualifiedgold
Statistical analyses Microsatellite diversity, Hardy-Weinberg and genotypic linkage equilibrium GenePop 3.4 [ 14 ] was initially employed to screen for deviations from Hardy-Weinberg (H-W) equilibrium and two loci (BFRO4 and ONE2) were excluded due to highly significant heterozygote deficiency (P < 0.0001) in several populations, likely indicating the presence of null alleles.
highly significantp -value < 0.00010.0× alphaqualifiedgold
Selection and Functional Role of VAMP5 as a Diagnostic Biomarker of TB We followed the criteria of showing a high correlation with other EV-related DEGs, highly significant expression with a p -value < 0.0001 in both validation sets, function in vesicle-mediated transport, and a high AUC to select the VAMP5 gene, which can be a potential diagnostic biomarker of TB.