The 6-OHDA lesioning ( n = 8) caused a near-complete and highly significant (96.8 ± 1.8%, Two-Sample t -test, p < 0.0001) abolishment of DAT at the level of the CPu ipsilateral to the lesion in experimental cohort 1.
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RNL lower than 0.650), compared to the controls (statistical differences highly significant, p < 0.0001 for Pt-3, Pt-5 and Pt-8 and p < 0.001 for Pt-4) ( Figure 6 ).
ANOSIM detected highly significant differences in meristic counts between intensive and organic lots (R = 0.04; p<0.0001).
There was an overall weak, albeit highly significant, correlation between the sCD26 concentration and the DPPIV activity ( r s = 0.35, P = 0.0001, n = 150).
The mean change from baseline was 0.97 ± 0.40 to 0.39 across all follow-ups with a highly significant P- value of < 0.0001, indicating a sustained and statistically significant enhancement in contrast sensitivity over the 12 months [ Fig. 2 ].
Time lag was highly significant ( P < 0.0001) in PE+IOL group, while it was significant in rest of the surgeries in learning phase only and it neither impacted the surgeons comfort, nor the surgical outcome.
Lipid Synthesis and Transcriptional Control ( Figure 9 b) For lipid metabolism-related transcription factors, Srebf1 showed a highly significant phase effect (F(1, 25) = 24.42, p < 0.0001, partial η 2 = 0.49, q = 0.0001), with higher expression at ZT3 than at ZT15, and a trend toward an exercise effect (F(1, 25) = 3.72, p = 0.0653, partial η 2 = 0.13) that was not confirmed after FDR adjustment.
Next, we analyzed the expression of cell cycle‐related protein after H 2 O 2 exposure and found an increasing trend of P21 protein expression level ( p < .0001; Figure 6d,e ).
We find a highly significant correlation between p53 protein synthesis in leukemic blast cells and the secondary plating efficiency of these cells (p = 0.0001).
Incubation with Wnt3a conditioned medium (CM) resulted in a small but statistically significant (p = 0.017) increase in Wnt pathway throughput, measured by luminescence following transient transfection of the Super Topflash reporter construct, in NCM460 cells and a robust and highly significant increase (p < 0.0001) in RKO cells (Figure 2A ).
3B1 and 3B2 indicated highly significant effects of gabazine ( p < 0.0001) and behavior ( p = 0.0002), and further indicated a significant interaction ( p = 0.0314).
Among them, phages PA-312, PA-575, and PA-711 showed the strongest activity, producing highly significant reductions in bacterial viability ( p < 0.0001).
Results: We found a highly significant reduction of circulating pDCs ( p < 0.0001) and in bone marrow ( p < 0.0001) of MM patients compared to HD.
As seen in Figure 3 A,B, there was a highly significant negative correlation (r = −0.304 and r = −0.335) ( p < 0.0001) between the serum VB 12 level and the serum MMA level ( Figure 3 A) or between the serum VB 12 level and the plasma tHCY level ( Figure 3 B) in a given patient, and the serum MMA level directly (r = 0.437) and significantly ( p < 0.0001) correlated with the plasma tHCY level in a given patient ( Figure 3 C). 2.3.
Importantly, a highly significant association was found between the G-allele and response to therapy in HCV genotype 1-infected patients (P<0.0001) but not in HCV genotype 3-infected patients.
The correlation between confidence in vaccine effectiveness and safety was moderate but highly significant (Spearman’s rho = 0.38, p < .0001).
In the anterior ALPS (aALPS), the bvFTD group showed significantly lower values compared to the NC group (bvFTD: 1.24 ± 0.14 vs NC: 1.54 ± 0.12, Cohen's d = −2.2568), with highly significant group differences in all models ( p < 0.0001).
The ANOVA results for the set (i) showed highly significant and statistically greater Ks in the set of 26 mitogenomes: Ks = 1.618 ± 0.019, Ka = 0.384 ± 0.019 ( n = 325), F = 1949.2, d.f. = 1; 648, p < 0.0001 (effective hypothesis decomposition).
The difference in the proportion of the number of citations relative to the number of published studies in the different areas was highly significant ( x 2 = 50.02, p < 0.0001).
We found a highly significant correlation between age and HNK-1 antigen expression (r = 0.78, P < 0.0001).
Results A highly significant association (p < 0.0001) was observed for joint space narrowing (JSN) as well as for osteophyte formation between the three groups.
Finally, as in our gene-expression data, we observed highly significant correlations between the intra-tumoral cell counts of the myeloid and main (T, B or NK cells) lymphoid subset ( Figure 3 j-o, p < .0001).
In order to evaluate the diagnostic value of BLSP in terms of tissue-specificity, we compared this integrated group to all UC cases and observed a highly significant ( p < 0.0001) difference for all CpGs ( Table S5 ).
There were highly significant differences in the number of OSCE stations and the number of MCQs set over the study period ( p < 0.0001).
Statistical analysis confirmed that the tumor growth inhibition by Mn-TK and Mn-BR was highly significant ( p < 0.0001), highlighting the efficacy of these treatments.