Area under the curve (AUC) of the HFA, TIMI RS and Goldman tools for the endpoint of MACE was 0.54, 0.71 and 0.67, respectively, with the difference between the tools in predictive ability for MACE being highly significant [chi 2 (3) = 67.21, N = 276, p < 0.0001].
Excerpts
Another t -test was conducted for the average PDI values between the 2 μm/30 nm compared to PEG, which showed an extremely significant value ( p ≤ 0.0001).
Two-way ANOVA of the normalized transcript counts acquired from microglia incubated for 24 h with vehicle ( n = 3), UNMOD myelin ( n = 3), or CIT myelin ( n = 3) revealed a highly significant difference between groups ( F (27,368, 82,110) = 1.775, P < 0.0001).
At this time point, the difference was still highly significant ( p < 0.0001).
The global effect of fixation was highly significant (likelihood‐ratio p<0.0001), underscoring fixation strategy as the principal determinant of postoperative FWB in this cohort.
In the middle quartiles ( Figure 4 D,E), donepezil-treated aged mice showed highly significant reductions in alveolar size compared to aged controls ( p < 0.0001).
The difference between the distribution center of the two subpopulations was highly significant [ F (6, 85) = 11.246, P < 0.0001].
Although a high percentage of irregular menstrual cycles was found in all groups, it was more frequent in the PA group than in the AA and EA groups (62%, 37.5%, and 31.2%, respectively), with a highly significant association (p=0.0001).
Differences among median results obtained at the three times of observation were all highly significant ( P < 0.0001; Figure 1 A).
In this study investigating affective disorder patients, there was also a highly significant positive correlation (τ = 0.15, p < 0.0001, n = 788) between the total Hamilton score and the total CTQ-score as we already reported previously [ 27 ].
Overall, patients with AD demonstrated highly significant correlations with BPF in all cognitive domains examined (Executive: β = 0.26, R 2 = 0.07, P <0.0001; Mental Processing Speed: β = −0.31, R 2 = 0.08, P <0.0001; Memory: β = 0.30, R 2 = 0.09, P <0.0001).
Linear regressions for percentage of puffy fruit on the markers solcap_snp_sl_33701, solcap_snp_sl_8669, solcap_snp_sl_100164, solcap_snp_sl_20440, solcap_snp_sl_18619, solcap_snp_sl_4963, and solcap_snp_sl_531 located within 1-LSI on Chr 1 ( Figure 2 ) were highly significant ( p < 0.0001) in the validation population.
A linear regression analysis also showed that there was an extremely significant correlation between miR-4728-3p and mir-4728 (R: 0.999, p < 0.0001) ( Figure 3C ).
There was a highly significant difference between the amplitudes of all participants with RGC pathology grouped together versus the participants with no evidence of RGC pathology ( p < 0.0001).
The results showed that, following correction, the pooled MD for DBP remained highly significant at −7.83 mmHg (95% CI: −9.88 to −5.79, p < 0.0001).
ANOVA indicated a highly significant ( p < 0.0001) difference in the average percentage of window filtered Sum Vector Magnitude among low-/high-acceleration ADLs and fall.
There was no significant difference between littermate controls and Jna/+ mutants when BrdU was injected at E12.5 (F[9,189] < 1; P > 0.05), however there was a highly significant difference when injected at E14.5 (F[9,198] = 4.75; P < 0.0001), and at E16.5 (F[9,270] = 13.3; P < 0.0001).
The comparison between PBS and US16 showed a highly significant difference ( P < 0.0001), as did the comparison between PBS and US16.1 ( P < 0.0001), indicating a marked difference in pixel intensity values between these groups.
After adjustment for selected covariates, there was an increasing trend in the adjusted PRs for cancers of all sites by duration of diagnosed diabetes among men ( P < 0.0001 for linear trend) ( Fig. 1 A ) and women ( P < 0.0001 for linear trend) ( Fig. 1 B ).
Compared to the manual approach of biometric data export and intraocular lens calculation (76.7 ± 12.3 s) as well as the manual export of the reference image to a portable external storage device (26.8 ± 5.5 s), a highly significant saving of time was achieved ( p < 0.0001).
The univariate analysis of factors associated with SFV infection showed a highly significant association with male sex (p<10 −4 , χ 2 = 24.6), with the Pygmies (p<10 −4 , χ 2 = 20.85), hunting (p<10 −4 , χ 2 = 233.5), apes (p<10 −4 , χ 2 = 446.2), bites (p<10 −4 , χ 2 = 267.1) and wounds to the upper part of the body.
As shown in Figures 3A,B and Table 2 , while both gO GT1c cysteine mutants, gO GT1c-C218S and gO GT1c-C343S, displayed a similar infectivity for HFFs as their parental strains GT1c_1 and GT1c_2, the mutation of C336S in gO GT4 led to reduction in infectivity, which was significant when compared to GT4_1 ( p = 0.0025) and highly significant when compared to GT4_2 ( p < 0.0001).
All in all, a comparison of ALDH1+ with ALDH1− cells sorted from primary, early, and late MRT xenografts demonstrated a highly significant tumor-initiation potential (p < 0.0001; 19/21 injections of ALDH1+ cells formed tumors in comparison with 2/21 injections of ALDH1− cells).
At the local scale, analysis revealed a highly significant isolation-by-distance pattern when all areas were tested jointly (r 2 = 0.069; Mantel test p < 0.0001; Figure 5 ).
The species did occupy a rather narrow extent of the gradients (with lower and upper thirds for Ellenberg indicator values for light at 6.7 and 7.4, respectively; for moisture at 4.4 and 5.3; and for nitrogen at 5.4 and 6.9), but interspecies differences in habitat preferences according to EIVs (tested using ANOVA without phylogenetic correction) were highly significant ( p <0.0001) and relatively strong (ca. 50% variation in EIVL/EIVM/EIVN explained by species identity).