Barely Significant

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highly significantP <0.00010.0× alphaqualifiedgold
These results were further confirmed in a follow-up analysis at 10 years, which found that the Recurrence Score continued to be a highly significant prognostic marker for recurrence in both N0 and N+ EBC ( P <0.0001). 29 Consistent results across multiple studies support the Recurrence Score as a prognostic indicator for DR for tamoxifen-treated patients with N+ EBC.
highly significantp <0.00010.0× alphaqualifiedgold
For human genes, highly significant differences were found between G1 and G2 (F = 1.29; p <0.0001), G1 and G3 (F = 1.33; p <0.0001), or G1 and G4 exons (F = 1.33; p <0.0001), while none was found between G2 and G3 (F = 1.04; p = 0.4254), G2 and G4 (F = 1.03; p = 0.4285), or G3 and G4 exons (F = 1.00; p = 0.9243).
highly significantP < 0.00010.0× alphaqualifiedgold
A prespecified subgroup analysis (see Supplementary material online , Figure S6 ) demonstrated a highly significant interaction (χ 2 = 19.93; P < 0.0001), with a larger treatment effect in non-China studies (RR 1.30; 95% CI 1.23–1.38; I 2 = 0.0%) compared with China-based studies (RR 1.12; 95% CI 0.96–1.29; I 2 = 0.0%).
highly significantP < 0.00010.0× alphaqualifiedgold
The maximum cross-sectional areas for those presynaptic to the NK1r cells varied from 0.16–4.38 μm 2 (median 1.44 μm 2 , n = 309), while the corresponding values for those presynaptic to the PKCγ cells ranged from 0.17–2.71 μm 2 (median 0.61 μm 2 , n = 280), and this difference was highly significant ( P < 0.0001, Mann–Whitney U -test).