Barely Significant

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highly significantP < 0.0010.0× alphaqualifiedgold
42 – 50 In a head-to-head randomized clinical trial in patients with relatively low baseline glycemic values (mean HbA 1C 7.3%, fasting plasma glucose [FPG] 9.2 mmol/L [165 mg/dL]), patients inadequately controlled on metformin who were randomized to vildagliptin 50 mg bid were weight stable at 52 weeks (−0.2 kg), which was highly significant compared with the weight gain seen in the comparator group receiving glimepiride ≤6 mg daily (between-group difference −1.8 kg, P < 0.001). 41 This difference presumably stems in part from the glucose-dependent “fail-safe” system that prevents even elevated incretin levels from overstimulating insulin secretion in the absence of elevated or rising glucose levels.
a positive trendP < 0.0010.0× alphagold
Data about laparoscopic procedures was available only after the year 2000: 48% of the patients were operated with the laparoscopic technique with a positive trend during the years, starting from 26% in 2000 to 68.8% in 2013 (AAPC 5.2, P < 0.001) (Figure 3A ) and with a mean length of stay of 4.47 ± 2.66 d (compared to 5.43 ± 2.94 with the open technique, P < 0.001).
highly significantP < 0.0010.0× alphaqualifiedgold
Because coextinctions target different phylogenetic and functional groups and given the fact that we observe a highly significant phylogenetic signal across all functional traits ( P < 0.001 in all cases), one could conclude that the functional dendrogram ( Fig. 4B ) merely depicts phylogenetic relationships ( Fig. 4A ).
highly significantp < 0.0010.0× alphaqualifiedgold
4.5.3 Spatial clustering of the vulnerability of grid cells across the protected area Spatial autocorrelation analysis (Global Moran's I) of grid-cell vulnerability index values showed highly significant (z-score >19.62, p < 0.001) positive spatial correlations (I = 0.68) across the HFPA, meaning that neighboring grid cells exhibit similar vulnerability index values more often than expected by chance.
highly significantp < 0.0010.0× alphaqualifiedgold
Gender distribution showed no significant difference between the two groups ( p = 0.6243), while prognostic status showed highly significant differences between the two groups ( p < 0.001), directly validating the prognostic prediction capability of the risk score model.
highly significantP <0.0010.0× alphaqualifiedgold
The area percentage of the collagen fibers& optical density of TNF α Semiquantitative assessment of the AP of the collagen fibers and the OD of TNF-α immunoreaction mean values in MT-stained and TNF-α immunostained tongue sections displayed a very highly significant statistical difference between the groups ( P <0.001) by using a one-way ANOVA and LSD post-hoc test.