“a decreasing trend”

Subgroup analysis for PROs At W52, the mean DLQI score showed an increasing trend with the increase in times of treatment interruption ( P <0.001), and achievement rates for DLQI 0/1 showed a decreasing trend ( P =0.007).

Results of the repeated-measures ANOVA revealed that the VAS score was lower in the observation group than that the control group, and the difference was statistically significant (intergroup effect: F = 18.888, P < 0.001), which demonstrated a decreasing trend with time (time effect: F = 956.781, P < 0.001), and an interaction effect was observed between group and time (interaction effect: F = 16.445, P < 0.001).

For laboratory findings, levels of LDH, WBC, Cr, BUN, and CRP were significantly elevated in higher NMLAR quartiles, while Alb levels showed a decreasing trend (all p < 0.001).

There was a decreasing trend in the incidence rate over time (p < 0.001), from 173.0 in 1998–1999 to 50.9 in 2006–2007.

Herbarium study: chronic OA response Herbarium-derived calcification values (n = 79) showed a decreasing trend in the calcified surface of P. pavonica thalli over time ( Figure 4A ; P<0.001, power = 1.000).

However, the magnitude of this relationship demonstrated a decreasing trend as EC increased, with effects of 0.83 ( p < 0.001) at low EC, 0.72 ( p < 0.001) at medium EC, and 0.59 ( p < 0.001) at high EC (see Table 3 ).

These results were consistent with the findings from Western blotting.Similarly, IHC analysis demonstrated a significant increase in p62 expression from 1 week to 2 weeks of age ( p < 0.001), peaking at 2 weeks of age, and then exhibiting a decreasing trend from 2 weeks to 8 weeks of age ( p < 0.001) ( Figure 5 D).

Results There was a decreasing trend in mammography screening rate for the 40-49-year age group between 2013 and 2020 (Annual Percentual Change- APC= -10.79; p < 0.001), and stability in 2020–2022.

While GSH-Px showed a decreasing trend ( P < 0.001) as the transport duration increased (1.44 vs. 1.21 vs. 0.06 vs. 0.04 μmol/mg Hb for T1, T2, T3, and T4, respectively).

Periodontal Severity and COPD Exacerbations Figure 2 shows the association between lung function parameters (post-bronchodilator FEV 1 percent predicted, FVC percent predicted, and FEV 1 /FVC ratio) and periodontitis severity, which showed that an increase in periodontitis severity and lung functions followed a decreasing trend even after adjusting for smoking (in pack-years), which was statistically significant ( p < 0.001).

As shown in Figure 4 a,f, Bcl-2 showed a decreasing trend after 6b administration, and the ratio between the Bax/Bcl-2 proteins showed an increasing trend, indicating that 6b possesses the effect of promoting apoptosis (*** p < 0.001).

Among males, the ASIR of cancer attributable to smoking showed a decreasing trend in the 40–49 age group ( P < 0.001) and an increasing trend in the 60–69 age group ( P < 0.001).

Joinpoint regression analysis showed an increasing trend from January to May for the whole population (APC = 22.7%, 95% CI: 8.2–39.2%, P = 0.006) and a decreasing trend from May to December (APC = -19.1%, 95% CI: -23.3% ~-14.7%, P < 0.001).

In terms of age, the SOCQ-general, ‘friends’ and ‘work/studies’ showed a decreasing trend (p<0.001), ‘acquaintances’ showed an increasing trend (p<0.001), and ‘family’ did not show differences among age groups (p = 0.333). ‘Social satisfaction’, measured by the VAS, did not show significant changes either by sex (p = 0.217) or by age (p = 0.262).

4C ), there was evidence for a decreasing trend in eGFR as age increased in those resolved PKD1 cases (sex adjusted: β = −1.99, P < .001) and in those unresolved cases (sex adjusted: β = −1.83, P = .014).

In RG and IS, we furthermore observed a decreasing trend of aerobes and facultative anaerobes ( p < 0.001 and p = 0.002, respectively) and an increase of anaerobes during the observational period ( p < 0.001 for both, Figure 6 ).

The average age showed a decreasing trend from T1 to T3 (68.25 ± 8.21, 63.51 ± 8.65, and 60.74 ± 8.90 years, respectively; P < 0.001).

Those with moderate to severe OSA showed an increasing trend in blood glucose levels after sleep onset, whereas those without or with mild OSA showed a decreasing trend (F = 8.933, p < 0.001).

The survival probabilities for the highest and lowest METS-VF groups, as depicted by the Kaplan-Meier curve, exhibited a decreasing trend with prolonged follow-up (log-rank test, p < 0.001).

Results The urine cotinine concentration tended to decrease every year (2.91 ng/ml in 2009, 2.12 ng/ml in 2010, and 1.31 ng/ml in 2011), showing a decreasing trend ( P < 0.001).

Years of education showed a decreasing trend across groups, with the dementia group having the lowest educational attainment ( F = 40.89, p < 0.001).

The ASIR demonstrated a decreasing trend (AAPC = −0.338, 95% CI: −0.362 to −0.314, p < 0.001) ( Supplementary Table S7 ).

Interestingly, spontaneous labor showed the highest incidence in underweight women with a decreasing trend observed as BMI increased ( P <0.001).

Trend of birth weight change The trend of neonatal BW change from 2015 to 2021 was between 3250 (2346–4100) g and 3300 (2300–4100) g, with a decreasing trend of BW year by year (Z=105.881, p<0.001).

Results 2005–2016, cancer mortality in the elderly in China showed a decreasing trend (AAPC = -1.2%, P <0.001).