muciniphila significantly reduced the increased DCA and LCA levels and showed a decreasing trend in TDCA levels ( p = 0.08, Figure 7B ).
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In terms of the changes of glycosylated hemoglobin in different weight loss points, T1 to T3 time point showed a decreasing trend, but with no statistical difference (p = 0.08),the changes of T4 and T3 had statistical significance (p = 0.01) and had statistical significance (p = 0.01) compared with that before weight loss.
The anti-inflammatory cytokine TGF-β showed a decreasing trend after 21 days of spleen ( p = 0.08; Fig. 5 H), while there was a remarkably higher than control group in the head-kidney on 35th day after immunization ( p < 0.01; Fig. 6 H).
In contrast, blood T 3 concentration increased with Se supplementation (RMD = + 0.17 ng/mL; 95% CI: +0.08, + 0.26; p = 0.0002) compared to the control mean (1.52 ng/ml), while T 4 concentration showed a decreasing trend (RMD = -0.47 μg/dL; 95% CI: -0.99, + 0.06; p = 0.08).
Simultaneously, the CA group showed a decreasing trend in NDFom and hemicellulose content ( p = 0.08; p = 0.09).
However, in 12-week-old turkeys, a decreasing trend in α diversity was observed ( P = 0.08) in the S group with SH inoculation, potentially associated with an increased inoculum level (10 8 CFU/bird) used in the 12-week-old turkeys compared with their 7-week-old counterparts (10 6 CFU/bird).
approached significancep = 0.08
Only the question “In general, how often do you take your PrEP?” showed a decreasing trend that approached significance, with fewer participants reporting they took their PrEP “all of the time” (z = − 1.74, p = 0.08, details in Supplemental Table).
Similarly, lovastatin had little effect on rumen fermentation characteristics except that the proportion of propionate increased, which led to a decreasing trend (P<0.08) in acetic: propionate ratio with increasing dosage of lovastatin.
In addition, we observed a decreasing trend of the seizure severity score in the MCC‐135 treatment group (especially in the dose group of 100 μg/kg/d, p = 0.08) (Figure 4C ).
A decreasing trend in diversity was observed from day 1 (control) to day 5 (control, p = 0.08), whereas no significant difference between day 1 (control) to day 5 (antibiotic treated) ( p = 0.32).
As shown in Figure 7 C,D, busulfan significantly down-regulated the mRNA levels of the oxidative stress-related genes Nrf2 , SOD , and Gpx1 ( p < 0.05) and had a decreasing trend in CAT ( p = 0.08).
We observed a significant decrease in P-gp protein/ ABCB1 mRNA and BCRP protein ( p < 0.05) from early to mid-gestation ( Figure 7 B–D), whereas there was a decreasing trend in ABCG2 mRNA expression ( p = 0.08) ( Figure 7 E).
We found a positive trend ( F = 0.20, p = 0.65) in corneal densitometry despite the use of HPCS, with a decreasing trend ( F = 3.30, p = 0.08) after switching to Cystadrops ® .
Similar to what was observed in pseudoglandular stage, canalicular stage HFLF displayed a decreasing trend of ACTA2 expression when treated with FGFR2 siRNA and rhFGF18 ( p = 0.08; Figure 2B ), whereas FGFR3 siRNA combined with rhFGF18 showed no change.
Although it was not statistically significant, we also observed a decreasing trend in spontaneous inhibitory charge transfer in Scn8a D/+ mice (–20,424 ± 4,895 pA × s; P = 0.08; Figure 5E ). sIPSC recordings include both AP-induced synaptic transients as well as mIPSCs, which occur because of spontaneous vesicle fusion in the absence of an AP ( 48 , 49 ).
However, although we could observe a decreasing trend of HOMA-IR index after BBR treatment, it has no significant difference compared with the model group [ SMD = 2.75, 95% CI (−0.35, 5.85), p = 0.08] ( Table 1 and Supplementary Figure S6C ).
Muscle Activity As shown in Figure 6 , the average muscle activities of target semitendinosus (ST) and gluteus maximus (GM) showed a decreasing trend (two-sided paired t -test, p = 0.08, p = 0.08) but not a significant reduction during the whole gait cycle compared to that in the NE_W condition.
Intestinal Permeability There was no significant difference in plasma DAO levels among the groups after 6 weeks of experimental treatment ( P > 0.05; Table 6 ); A decreasing trend in plasma D-LA levels was observed in the LCP-MAA group compared with the LCP-CAA group ( P = 0.08), but the plasma D-LA levels were not significantly different from those in the CON group ( P > 0.05).
Repeated exposure to the nonalcohol context without cues or alcohol caused a decreasing trend in total port entries across sessions (Session, F (7, 105) = 2.32, P = 0.08).
Regarding the BMT, amygdala activity to quickly-presented happy and fearful faces did not significantly change after neurofeedback, although a decreasing trend could be observed, F (2,46) = 2.74, p = .08, eta 2 = 0.11 (see Fig. 8B ). 3.6 Correction for multiple testing We repeated analyses on primary endpoints (ZAN-BP and DERS total score, emotion-modulated startle, resting HRV, amygdala reactivity to EWMT and BMT) using a Bonferroni-corrected alpha-level of p = .008.
LDL cholesterol showed a decreasing trend by 5.9% (baseline: 118.6 mg/dL (23.5); intervention: 111.6 mg/dL (19.6); p = 0.08), and triglyceride levels were not changed ( Figure 2 ).
In addition, a decreasing trend in the probability of NC was observed when iPTH (at 28 days of life) increased (OR (based on 10 units change) 0.911, 95% CI 0.834–0.994, p = 0.08) ( Figure 4 ).
In AMO-1 cell line, compared with normal control group, overexpression of SDHA showed a decreasing trend in cell invasion (Fig. 1C , P = 0.0808).
There was a significant group × time interaction in MSNA frequency and incidence ( P = 0.022 and 0.023, respectively; Figure 2 ) with a decreasing trend in Exercise group (33.5 ± 11.8 [95%CI, 27.6–39.2] to 28.1 ± 12.5 [95%CI, 22.1–34.1] bursts/min, P = 0.111; 54.4 ± 19.1 [95%CI, 44.8–64.0] to 44.9 ± 21.5 [95%CI, 34.5–55.3] bursts/100 heart rate [100HR], P = 0.054), but an increasing trend in Stretching group (30.6 ± 10.6 [95%CI, 24.1–37.1] to 36.0 ± 10.4 [95%CI, 29.4–42.6] bursts/min, P = 0.081; 50.2 ± 18.1 [95%CI, 39.6–60.9] to 57.7 ± 18.3 [95%CI, 46.2–69.2] bursts/100HR, P = 0.165) after 12 weeks.
Notably, Prdm1 mRNA showed a decreasing trend at 48 h (n.s., p = 0.081) and was significantly reduced at 72 h in Abcd1 -deficient CD4 + T cells compared with wild-type cells ( Figure 4B ).