“a favorable trend”

No significant improvements were observed between the With- and Without-ICI groups in OS and ORR meta-analyses, but the With-ICI group had a favorable trend in OS.

Nonetheless, a favorable trend was observed.

SOD also showed a favorable trend (SMD = 1.02; 95% CI: −0.84 to 2.88), although with wide variability and a lack of statistical significance.

The pooled RR was 0.72 (95% CI: 0.46-1.14), indicating a favorable trend toward the repair group, though the difference was not statistically significant (p>0.05) as shown in Figure 7 .

The main findings of our analysis were: (1) the number of patients with resolution of symptoms was not significantly different between groups; (2) recovery and symptom alleviation rates showed a favorable trend in patients receiving 3CL protease inhibitors compared to placebo; (3) 3CL protease inhibitors significantly reduced the viral load from baseline as compared with placebo and (4) were associated with higher risk of any adverse events (40.24% vs. 31.26%).

The 55% and 60% groups showed a favorable trend in smaller prescription isodose volume spillage; however, no significance was observed in other evaluation metrics.

The studies evaluated buccal gingiva levels when placing the IIP with and without CTG, obtaining a mean buccal gingiva level difference of 0.09 mm (95% CI: −0.54 to 0.72, p = 0.05), statistically not significant, but with a favorable trend.

There was a favorable trend in survival in the experimental arm; however, the EFS outcomes were still immature [HR 0.76; 95% confidence interval (CI) 0.40–1.44] after a follow-up of 20.6 months [ 14 ].

Although intervention within 24 h showed a favorable trend in severe cases, it did not significantly improve outcomes compared with 24–72 h. status released display-pdf yes is-in-collection-domain yes is-olf no is-manuscript no is-preprint no is-journal-matter no is-scanned no is-retracted no Revised 2025 Apr 23; Received 2025 Mar 9; Accepted 2025 May 9; Issue date 2025 Aug. 1.

In contrast, the Kaplan–Meier analysis of PFS showed no statistically significant difference across AE subgroups (log-rank p = 0.14), though a favorable trend was observed.

Conclusions Patients submitted to endomanometric LNF showed a favorable trend toward better symptoms control, decreased postoperative complications, better satisfaction, and higher PPI discontinuation compared with those who underwent LNF alone.

The trial demonstrated a favorable trend toward better safety profiles and neurological outcomes in the CS group, particularly regarding early post-procedural assessment [ 4 ].

Specifically, remdesivir showed a significant reduction in hospitalization and respiratory failure, while for ICU admission and mortality, there was a favorable trend, although the wide confidence interval and lack of statistical significance suggest insufficient evidence.

We conducted an analysis with varying cutoffs to examine whether there was a favorable trend in PFS and OS in the EA group, even with different proportions of infusion cutoffs.

In that study, the 3-year PFS rate was 66.3% in the group that received DOS therapy and 60.2% in the group that received surgery plus postoperative S-1 therapy, indicating a favorable trend for the preoperative group [ 9 ].

Due to the presence of confounding factors (stability mainly due to the cortical component) in this early healing phase, a significant advantage in the use of bioactive surfaces is not detectable, even if a favorable trend is apparent.

Conclusions Although a favorable trend is emerging, pooled data suggest that within the early treatment period (<12 weeks), BoNT-A may not be more effective than a placebo in reducing pPSS.

Among the studies included in this systematic review, only one study failed to achieve statistical significance in adverse event reduction; however, a favorable trend with dose reduction was reported [ 18 ].

In many subgroups, surgical resection had a favorable trend to improve survival compared to chemotherapy, especially in patients with poorly differentiated histology (HR [95% CI] 0.30 [0.11–0.83]), solitary clinical PALNM (0.33 [0.17–0.64]), or the presence of concurrent distant metastasis (0.34 [0.18–0.63]).

In addition, although quadriceps torque showed a favorable trend in the EAA group, the difference was not statistically significant.

CONCLUSIONS The study has demonstrated safety and feasibility of repeated infusions of MTX110 via CED in DMG patients with a favorable trend in overall survival warranting further trials with higher number of infusion pulses. status released display-pdf yes is-olf no is-manuscript no is-preprint no is-journal-matter no is-scanned no is-retracted no Collection date 2024 Jun.

Despite the lack of statistical significance, this observed reduction reflects a favorable trend toward improved microvascular outcomes with semaglutide and is clinically relevant, as the prevention of microvascular outcomes is a critical concern in the management of T2D.

Furthermore, the network meta‐analysis suggests a favorable trend with MT treating ULVP as supported by the VHI outcomes.

We found that mFOLFIRINOX was associated with significantly improved disease-free survival and a favorable trend toward better overall survival, independent of histological subtype.

The results showed a favorable trend in OS in the preoperative CXRT group, although there was no statistically significant difference in either 3-year or 5-year OS rates because of the small number of enrolled patients [ 20 , 21 ].