Barely Significant
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“a favorable trend”

1,336 sentences · 1,336 papers · 2,253 search hits before verification · confirmed specimen

Sighted at

p=0.09

Listed by Hankins (2013) · Otte et al. (2022)

In the literature

3 The idea that sex steroids are involved in MS and that they might be a therapeutic option also originates from retrospective studies revealing that pregnancy has a favorable trend for the course of MS on a short- and long-term basis. 4 Remission of symptoms is seen during pregnancy, in particular during the last trimester when estrogens and progesterone plasma levels are at their maximum. 5 Postpartum, MS symptoms exacerbate again. 4 Recent reports, however, have shown that
However, the results of the included studies are insufficient to indicate a favorable trend from the effects of BFR in the long term and follow-up; therefore, future studies are required to evaluate these periods in order to demonstrate whether its effects are maintained or improved with respect to high-load or aerobic exercises.
The first interim analysis, at a median follow-up of 17.9 months, showed a statistically significant improvement in PFS (24-month PFS was 67.8% with pembrolizumab + CCRT versus 57.3% with placebo + CCRT) and a favorable trend in OS (HR = 0.73) for the combination pembrolizumab and CCRT compared with placebo and CCRT, with a manageable safety profile.