Barely Significant
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a favorable trend

994 sentences · 994 papers · 2,147 search hits before verification · confirmed specimen

Sighted at

p=0.09

Listed by Hankins (2013) · Otte et al. (2022)

In the literature

Conclusions: The addition of CDK4/6i to ET improves iDFS and shows a favorable trend in DRFS in early-stage HR+/HER2− breast cancer, highlighting the need for longer follow-up to clarify their long-term benefit. early-stage HR+/HER2− breast cancer CDK4/6 inhibitors endocrine therapy adjuvant therapy meta-analysis invasive disease-free survival abemaciclib ribociclib palbociclib Thi
Subgroup analysis of PFS by demographics and baseline characteristics revealed a favorable trend for arm A and arm B versus arm C in most subgroups, with some exceptions; however, this should be treated with caution because of the small sample sizes ( Supplementary Fig. 2 A and B ).
Notably, for SCLC patients with LM, a subgroup historically associated with limited treatment efficacy, even a modest extension in PFS may translate to meaningful symptom alleviation and could potentially signal a favorable trend in OS.
CONCLUSIONS The study has demonstrated safety and feasibility of repeated infusions of MTX110 via CED in DMG patients with a favorable trend in overall survival warranting further trials with higher number of infusion pulses. status released display-pdf yes is-olf no is-manuscript no is-preprint no is-journal-matter no is-scanned no is-retracted no Collection date 2024 Jun.