Over the 4 study years, we noted a possible trend of decreasing utilization of ICI monotherapy, which could be attributable to decreased patient numbers in 2020 or secondary to an increase at our academic center in ICI-based clinical trial options that enrolled immunotherapy-naïve patients, who were thus excluded from this observational study.
P values 0.05 < P < 0.10 were considered a possible trend towards effective treatment.
0%, p=0.06), suggesting a possible trend toward more severe disease at baseline.
Although the difference was not statistically significant, the incidence was lower in the Belimumab group, suggesting a possible trend toward a protective effect.
This suggests a possible trend that women's physiological functioning when discussing relationship issues may be enhanced by talking about romantic trials more frequently with partners and less frequently with friends.
One study showed level III evidence for potential antibiotic resistance when the antibiotic was administered for greater than 1 month, and four level III studies showed a possible trend towards increased moxifloxacin and ciprofloxacin resistance.
Although this result was not statistically significant, the p -value approached the conventional threshold, indicating a possible trend toward increased risk.
23 , 24 RATKA may be a possible trend in the growth of joint surgery. 25 , 26 Most recently, a novel real-time robotic-assisted system for RATKA named HURWA has been developed. 27 The system is semi-active, employing a computer platform and a robotic arm with a power system.
Notably, ERBB4 mutations were observed in 5.8% of H/L patients compared to 2.3% of NHW patients ( p = 0.1077), and IGF1R mutations were detected in 7.2% of H/L patients versus 2.9% of NHW patients ( p = 0.07798), indicating a possible trend toward increased RTK pathway activation in H/L patients.
In any case, these correlations are not statistically significant, and we consider them at best as indicative of a possible trend.
The most pronounced increases were observed among adults aged 18–34 and individuals with lower household incomes, suggesting a possible trend of self-directed use for mental health purposes [ 62 ].
Given the small sample size of 15 years in trend analysis, small P values reported should be treated as indicative of a possible trend.
The mean difference in 6MWT distance from pre to post was 22 (SD 52; t 8 =1.3; P =.24; 95% CI −17.7 to 61.8), indicating a possible trend toward improvement but no statistically significant change across time.
The mean age at diagnosis for the CCMP group in our study was slightly higher (7.00 years) than the overall cohort (6.39 years), suggesting a possible trend towards older age at diagnosis being linked to a higher CCMP risk, although age was not a statistically significant factor in our analysis.
Conversely, pseudoword reading ( β = −0.041, p = 0.579) and text comprehension ( β = −0.038, p = 0.673) exhibited slight negative beta values, indicating a possible trend where certain neonatal complications might be weakly associated with poorer reading outcomes, although the effect sizes remain small and non‐significant.
Fish fed untreated SBM had a possible trend for increased reactive behavior (lower repeatability), which may indicate negative implications for their welfare.
Highlight box Key findings • Systemic treatment patterns and outcomes of intermediate and advanced Canadian hepatocellular carcinoma (HCC) patients appeared to be comparable, with a possible trend towards better progression-free survival and overall survival in intermediate stage patients.
Similarly, no significant association was found between relapse and NHL localization (Fisher's exact test, P = 0.086), although a possible trend towards more relapses in the extranodal group was noted.
[ 14 ]) indicated a possible trend towards lower TNF-α levels in the probiotic group compared to placebo, although heterogeneity remained substantial.
For example, psychological difficulties (such as high anxiety or emotional stress during pregnancy) had an OR of 1.76 (95% CI: 0.75-4.14) for subsequent PPD, suggesting a possible trend, but our sample size was too limited to confirm it.
The observed differences in hearing loss across DR-TB types suggest a possible trend, with higher rates among pre-XDR patients.
However, treatment of an established infection with phage-loaded hydrogels showed a possible trend of bacterial load reduction, but no superior effect to the antibiotic treatment alone.
Although not statistically significant, the near-threshold p -value for planned roll ( p = 0.060) suggests a possible trend that may reach significance in larger studies.
0.17 ± 0.07 ng/mL in non-catheter UTIs, hinting at a possible trend but not meeting the significance threshold.
Biochemical measures revealed a possible trend for iron accumulation in the cerebellum and decreased levels of iron within the CSF and plasma of patients with type C1 disease [ 85 ].