“a significant trend”

A significant trend was found between daily caffeine dose and ACT subscores of consistency, 2-h pain free response, functioning, and the total score (p for trend = 0.001, 0.001, 0.003, and 0.001), but not in the emotional assessment (p for trend = 0.161).

A significant trend of differentiation between the critical and ordinary groups was found from the PCA chart ( Figures 3D – F ), and some samples could not be distinguished from the ordinary group, indicating that there was a certain difference in the metabolic level between the severe group and the ordinary group, and some samples were similar to those from the ordinary group.

Estimates for x1 and x2 indicated whether a significant trend change occurred.

The positive network only showed a significant trend when predicting ΔT1 ( ρ = 0.31, P corr = 0.071).

The results showed a significant trend in the influence of MEL on the FW and DW of cultures ( Figure 3 ).

Trend test analysis (P for trend < 0.001) in all models showed a significant trend.

Given the small samples for some compound genotypes we instead examined the white spotting phenotype compared to the total number of white spotting alleles, regardless of the number of contributing loci, and could not evaluate interactions between specific loci Nonetheless, a significant trend for an increase in the white spotting phenotype with an increase in the number of non-reference alleles was apparent in this dataset ( Table 4 and Figure 2 ).

On the other hand, the CANTOS trial has shown that the inhibition of IL-1b with canakinumab was followed by a significant trend for a dose-dependent reduction in the incidence of the composite endpoint of hospitalization for heart failure and heart failure-related mortality [ 75 ].

A significant trend toward lower levels of post-discharge consultations was observed over the 15 years of the study (2002–2017).

The HRs for cardiovascular mortality declined with increasing DI-GM levels compared with the lowest category (i.e., DI-GM ≤ 3), being 0.887 (95% CI 0.630–1.249, for DI-GM = 4), 0.793 (95% CI 0.482–1.305, for DI-GM = 5), and 0.724 (95% CI 0.535–0.979, for DI-GM ≥ 6), with a significant trend observed (P for trend < 0.05).

This study was discontinued early by the independent ethics review panel because of a high number of serious adverse events and deaths in the placebo arm, and a significant trend toward improvement in PFS in the treatment group ( 58 ).

These events lead to cross-linking of collagen and elastin, making it less degradable.[ 6 , 15 , 24 , 26 , 27 ] A significant trend was observed with gradual decrease in serum iron level as the clinical stage and histological grade of OSMF increased.

As expected, we found a significant trend correlating SNP density with the progression of DNA replication ( Figure 2A ).

Moreover, there was a significant trend of increasing scores in line with higher high school academic rankings prior to entering university.

However, across the Q1 through Q3 quartiles, a significant trend was observed at the 10% level for both hypertension and asthma ( table 2 ).

Subsequent pairwise Wilcoxon rank-sum test revealed a significant trend of increased knowledge and attitude scores in respondents with knowledge sources that are either physicians or books and magazines when compared to respondents with other sources (p < 0.05, Figure 2B , 2C ).

In the size‐based analyses for this species, there was a significant trend of greater clustering around conspecific adults by 1‐ to 5‐cm DBH stems as compared to 5‐ to 10‐cm DBH stems, and there was a comparable trend of slow‐growing saplings clustered around conspecific adults in the growth‐based analyses.

Moreover, a significant trend was observed toward increase in childhood obesity with the worsening of food insecurity (P dose–response = 0.007).

The feed rate parameter has a significant trend of thrust force increase.

At the same time, there is often a significant trend of synergistic changes in the percentage of processing trade and the percentage change of trade in high-tech products.

This is the first study reporting a significant trend in TF and patient survival improvement throughout the vintages in a developing country and after adjusting for multiple covariates.

A significant trend of decreasing ORs for intermediate AMD associated with increasing Varied staple food diet scores was noted ( p for trend = 0.002).

Besides, mild-moderate HHcy [(HCy): 10–100 μM] is an independent risk factor commonly causing cognitive impairment in older adults ( 40 ) and a significant trend for an association between severity of dystonia and homocysteine has been reported ( 41 ).

DSP alleviates the inflammatory response It can be seen from ( Supplementary Table S3 ) that in the first week of modeling, there was no difference in body weight among rats in each group; by the fourth week, the body weight of rats in the model group was significantly lower than that of rats in the control group ( p < 0.01), and the DSP group showed a significant trend of recovery.

A significant trend was observed, indicating that the number of family risk factors is positively correlated with PSU risk ( P for trend < 0.001).