“a significant trend”

There was a significant trend difference between the intervention and control populations in all forms quarterly TB notification rates (1.007, 95%CI 1.003–1.011, p = 0.001), as well as significant level change difference (1.036, 95% CI 1.014–1.059, p = 0.001).

However, we observed a significant trend in increases in CTX and P1NP ( p < 0.001) over time in all 3 arms.

Of these, the ucRT group exhibited a predominant first site of progression extracranially, whereas the non-ucRT group showed a significant trend towards intracranial progression as the initial site (P < 0.001; Figure 6 ). 3.6.

Additionally, compared to no use of tobacco nor vaping, exceeding the guidelines was significantly more common among men and women who only vape, who only smoke, or those who vape and smoke with a significant trend ( p < 0.001) for men.

Cumulative incidence of people with severe COVID-19 showed a significant trend in decreasing proportion as the variant progressed (Cochran-Armitage test for trend, P < 0.001).

A significant trend in knowledge score was observed with an increase in the level of education ( p < 0.001), with an effect size of 0.092.

There was a significant trend towards increases in the volumes contoured when using MRI and PET/CT, compared to MRI alone (Z = −4.53, p < 0.001).

There was a significant trend (Spearman’s ρ = -0.66, N = 33, P<0.001) for villages with lower kdr frequencies in 2017 to show a higher increase over subsequent years ( Fig 3 ).

We observed the prevalence of long COVID to increase with advancing age, with a proportion of 10.0% (7 out of 70) in the 18 to 24 age group, 29.4% (74 out of 252) in the 25 to 49 age group, and 34.4% (52 out of 151) in the 50 to 64 age group, with a significant trend for age ( p = 0.0010).

Among the total population sample, there was a significant trend for an increase in NVT carriage over the survey years in the rural site (Chi squared test for trend p < 0.001) and but not in the urban site (Chi squared test for trend p = 0.36).

A significant trend toward a higher clinical success rate was noted in the group undergoing prophylactic angioembolization (100% vs. 82.1%; p = 0.001).

In the PENS-Diet group, the median values received a score of 2 (range 1–4), representing a significant trend towards constipation ( p < 0.001).

Concentration of ctDNA was significantly different between stages of disease [ H (3) = 15.307, p = 0.002], with a significant trend of increasing ctDNA concentration associated with more advanced disease at diagnosis defined by NCCN clinical stage ( J = 1103.5, z = 3.737, p < 0.001, r = 0.46) (Fig. 2 ).

There was a significant trend that treatment in asymptomatic patients increases with colony count in urine culture (p< 0.001).

A significant trend in the implementation of the HBCR programs in two groups was shown using chi-square test and independent t -test and variance with repeated measurements ( p < .001).

There was a significant trend towards higher ISS in the HEMS group compared EMS in the cohort overall, as well as within each separate injury severity group (p < 0.001) (Fig. 3 , Table 1 ).

Further, the number of sickle-shaped blood vessels was associated with distant metastasis and OS, with a significant trend toward a poor prognosis (metastasis P < 0.001, Cox; OS P < 0.001, Cox) observed for patients with more than 100 such vessels in large maximal tumor sections.

However, at postoperative day (POD) 1, there was a significant trend toward an increase of albumin, hemoglobin and calcium in the ERAS group compared with the control group ( p < 0.001), which continued at POD 3 ( p < 0.05).

Using a generalized additive mixed model (GAMM 51 ), which accounts for the temporal structure within the data by specifying a correlation structure (corAR1), we test for change in the estimated size of the projected potential climatic niche space through time, from 145 ka to 30 ka ago and find a significant trend ( r 2 = 0.373, edf = 2, p < 0.001), in which as time progresses, there is a general pattern of contraction from the Eemian onwards (Fig. 5 ).

There was a significant trend that the longer the duration of drug use, the higher the improvement rate relative to 11% with < 30 days of use ( p < 0.001).

Post hoc analyses revealed a significant trend of SSI score reduction (t=5.45, p<0.001) from T1 to T5 in HDRS responders but not in non-responders (t=−0.66, p=0.524).

There was also a significant trend towards lower UCT scores in patients receiving a higher number of current medications ( p < 0.001 for decreasing trend).

We did not find a significant trend of Preseason T SD with latitudes ( Fig. 3 b), but there was an increase in MAT SD with latitude at a rate of 0.09 ± 0.02 °C °N −1 (P < 0.001, Fig. 3 a).

Consistently, when RDW was assessed as quartiles, compared with the reference group (quartile 1, RDW ≤12.4%), the HRs of recurrence of ischemic stroke was 1.372 (95% CI=0.671–2.805, P=0.386) in quartile 2 (12.8%≥RDW>12.4%), 1.835 (95% CI=1.222–2.755, P=0.003) in quartile 3 (13.3%≥RDW>12.8%), and 1.732 (95% CI=1.114–2.561, P<0.001) in quartile 4 (RDW>13.3%), with a significant trend test (P<0.001) after adjusting for covariables.

There was a significant trend in increasing mortality risk across troponin categories in all three subgroups ( p < 0.001).