However, a significant trend was noted where the proportion of individuals with high LDL-PRS increased with rising LDL-indicating a polygenic component at play ( p = 0.01) (Supplementary Fig. 2).
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Comparison of the distribution of SCAI Shock stages revealed a significant trend towards a higher proportion of stages D (58.9% vs. 47.2%) and E (1.8% vs. 0.4%) ( P = 0.01) among the 1‐year non‐survivors.
Comparison of the distribution of SCAI SHOCK stages revealed a significant trend towards a higher proportion of stages D (64.7% vs. 25.0%, P < 0.01) among the 1‐year non‐survivors.
Indeed, there was a significant trend in increasing absolute cortical thickness from sulcal to intermediate to gyral cortices (rank correlation of individual values ρ = 0.56, p < 0.01; sulcal average: 1,747 ± 112 μm; intermediate average: 1,791 ± 90 μm; and gyral average: 2,227 ± 132 μm), confirming quantitatively previous qualitative observations [ 9 ].
A significant trend ( P < 0.01) is reported with daily amount of snuff consumed for pancreatic cancer [ 32 ] in never smokers, but this merely reflects the overall relationship, with RRs similar in light and heavy users (1.9 for 1–9 g/day, and 2.1 for 10+ g/day relative to never users).
For 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) a significant trend (p = 0.01) for the SMRs with increasing cumulative PCDD/F exposure was observed.
There was a significant trend for White patients to be more readily offered CAR-T than their non-White counterparts (offered CAR-T: 29% vs 6%; P <0.01), with BsAbs also more likely offered to White patients (offered BsAbs: 21% vs 8%; P =0.096).
When age- and sex-adjusted AGE values stratified by TBR tertiles were compared using ANCOVA, a significant trend was observed ( P < 0.01).
However, among kidney transplant patients younger than 50 years at the time of transplantation ( n = 754), there was a significant trend for increasing the occurrence of post-transplant CV complications along the consecutive KDRI quartiles (χ 2 = 7.3; p < 0.01), with the frequency of CVEs across the study groups as follows: Q1 13/205, Q2 23/179, Q3 24/166, and Q4 21/123.
The current study results consistently demonstrated a significant trend ( P < 0.01).
Although the 7 items out of 26 in the impacts domain also showed a significant trend with both lung functions (both P < 0.01; Table 4 ), these items are more diversified, not easily remembered, and thus less feasible in clinical application.
Although there was a significant trend ( P <0.01), reduction of CRC risk did not appear to be stronger with duration of HRT use.
When we grouped the patients according to their genotype and S-MBL above or below the median for their genotype (high/above [ n = 78], high/below [ n = 78], low/above [ n = 65], and low/below [ n = 66]), there was a significant trend among the four groups to predict survival free from cardiovascular event (log-rank test P = 0.01) ( Fig. 1 ).
2 a ) further supported a significant trend toward higher ω values (indicative of relaxation of selection) in lungfish (Mann–Whitney U test, P < 0.01).
The sensitivity analysis results revealed a significant trend across UACR tertiles and ACM among participants aged <80 and with no CVD history, respectively ( p < 0.01 for trend). 3.3 ROC analysis of UACR predictive value for ACM in DM The ROC analysis results demonstrated the UACR prognostic value for ACM.
The fully adjusted model demonstrated a significant trend correlating increased TTHC (P<0.01 for trend), SR (P<0.001 for trend), and Ki-67 expression (P=0.004 for trend) with ALNM.
If a significant trend was detected at p ≤ 0.01, Williams’ test was used ( Williams, 1986 ); if the trend was not significant, Dunnett’s test was used ( Dunnett, 1955 ).
In patients with zero, one, two, or three baseline panel abnormalities, there was a significant trend toward EA risk reduction among NSAID users compared to nonusers ( p = 0.01).
Notably, a significant trend of increasing mortality was observed across SDoH categories, with higher mortality rates in the high SDoH group ( P < .01).
The Cuzick extension of the Wilcoxon's rank sum test confirmed the presence of a significant trend of increasing MCM-2 and MCM-5 expression with increasing tumour stage ( P =0.0100 and 0.0300, respectively).
Compared to Q1, the Q2 and Q4 groups showed significantly reduced risk in 1-year stroke recurrence (Q2: HR = 0.46, 95% CI 0.27 to 0.79, P = 0.005; Q4: HR = 0.47, 95% CI 0.27 to 0.81, P = 0.007), with a significant trend across all quartiles ( P = 0.01 for trend tests).
Conversely, in the population of patients with sperm abnormality, we found a significant trend increase from day 1 to day 7 of TSC (16.38 vs. 56.0; p<0.01), sperm concentration (million/ml) (8.0 vs. 18.0; p<0.01) and morphology (3.0 vs. 5.0; p<0.01).
It is worth noting that the Pielou evenness index showed a significant trend of first decreasing and then increasing with increasing longitude ( p < 0.01) (Figure 3c ).
There is a significant trend (P = 0.01) in which cuticle thickness generally increases with increasing length of time to knock-down, although the correlation is weak (R 2 = 0.33).
We also found no significant interaction on the log-odds scale between PGSs and individual rCNVs, except for the 16p13.11 duplication and ADHD-PGS (β = −0.51; 95% CI, −0.86 to −0.16; P = .006), although, there was a significant trend for negative interaction coefficients (27 of 39; P = .01 in a binomial test) (eTables 11 and 12 in Supplement 2 and eTables 13 and 14 in Supplement 1 ).