The N status (N0 versus N+) showed a statistical trend of an association with the locoregional failure-free survival ( P = 0.13).
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Targeting of TFEC also attenuated LIPA expression, even though the merger of biological replicates revealed a statistical trend after correction for multiple hypothesis testing (Fig. 5e ; p = 0.14).
Additional covariates were selected using a four-step process: 1) identification of cross-sectional and longitudinal patterns in the data, 2) identification of variables which were predictors of outcome based on a statistical trend defined as a P < 0.15, 3) selection of variables that were significant independent predictors of outcome, with a P < 0.15 tolerance, and 4) assessment of the clinical relevance of the identified variables by an independent scientific advisory committee.
Parameters considered as potential predictors were those showing a statistical trend ( p < 0.150) in univariate analysis and the parsimonious model was derived using backwards variable selection at a p < 0.05 level. 3.
Significance was determined a priori at p < 0.05, and a statistical trend was defined at p < 0.150.
Second, bivariate analyses were used to identify variables which were predictors of outcome based on a statistical trend defined as a P < 0.15.
A statistical trend was defined as p < 0.15.
Malignancy showed a statistical trend (0.05 < p < 0.15).
Variables that showed a statistical trend ( p < 0.150) in the univariate analysis were considered in multivariate analysis to identify independent predictors of response.
171 days, p = 0.045; Figure 3 B), while only a statistical trend was observed for OS (150 vs. 202 days, p = 0.15; Figure 3 A).
However post hoc analysis ( Fig 4C ) revealed that the PDGF-BB treated cells remained a statistical trend (p = 0.18).
A statistically increased astrocytoma incidence was reported at 7.5 mg/mL MTBE (calculated dose: ∼333 mg/kg-bw/day) when assessed using a statistical trend test (Cochran), but not when using a pairwise comparison (Fisher’s exact test p < 0.181).
4.5 ± 2.0 p = 0.026); other factors showing an association at the level of a statistical trend were low BW ( p = 0.191) and the coexistence of IVH ( p = 0.142).
Additional analyses were completed to compare the 6-min walk distance at baseline between the dropout and completed groups; findings demonstrate a statistical trend with a 35 m higher 6-min walk distance ( p = 0.196, Cohen’s d = 0.76, 95% CI − 17 to 83 m) performed by the dropout group (302 ± 84 m) compared to the completed group (269 ± 78 m) at baseline.
To use the minimum number of animals necessary, we analyzed data once n=4~5 (or ~8 for the non-EEG/dialysis experiment) was reached, and the sample size was increased if a statistical trend (p<0.2) was observed.
However, when data were plotted, a statistical trend (P = 0.20) was observed for PDGF-BB concentrations in P-PRG from SC in comparison with ACD-B (Figure 2 ).
First, exploratory analysis based on Spearman’s rank correlation was conducted to identify independent variables that show a statistical trend ( p < 0.2) of association with the outcome of interest.
On MVA ( Table 5 ), treatment time was not associated with FFBF or FFDM when included in a model with NCCN risk category, although there was a statistical trend ( p < 0.2) for treatment time.
A statistical trend was considered for P < 0.20.
While 2uM of sorafenib alone didn't affect viability, the addition of Metformin resulted in statistically significant reduction in viability of SK-Hep-1 (p=0.029), and a statistical trend in reduction of viability in PLC/PRF/5 and HuH-7 (p=0.23, p=0.059 respectively; Fig. 1 ).
The time to adaptation was not significantly different between volumes, but it showed a statistical trend of a difference among the three strains and the interaction of strain and volume (randomization ANOVA, P = .59 for volume, P = .08 for strain, and P = .056 for their interaction).
By contrast, the rate ratio curve for male blue-collar workers showed no sign of a statistical trend (p = 0.66).
1 ), the risk of progression to dementia was significantly increased among A- MCI participants with higher compared to lower CAIDE scores (Cox aHR = 3.1, 95% CI 1.43–6.53, KM log-rank chi-square (ChiSq) = 8.1, p = 0.004), while in the A + MCI subgroup a statistical trend-level association was observed (Cox aHR = 1.3, 95% CI 0.98–1.7, KM log-rank ChiSq = 0.16, p = 0.7).
Rather, although there was only a statistical trend detected for accuracy by rich and lean trial type (main effect of defeat status: F(1,30) = 0.059, p = 0.810), as expected, control subjects had on average higher accuracy during rich trial types and lower accuracy during lean trial types relative to the jCSDS group (Fig. 4D ) which, in addition to the log b metric, is another way to characterize their increased response bias for the rich stimulus.
There was a statistical trend ( P < 0.9) for improvement in the ALIF’s LLA and the PI – LL ratio in comparison to pTLIF.