“a trend toward significance”

However, two variants on chromosome 17 showed a trend toward significance in the Sierra Leone cohort (Table 1 and Extended Data Fig. 2e ). rs73397758 ( P = 5.5 × 10 −8 , odds ratio (OR) = 9.16) is ~350 KB (kilobase pairs) downstream of the gene CASC17 , a long non-coding RNA named for a genetic association with prostate cancer 37 , and 570 KB upstream of KCNJ2 , a potassium inwardly rectifying channel 38 . rs143130878 ( P = 1.1 × 10 −7 , OR = 6.87) resides 62,472 base pairs downstream of the gene CCT6B 39 , which is a member of the molecular chaperone (TRiC) family that has been shown to regulate the replication of arenaviruses, including LASV 40 .

A predictor (self-efficacy) exhibited a trend toward significance ( P =.003), playing arguably a similar role as in the original population.

Among children with TD, significantly higher SMF was found in the nonpreferred than in the preferred hand for grip (SFI grip: P = .001) and a trend toward significance using pinch (SFI pinch: P = .007) ( Fig. 2A and B ).

A trend toward significance also appears in the mean Phe/Tyr ratio, with the PKU group having a higher ratio than the MHP group ( p = 0.013).

For example, when BasisVAE was trained using the Phonation data, it was able to detect a trend toward significance between FRS-total severity subgroups and embeddings ( p = 0.02).

In the multivariable analysis, controlling for both female and male age, female age showed a trend toward significance (OR = 1.12, 95% CI: 1.02 - 1.23, p = 0.02), while male age showed no significant effect (OR = 0.99, 95% CI: 0.92 - 1.06, p = 0.75).

ATP2C1 had a trend toward significance ( p = 0.03, OR = 6.76) ( Table 6 ), though after Bonferroni correction only a p ‐value of 0.01 would be considered significant.

Similarly, the association between WMH and global cognition as well as attention remained, while the associations between WMH and executive function or language showed a trend toward significance when adding Aβ-SUVR as a covariate in addition to adjustment for type-2 diabetes-related characteristics and ICV (β = − 0.02, SD = 0.01, p = 0.03 for global cognition, β = − 0.03, SD = 0.01, p = 0.03 for attention, β = − 0.02, SD = 0.01, p = 0.06 for executive functions, and β = − 0.02, SD = 0.01, p = 0.06 for language, Table 4 B).

This was significant for the categories Play ( t (12.54) = 6.37, p < .001) and Distress ( t (11.36) = 20.63, p < .001), with a trend toward significance in the same direction for scratching ( p = .031).

A trend toward significance was detected when dogs receiving ulnectomy, SBRT, and PRT were compared relative to OST ( p = 0.033).

Individual chi-square tests revealed a significant association between active or not active behavior and visitor density level for all three fiddler rays (fiddler 1: χ 2 = 16.392, p < 0.001; fiddler 2: χ 2 = 10.274, p = 0.016; fiddler 3: χ 2 = 27.306, p < 0.001), as well as a trend toward significance for southern stingray 3 (χ 2 = 8.486, p = 0.037) and southern stingray 2 (χ 2 = 7.401, p = 0.060.

Using a vertical brushing method trends toward a negative impact on tooth sensitivity, although this trend is not statistically significant, while the combination method shows a trend toward significance with a p-value of 0.043 (B = -5.249, SE = 2.587, p-value = 0.043, and Exp (B) = 0.005).

A significant interaction for APOE ε4 carriage and time ( P = 0.001) and a trend toward significance for the three‐way interaction (moderate/severe sleep disturbance, P = 0.046, sleep duration category < 6 hours, P = 0.085, and sleep efficiency category 65%–85%, P = 0.070) confirmed modeling stratified for APOE ε4 carriage was warranted.

When analyzing the important predictors in the OS analysis, the Cox regression coefficient showed a trend toward significance for age at diagnosis (HR 2.3, p = 0.05) and less for high or intermediate RS categories (HR 2.54, p = 0.142 and HR 1.35, p = 0.59).

Furthermore, a trend toward significance (p=0.05) was also observed in the type III CZ-Simkova group for GRA6-III-44 vs.

However, it should be mentioned that the p -value showed a trend toward significance, suggesting a possible impact of unsuccessful liberation from VV-ECMO on mortality ( p = 0.05).

Statistical significance and a trend toward significance were declared at P < 0.05 and P < 0.1, respectively.

There was a trend toward significance ( P <0.05) with systolic BP, pulse pressure, and total arterial compliance (Table 3 ).

In terms of knowing about uncontrolled HTN, a higher percentage of participants with HTN (31.70%) were aware of it compared to those without HTN (23.10%), showing a trend toward significance (p = 0.05).

Additionally, most of the detected miRNAs, including the selected miR-150-5p and miR-23b-3p, did not reach the conventional significance threshold of adjusted p -values < 0.05, but they showed a trend toward significance with p < 0.05.

The nested analyses showed a significant difference between baseline and 6 to 18 months post-ART ( P < 0.041), with a trend toward significance between baseline and 1 to 6 months post-ART ( P < 0.051).

Finally, women with alcohol use during pregnancy ( k = 7) did not show a statistically significant difference with those without, although a trend toward significance was detected OR of PPD of 1.88 (95% CI 0.99–3.55, p = 0.051).

The ANOVA indicated a trend toward significance in the interaction between oxygenic level and task condition, F (2, 170) = 3.03, p = 0.051.

In MCI, LME models revealed that cognitive decline was significantly predicted by NfL (β=-0.43, p = 0.006), GFAP (β=-0.38, p = 0.015), and a trend toward significance was observed in Aβ42/40 (β = 0.34, p = 0.051).

At T2, GAF scores of non-users exhibited a trend toward significance, indicating higher values compared to SPICE-users ( F = 4.901, p = 0.051).