Barely Significant
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a trend toward significance

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a trend toward significanceP =0.0631.3× alpha
In the subgroup analysis ( Supplementary Table 2 ), mask contamination showed a trend toward significance with duration of usage for ≤12 months ( P =0.063, R 2 =0.064), while both duration of usage ( P =0.044) and average daily CPAP use ( P =0.021) were significant for masks used >12 months ( R 2 =0.285).
a trend toward significancep = .0631.3× alpha
Positive trials were rated higher than both the neutral and the negative; however, Conover post-hoc tests revealed only a trend toward significance ( p = .063) after Bonferroni and Holm adjustments, despite medium effect sizes for positive-neutral and positive-negative comparisons (r rb = -0.549 and r rb = -0.562, respectively).
a trend toward significancep = 0.0631.3× alpha
First, the ordinal logistic regression analysis restricted to drug-naïve individuals demonstrated that higher baseline Unusual Thought Content severity (OR = 1.79, 95% CI: 1.29–2.50, p = 0.00058) and higher SCoRS scores (OR = 1.33, 95% CI: 1.03–1.70, p = 0.026) remained significantly associated with worse clinical outcomes, while smaller dMMN amplitude showed a trend toward significance (OR = 0.80, 95% CI: 0.64–1.01, p = 0.063).
a trend toward significanceP = 0.0631.3× alpha
There was also a large increase in Blautia seen in the 2’FL intervention; however, due to the high level of heterogeneity seen between individuals, only a trend toward significance was recorded ( P = 0.063) ( Supplemental Table 2 ).
a trend toward significancep = .0631.3× alpha
In a regression analysis, group allocation was the only significant predictor ( p = .007) with depression severity showing a trend toward significance p = .063 (see Table 3 ) with those with higher symptom severity scores showing greater improvement compared with those with lower symptom severity.
a trend toward significancep = 0.0631.3× alpha
Age shows a trend toward significance (B = 0.038, SE = 0.020, 95% CI = [−0.002, 0.077], p = 0.063), while the male gender and income-to-need ratio do not significantly predict tobacco use initiation (B = −0.002, SE = 0.022, 95% CI = [−0.045, 0.042], p = 0.931; B = 0.023, SE = 0.022, 95% CI = [−0.020, 0.067], p = 0.290).
a trend toward significancep = 0.06361.3× alpha
Across-identified profiles, five of the six metrics differed significantly: maximum process length, p < 0.0001, Figure 3 A; total number of intersections, p < 0.0001, Figure 3 B; soma size, p = 0.0001, Figure 3 D; length-to-soma ratio, p < 0.0001, Figure 3 E; and estimated cell territory size, p < 0.0001, Figure 3 F, whereas the terminal-to-primary branch ratio showed only a trend toward significance, p = 0.0636, Figure 3 C.