Barely Significant
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a trend toward significance

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a trend toward significanceP = .0621.2× alpha
Finally, the changes from baseline in commonly used surrogate cardiovascular biomarkers (hsCRP, IL-10, IL-6, TNF-α, and fibrinogen) between the FTC/TDF and 3TC/ABC arm in a subset of 159 subjects were not significant except a trend toward significance with fibrinogen ( P = .062) (Table 5 ), perhaps with a larger sample size it may have achieved significance.
a trend toward significancep = 0.06251.3× alpha
These results indicate that the miRNA combinations show markedly stronger predictive performance in patients within the extreme (average AUC ~ 0.8) CAPRA risk category compared to the moderate group (average AUC ~ 0.54), with a statistically significant difference by paired t ‐test ( p < 0.001) and a trend toward significance by non‐parametric testing ( p = 0.0625, Wilcoxon) (Figure 6C ).
a trend toward significancep = .0631.3× alpha
Positive trials were rated higher than both the neutral and the negative; however, Conover post-hoc tests revealed only a trend toward significance ( p = .063) after Bonferroni and Holm adjustments, despite medium effect sizes for positive-neutral and positive-negative comparisons (r rb = -0.549 and r rb = -0.562, respectively).