Barely Significant
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a trend toward significance

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a trend toward significancep = 0.0761.5× alpha
Patients who completed treatment with lurasidone had numerically larger decreases in BPRSd scores than the overall LOCF analysis sample; however, there were no significant differences from placebo for either dose group for completers at day 42, perhaps as a result of small sample size. For the PANSS total score (secondary efficacy measure), the LS mean change from baseline to week 6 (LOCF) was significantly greater in the lurasidone 120 mg/day group compared with placebo ( p = 0.009), and a trend toward significance was noted for the lurasidone 40 mg/day group ( p = 0.076) (Table 2 ).
a trend toward significanceP =0.0761.5× alpha
Interestingly, when examining the rate of referrals to electrophysiology by race in the No BPA group, Black patients exhibited a trend toward less referrals (HR, 0.73 [95% CI, 0.49–1.09]; P =0.13; Figure 3A ), but this trend was reversed in the BPA group (HR, 1.15 [95% CI, 0.85–1.57]; P =0.34; Figure 3B ), with a trend toward significance for the interaction between race and BPA ( P =0.076).
a trend toward significancep = 0.0761.5× alpha
A Welch’s two-sample t test of PC1 scores revealed that AHR activation showed a trend toward significance ( t = 2.68, p = 0.076), whereas no meaningful effects were observed for other pathways: AR (t = 0.48, p = 0.68), ER ( t = − 0.93, p = 0.43), and SP1 ( t = 0.37, p = 0.74) (Supplementary Fig. 4c ).
a trend toward significancep = 0.0761.5× alpha
A statistically significant inverse correlation was found between the FC at FU1 and change in GC at FU2 ( r = −0.771, p = 0.003), but only a trend toward significance was noted between the two deltas at FU1 ( r = −0.530, p = 0.076, see Figure 7 ).
a trend toward significanceP = 0.0771.5× alpha
Again, when all birds were considered individually, neither hemisphere showed a significant correlation between the quality of song imitation as measured by SI and new neuron density in NCM, although there was a trend toward significance in the left hemisphere only (n = 21; left: r 2 = 0.155, P = 0.077; right: r 2 = 0.055, P = 0.305).