“an increasing trend”

Results Our results showed an increasing trend in total medical cost (from 2,383 to 2,780 USD, p = 0.032) and diabetes related cost (from 1,655 to 1,857 USD) for those diabetic patients during the study period.

For types 1 and 3, a declining trend was observed with increasing age while type 2 demonstrated an increasing trend with age which achieved level of significance ( p = 0.032) between younger and older cohorts.

With the extension of treatment time, it showed a decreasing trend at 25 and 34 °C (Tukey’s test: 25 °C: F 2, 6 = 28.36, p = 0.001; 34 °C: F 2, 6 = 126.60, p < 0.001; Supplemental Table S1 ), a “first decreasing and then increasing” trend at 28 °C (Tukey’s test: F 2, 6 = 8.49, p = 0.018, Supplemental Table S1 ), and an increasing trend at 31 °C (Tukey’s test: F 2, 6 = 6.49, p = 0.032, Supplemental Table S1 ).

The reports suggested a decrease in the number of tuberculosis cases in children under five since 2000.This decline was markedly interrupted in 2020, after which an increasing trend in the incidence of cases within this age group was observed (APC = 26.64; p-value = 0.032).

The average incidence of work-related mental and behavioral disorders was 35.48 per 100,000 RGPS links during the period 2003-2019, with an increasing trend (APC = 9.67%; p = 0.033) for Brazil.

There was an increasing trend for stage I diagnoses in the region of Campinas ( p = 0.033).

post: 0.963 ± 1.736, p = 0.125, Cohen's d = −0.442, adjusted 95% CI of difference: −2.225 to 0.230) but an increasing trend could be found in IPL (pre: 0.814 ± 1.336 vs. post: 1.789 ± 1.167, p = 0.033, Cohen's d = −0.589, adjusted 95% CI of difference: −1.875 to −0.074).

The annual overall crude incidence was 5·83 per 100 000 inhabitants, with an increasing trend ( P = 0·033).

When analyzing the approved values, there was an increasing trend in the previous period ( p = 0.033), soon after there was no significant change ( p = 0.254) and no significant change in the pattern in the later period ( p = 0.155), although apparently there is a breakpoint on the day of the disaster, which is not significant (Fig. 4 ).

There was an increasing trend in the proportion of male patients over years (R 2 = 0.448, p = 0.034), while the average age showed a modest decline, which however, was not statistically significant (R 2 = 0.158, p = 0.256; Fig. 2 ).

The evidence for an increasing trend in point estimate was weaker after the association is fully adjusted for other diabetes risk factors (OR linear effect 1.10, 95% CI 1.01 to 1.19, p=0.034).

In addition, for the proportion of apoptotic cells in the total PBMCs, the HIGH group showed a decreasing trend, while the LOW group showed an increasing trend, resulting in a significant difference in the change ( p = 0.034; Figure 2 ). 3.4.

Therefore, we performed further analysis and found that after postoperative day 107, the risk of cumulative ischemic events showed an increasing trend according to the number of CYP2C19 LOF alleles (hazard ratio, 6.176; 95% CI of ratio, 1.145 to 33.32; P = 0.0342; Fig. 1D ).

Among the new cases of leprosy detected, the proportion of MB cases was relatively high throughout the 15-year period investigated, with an increasing trend from 62% in 2000 to 87% in 2014 (P = 0.035).

In addition, Lin et al ., observed that, among maintenance hemodialysis patients, the GSTM 1 null genotype was associated with a significantly lower antioxidant capacity than the GSTM+ genotype.[ 20 ] The null/low polymorphisms of the GSTM 1 and GSTT 1 genes have been associated with the risk of developing ESRD in North Indian patients.[ 17 ] In addition, Singh et al ., reported that patients with transplant therapy demonstrated an increasing trend toward carrying the GSTM 1 null genotype (51.3%) versus healthy controls (40.4%) with a risk of about 1.5-fold ( P = 0.035), and patients with a variant genotype of GSTM 1 were at the higher risk of transplant rejection.[ 21 ] The frequencies of important functional mutations and alleles result in broad ethnic variation.

Following an increasing trend of cirrhosis-related mortality before the pandemic, with a semiannual percentage change (SAPC) of 0.54% [95% confidence interval (CI): (0.0–1.0%), p =0.036], a precipitous increase with seasonal variation occurred during the pandemic (SAPC 5.35, 95% CI: 1.9–8.9, p =0.005).

Secondary analyses An increasing trend of postpartum suicide attempt was indicated among adolescent fathers (aged 11–19 years) (IRR 1.06 (1.00–1.11), P = 0.037), but the association is no longer significant after adjusting for multiple comparison (adjusted P = 0.096).

1 a, prior HBV screening showed an increasing trend across years of migration, from 14.0% between the years 2000–2005, to 27.0% in years 2021–2023 ( p = 0.037).

The unit cost of high-risk population intervention showed a declining trend over the years (r=−0.791, p=0.034) (see online supplementary appendix C), while the unit cost of public awareness showed an increasing trend over the years (r=0.785, p=0.037) (see online supplementary appendix D).

There was an increasing trend in patients with large ocular deviation (≥30 prism diopters) over time among patients with AACE who underwent surgical treatment ( P = .037).

Among all microvascular complications, there was an increasing trend in the proportions developing impaired eGFR (3.6 vs. 3.9 vs. 6.6%, trend P = 0.037) and ESRD (0 vs. 1.5 vs. 2.3%, trend P = 0.036) among those with 0, 1, or 2 copies of the HP 2 allele, respectively.

Among all clusters, cluster 12 exhibited an increasing trend in proportion in SCZ, from 8.48% in the HC to 13.27% in NRES and 20.16% in RES ( P = 0.037 for SCZ and HC, P = 0.003 for NRES and RES, Fig. 1F ).

aeruginosa showed an increasing trend over time ( Rs=0.738, P=0.037 ).

Despite representing only a small proportion of the total diagnoses, an increasing trend was observed each year ( P = 0.038).

Cytoplasmic PANK4 levels showed an increasing trend in aged WT mice [One-way ANOVA: F (2, 13) = 4.242, p = 0.0382; Figures 2D,G ], with significant reduction in Pank4-CKO versus 18M+WT ( p = 0.0488).