“an increasing trend”

The Spearman’s correlation test for association between annual PTH rates and time (year) performed for the adult age group showed a statistically significant, mild to strongly positive correlation, indicating an increasing trend of adult PTH rates over time (year) (Rs = 0.64 [95% CI: 0.28 to 0.84], P = 0.003).

Dopamine and norepinephrine were associated with an increasing trend in serum K + concentrations (β = 0.584; SE = 0.196; p = 0.003 and β = 0.811; SE = 0.251; p = 0.001, respectively).

However, the proportion of MDSCs among total urinary cells significantly decreased in the non-recurrence group, whereas it did not decrease in the recurrence group and instead showed an increasing trend ( p = 0.003) (Fig. 3 ).

By using stage 1 as a reference, an increasing trend in all-cause mortality is shown in patients with higher stages (stage 2: aHR 1.55, 95% CI 1.17–2.07, P = 0.003; stages 3–4: aHR 2.69, 95% CI 1.92–3.76, P < 0.001), as well as for cardiovascular mortality during a follow-up of 50,895.4 person-years.

In the 15–64 age group, ankle fracture surgery decreased from 8,168 in 2008 to 6,281 in 2022 ( p = 0.004), while in the 65 + age group, there was an increasing trend in ankle fracture surgeries from 2,509 in 2008 to 3,276 in 2022 ( p = 0.003).

Before intervention, the positive density of MDRO in the orthopedic ward showed an increasing trend (β 1 = 0.02, P = 0.003).

Over this period, the age-standardized prevalence rates of stroke exhibited an increasing trend: 1450.8, 1935.9, 2337.4, 2667.3, and 3024.5 per 100,000 ( p = 0.003).

Wear score showed an increasing trend from T 0 to T 1 ( P = 0.003, P = 0.004), and no difference was found between T 1 to T 2 .

Patients without diabetes showed an increasing trend with age in plaque rupture ( P =0.004) and lipid‐rich plaque ( P =0.018), whereas patients with diabetes had a high prevalence of these vulnerable features at an early age that remained high across age groups.

ALFF of right BA39 was positively correlated with age and showed an increasing trend in deaf group with age ( r = 0.574, p = 0.004).

The results of the presented study obtained on skeletal muscle showed an increasing trend of Caspase 9 immunoreactivity from 4 up to 8 h after death ( p = 0.004), followed by stable—though slightly decreased—levels up to 24 h; a significant immunoreactivity decrease was observed 72 h after death.

Segmented regression showed an increasing trend in impact factor for publications during 1972 to 1996 ( β = 0.16, p = 0.004) and a decreasing trend during 1997 to 2023 ( β = −0.048, p = 0.005).

Similarly, overall internal fit showed an increasing trend as pixel offset values increased ( p = 0.004).

However, at the 15 mm section, an increasing trend in LWT from P1 to M2 was evident, with significant differences between molar and premolar regions ( P = 0.004).

The linear-by-linear association test revealed that except rs3104746 ( P = 0.638), the risk allele G of both rs9933638 and rs12443621 showed an increasing trend from light smoking to heavy smoking groups ( P = 0.004 and P < 0.001, respectively, p trend < 0.001, Table 4 ).

Sodium showed an increasing trend in group 1 at T2 (p = 0.004), T3 (p = 0.002), and T4 (p = 0.011), which was statistically significant.

58%, p < 0.001), along with an increasing trend in the proportion of endoscopic therapy (G1-4 groups, 14.9% vs. 25.4% vs. 24.6% vs. 30.9%, p = 0.004).

The positive effect of time showed an increasing trend of SBP (p=0.004) during time.

SPD serum levels were significantly higher in ACPA-positive subjects compared with healthy controls (158.5 ± 132.3 ng/mL vs 61.27 ± 34.11 ng/mL; p < 0.0001) and showed an increasing trend from ND subjects to LSRD patients ( p = 0.004).

In the Cochran–Armitage test, an increasing trend was observed in the infection rate among close contacts ( P = 0.004).

There was an increasing trend for the Lawani index of authors, AAGR = 9.4%, p = .004, as of affiliations, AAGR = 11.2%, p = .002 and of countries, AAGR = 6.8%, p = .002.

During the period from 2014 to 2021, the number of hospitalized cases of CD had an increasing trend year by year ( r = 0.876, p = 0.004); meanwhile, there was no significant change in the number of UC inpatients ( r = −0.119, p = 0.780) ( Figure 1 ).

RCS results demonstrated a nonlinear dose-response relationship between OSA risk and FI levels, with an increasing trend (P = 0.004).

Six months after surgery, BOP had a decreasing trend in the PRF and CGF groups ( P = 0.003 and P = 0.043), with an increasing trend in the control group ( P = 0.004) ( Table 3 ).

In Figure 8 , it is observed that over time the values show an increasing trend, a trend that, from a statistical point of view, has a significant effect ( p = 0.004, η 2 p = 0.235).