Secondary analyses An increasing trend of postpartum suicide attempt was indicated among adolescent fathers (aged 11–19 years) (IRR 1.06 (1.00–1.11), P = 0.037), but the association is no longer significant after adjusting for multiple comparison (adjusted P = 0.096).
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There was an increasing trend in patients with large ocular deviation (≥30 prism diopters) over time among patients with AACE who underwent surgical treatment ( P = .037).
Among all clusters, cluster 12 exhibited an increasing trend in proportion in SCZ, from 8.48% in the HC to 13.27% in NRES and 20.16% in RES ( P = 0.037 for SCZ and HC, P = 0.003 for NRES and RES, Fig. 1F ).
aeruginosa showed an increasing trend over time ( Rs=0.738, P=0.037 ).
The unit cost of high-risk population intervention showed a declining trend over the years (r=−0.791, p=0.034) (see online supplementary appendix C), while the unit cost of public awareness showed an increasing trend over the years (r=0.785, p=0.037) (see online supplementary appendix D).
Among all microvascular complications, there was an increasing trend in the proportions developing impaired eGFR (3.6 vs. 3.9 vs. 6.6%, trend P = 0.037) and ESRD (0 vs. 1.5 vs. 2.3%, trend P = 0.036) among those with 0, 1, or 2 copies of the HP 2 allele, respectively.
1 a, prior HBV screening showed an increasing trend across years of migration, from 14.0% between the years 2000–2005, to 27.0% in years 2021–2023 ( p = 0.037).
Despite representing only a small proportion of the total diagnoses, an increasing trend was observed each year ( P = 0.038).
Cytoplasmic PANK4 levels showed an increasing trend in aged WT mice [One-way ANOVA: F (2, 13) = 4.242, p = 0.0382; Figures 2D,G ], with significant reduction in Pank4-CKO versus 18M+WT ( p = 0.0488).
During the study period, there was an increasing trend toward using MCS (Cohran Armitage P = 0.039).
Pre-pregnancy body mass index of reproductive-age women shifted from an increasing trend in the pre-epidemic period to a declining trend in the post-pandemic period (β=-0.05, 95%CI: -0.10 to -0.01, P = 0.039), in line with the accelerated decline of birth weight nine months later.
Specifically, we observed an increasing trend in risk of migraine as COVID-19 genetically increased (β = 0.298, 95% confidence interval [CI]: 1.015-1.790, p = 0.039), and the data were robust without obvious bias.
Using the RoB-2 tool, only 22 (23.9%) published trials had a low risk of bias (Figure S3), with an increasing trend over time (OR: 1.09; P = 0.039).
Unlike the Ccl2 levels, the CCL2 concentrations in the uterus did not change between gestational days (figure 4D ); however, they displayed an increasing trend from GD20 to 22 in the fetal membranes (figure 4E ) and from GD17 to 22 in placenta ( p =0.040, figure 4F ).
However, the frequency of NPBs shows an increasing trend with increasing GS ( p = 0.04; p trend = 0.01; Figure 2 B).
Fluconazole-non-susceptible Candida isolates showed an increasing trend from 2021 ( p = 0.040), attributed to increases in C. glabrata and C. krusei BSIs ( Figure 1 and Supplementary Figure S1 ).
Three studies assessed changes in femoral neck BMD, and the random-effects model showed an increasing trend (SMD = 0.24, 95% CI: −0.01–0.49), but this did not reach statistical significance, with moderate heterogeneity (I 2 = 70%, p = 0.04).
By day 28, while the duodenum showed a non-significant decreasing trend in Vh and an increasing trend in Cd with increasing DDGS, the most pronounced change was in the Vh to Cd ratio, particularly at 20% inclusion, showing significant linear effects ( P = 0.040).
The number of scholarly activities per resident also showed an increasing trend over time ( P = .04).
As shown in Figures 5A – C , the mean dwell time in state 5 was significantly lower for HF patients compared with HCs (Mann–Whitney U-tests, z = −2.63, p = 0.009 × 5 < 0.05 after Bonferroni correction), although in state 2, the HF patients showed an increasing trend in mean dwell time (Mann–Whitney U-tests, z = −2.056, p = 0.04 × 5 > 0.05 after Bonferroni correction).
Our time-series analysis documented an increasing trend in the monthly rates of HIV tests per 1000 patient-visits before the policy change (average monthly increase of 0.19 [CI, 0.01–0.38], p = 0.04) ( Figure 1A ).
An increasing trend in mortality HRs was observed with decreasing CD4% in the crude analysis, and adjusted for age, sex, and PVL ( p = 0.04).
Among individuals under 19 years of age, an increasing trend in SLE prevalence was observed between 2010 and 2015 (APC=22.9%; p=0.0400), sustained from 2015 onwards.
However, for Hispanic or Latino patients, there was an immediate decrease in volume levels after the shutdown to approximately three quarters of its preshutdown level and an increasing trend over time after shutdown ( p =0.04 and 0.006, respectively) ( Figures 2 and 3 and Table 2 ).
There was an increasing trend in the percentage of infants receiving multiple PND courses from 25% in 2010 to 34% in 2020 (p=0.04).