“an increasing trend”

A more recent cross‐sectional study conducted between 2020 and 2024 reported an increasing trend of antibiotic‐resistant CE over time.

At all timepoints, relative to contralateral control, central nuclei were elevated in the MTJ near the intramuscular tendon with an increasing trend over time (Fig. 3 e, S3 ).

Notably, the temporal evolution of keywords demonstrates an increasing trend towards tumor microenvironment modulation, biomarker-driven patient stratification, metabolic reprogramming, and combination immunotherapeutic modalities.

An EAPC greater than 0 indicates an increasing trend in ASR over time, whereas an EAPC less than 0 signifies a decreasing trend.

Although ACDF reduces opioid dependence for most patients, there is an increasing trend for opioid prescriptions in patients with cervical pain ( 3 , 5 , 6 ).

Abstract Environmental contamination has shown an increasing trend due to urbanization, industrialization, and the intensive use of pesticides and fertilizers in Ethiopia.

In another study using coextruded FePP, CA, and TSC with an iron concentration of 80 mg Fe/kg rice, an increasing trend in iron solubility was observed with higher molar ratios of CA and TSC, and iron absorption from the coextruded meal with a molar ratio of 1:0.1:2.1 was equivalent to that from the FeSO 4 reference meal [ 9 ].

The production rate of isoprenol showed an increasing trend until day 3 of fermentation, but slowed down as the concentration in the aqueous phase surpassed 3 g/L, a concentration previously shown to inhibit E. coli replication.

Subsequently, the fluorescence intensity ratio ( I A / I B ) for the A and B bands was calculated based on the fluorescence profile in acetonitrile, showing an increasing trend from QL-CHO to N-COOMe ( Fig. 3e ).

While the frequency of stings has exhibited an increasing trend, the severity of symptoms experienced by individuals appears to correlate with the degree of RIFA infestation.

The primary surgical approaches for stage 4 ROP include scleral buckling (SB), lens-sparing vitrectomy (LSV), and lensectomy with vitrectomy (L + V), with the choice depending on disease progression and other anatomical factors.[ 4 , 5 ] SB, which involves either segmental or encircling techniques, relieves traction by creating an indentation of the sclera, thereby promoting reattachment and stabilizing the retina.[ 6 , 7 ] While there is an increasing trend toward vitrectomy for ROP management, previous literature has established the indications for LSV in Stage 4A/4B ROP.[ 8 , 9 , 10 , 11 , 12 , 13 ] However, there are limited case series and a scarcity of longer-term follow-up studies on the specific role of SB in the management of stage 4 ROP.[ 14 , 15 ] Moreover, lacunae exist in the management of Stage 4B ROP with segmental or encircling buckles.[ 7 , 16 , 17 ] Our study describes the overall role of segmental/encircling bands in management of stage 4A/4B ROP in large case series with longer follow-up.

When disease control remains inadequate, there is an increasing trend toward the use of biologic agents such as adalimumab and tofacitinib.

Our results show that consistently long sleep, particularly with an increasing trend, is significantly associated with accelerated cognitive decline.

Our findings suggest a decreasing trend in recorded CKD rates and an increasing trend in recorded hemodialysis rates within the healthcare system.

Conversely, Isfahan, Chaharmahal and Bakhtiari, and Sistan and Baluchistan were the only provinces with an increasing trend, a finding underscored by their FOI being higher than their ICR.

In contrast, ACC/AHA-defined hypertension showed an increasing trend (AAPC 1.92%; 95% CI: 0.35 to 3.52), as did the reclassified group (AAPC 2.88%; 95% CI: 1.31 to 4.48) ( Supplementary Table S5 ).

It could be seen that at both time points, the expression levels of COL2A1 in the blank group, NCCL-CG group, FCCL-DG group, and WCCL-DG group showed an increasing trend, and the WCCL-DG group was closest to the Sham group (Fig. 8a,b ).

The Loess Plateau exhibited a significant decreasing trend in March EGR from 2000 to 2023, whereas the Mongolian Gobi showed no such decline and instead exhibited an increasing trend (Fig. 3 ).

It can be found that the initial stress, residual stress, the time duration required for stress relaxation to reach stability and the stress relaxation magnitude of the sample after acid etching generally show an increasing trend with the increase of the strain level.

in the environment, despite an increasing trend having been well-evidenced in human medicine 37 , 40 .

WHO estimates reveal an increasing trend in the prevalence of anemia (21.70% in 2019 vs 23.30% in 2022), which could also be observed in this study. 10 In the age group between 18-49 years, anemia was more frequent in females than in male patients, while in the older age groups, anemia prevalence was higher in males compared to females.

Previously, we showed an increasing trend in hepatic NEFA levels after CR in OLETF (Cornejo et al., 2020 ) and in total FAs (Figure 5a ).

Surface DOC, which comprises <1% of total SOC, showed an increasing trend associated with warming-enhanced plant inputs, yet this small increase was insufficient to counterbalance the substantial POC loss.

S14 illustrates the changes in modulus, revealing an increasing trend with lower PEG content.

Specifically, CAF treatment led to a reduction in G-lignin and an increase in S-lignin subunits, resulting in an increasing trend of S/G ratio ( Figs. 6c and S9b ).