“an overall trend”

There was an overall trend of improvement in most of the tests, except for the lesion volume on MRI, which increased significantly.

There was an overall trend for higher response rates (complete plus partial responses) in high KRAS4A and KRAS4B cmRNA expression groups.

Conclusion Our results show an overall trend of significantly increasing loneliness among adolescents over a 24-year period, particularly among 16–19-year-old girls.

The number of diseases presented an overall trend of mild decrease with the time of TPA per week increasing within a certain range in 2015 (Fig. 1 A).

We observed an overall trend wherein occlusion of the RBS was associated with a higher value of ES CcdB .

While we saw an overall trend of higher PRNT50 titer in the IN + IN and IM + IN, the differences between vaccination routes were not statistically significant (Fig. 3 e).

Figure 1 illustrates that HB exhibited an overall trend of stabilization (AAPC = 0.44, 95%CI: -0.94-1.84) but we observed a rise during 2004-2007 (APC = 9.13, 95%CI: 2.02-16.74), a decline during 2007-2014 (APC = -3.53, 95%CI: 2.02-16.74), and a steady level during 2014-2022 (APC = 0.86, 95%CI: -0.61-2.35) (Figure 1A ).

Therefore, the interpretation of an overall trend must be done with caution.

db/db mice with PAX6 replenishment displayed a long‐term improvement in hyperglycemia and elevated serum insulin level with an overall trend up to 5 months compared to db/db mice receiving AAV‐Ctrl (Fig 4A and B ).

An overall trend for these patients showed an initial increase in aggregate kidney volumes with a peak volume of 410 cm 3 ( Fig 2 ).

For an overall trend, we observed that student satisfaction with each of the domains featured in the ISA 2 were higher as compared to levels of satisfaction of those same domains as captured in the ISA.

Lp(a) and aortic valve stenosis Despite the considerable heterogeneity in the design and findings of included studies, an overall trend toward increased risk of calcific AVS was observed for higher-Lp(a) groups.

Conclusion and implication From the perspective of an overall trend, our study reveals, for the first time, that Hg concentrations in fish decreased over time in China over the past three decades and exhibited a sharp contrasting trend to the increasing Hg emissions.

Second, while depression and loneliness scores were higher for LGB participants than heterosexual participants, there was an overall trend of worsening mental health, regardless of sexual orientation.

That is, for cement concrete, the compressive strength shows an overall trend of “first increasing and then decreasing” during the process of temperature differential cycling.

It showed an overall trend of initial decrease followed by an increase.

There was an overall trend for this model, with an interaction between ELS and ketamine treatment as the strongest predictor of ameliorated female behavior ( Fig. 3 K ).

The results indicated an overall trend of elevated expression of RAP2C-AS1 and LINC01711 in BLCA cells compared to that in SV-HUC-1 cells (Fig. 13 c,d), which corresponded to our previous analysis based on the public database.

As the treatment time and the voltage increased, the fatty acid content in the maize showed an overall trend of increasing, with a significant increase especially under the treatment condition at 50 KV for 120 s.

Conclusion This study showed an overall trend towards the increased pharmacological treatment of FM in South Korea.

Typically, this leads to an overall trend of increasing potency from the earliest to the most recent compounds.

However, the Japanese government stopped subsidizing high-cost care, such as nursing homes, after the revisions of the LTCI ( 27 ), which promoted an overall trend of shifting from institutional care to domiciliary care.

LEV and MER showed an overall trend of increasing susceptibility for ACB, with slightly lower activity in 2020–2021.

We observed an overall trend for lower seropositivity in gestating females (8.4%, 29/344) versus non-gestating females (11.3%, 276/2450) ( Figure 6 a, Supplementary Table S4 ,) but the difference was not significant.

The serial echocardiographic evaluations conducted in patients without preexisting structural heart disease demonstrate an overall trend towards an improved cardiac function and a reduced myocardial thickening at 1-year follow-up.