Barely Significant
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an overall trend

3,009 sentences · 3,009 papers · 33,194 search hits before verification · confirmed specimen

Sighted at

p=0.2

Listed by Hankins (2013) · Otte et al. (2022)

In the literature

Nonetheless, this study revealed an overall trend of increasing healthcare costs, and given the increasing number of patients with HF, as well as the introduction of new therapeutic agents, invasive and non-invasive treatments, such as device-based therapies, and the increasing adoption of various healthcare services, such as education and remote management of HF, we expect the healthcare cost for HF to continue to rise rapidly in Korea.
Although we did not observe a significant difference between doses, there was an overall trend of down regulation of both Phosphor‐RB and Cyclin D1 across cell lines suggesting an initiation of senescence phenotype while inhibiting cell proliferation (Figure 2B ). 3.3 DFMO inhibits neurosphere formation and progression in neuroblastoma cell lines We investigated the effect of DFMO on sphere initiation, formation, and development in different cell lines.
DFMO inhibition of neuroblastoma tumorigenesis.
Cancer Med · 2024 · PMC11058673
hepaticus , these T cell-specific transcription-factor-deficient mice developed colitis with varying degrees of pathology, with an overall trend of double-deficient Prdm1 fl/fl Maf fl/fl Cd4 Cre mice developing the most severe disease, and the Prdm1 fl/fl Cd4 Cre and Maf fl/fl Cd4 Cre mice each developing mild to moderate colitis, respectively compared to Prdm1 fl/fl Maf fl/fl control mice (hereafter referred to as control mice), which showed no inflammation or colitis (Fig. 1a–c and Methods ).
Individual insect species are typically only present as flight-capable adults for part of each annual cycle, so composition and numbers will vary as the season progresses, with populations of different species increasing and decreasing asynchronously—although with an overall trend of increase in spring, decrease in autumn, and a winter minimum.
Monitoring insect numbers and biodiversity with a vertical-beam entomological radar.
Philos Trans R Soc Lond B Biol Sci · 2024 · PMC11070261
We found an overall trend that tyrosine plasma levels increased after the intake of the synbiotic supplement and that this relationship again depended on the baseline homeostatic balance of the gut microbiome (i.e. the F/B ratio; β Group = 0.09, SE = 0.20, P = 0.642; β F/B ratio = 0.60, SE = 0.34, P = 0.086; and β GroupxF/B ratio = −0.81, SE = 0.36, P = 0.026; see Table S6 ).