Barely Significant
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borderline significance

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The DD genotype alone, reaching borderline significance in the univariate analysis (42% in cases vs 31% in controls; p = 0.056) remained significant also after adjustment for conventional risk factors (p = 0.005) with a independent role on predicting events (OR 2.39 CI 1.25–4.58, p = 0.008); whereas the CYP11B2 polymorphism (CC genotype, 27% vs 17%, p = 0.054) reached borderline significance only in the crude analysis, but lost an independent role after adjustment for confounders.
borderline significanceP = 0.0561.1× alpha
The model with the best fit was the one in which, with adjustment for age and MELD, “high” (≥31.7 kPa) SS was associated with 2.70-fold higher risk of event occurrence, with borderline significance ( P = 0.056) ( Table 3 , Model 4 for SS).
borderline significancep = 0.0561.1× alpha
KPS (HR = 0.932, CI [0.884; 0.990], p = 0.020) and bone metastases as the SBRT treating site (HR = 0.225, CI [0.065; 0.775], p = 0.018; Figure 3C ) appeared to be significant favorable prognostic factors in univariate analysis ( Table 4 ), with the overall number of one metastasis at borderline significance level (HR = 0.371, CI [0.134; 1.025], p = 0.056).