12 and its extension study 13 only showed a statistically borderline significance ( p = 0.0596) for a reduced hazard ratio (HR) for the time to the first relapse and demonstrated nonsignificant improvements in a number of secondary end points in patients treated with TCZ.
Despite borderline significance ( p = 0.06), needle length was retained in the final model, suggesting plausibility as a risk factor independent of pleura-to-lesion distance.
In 12,654 patients from seven studies where multiple anticancer agents were used in the procedures, TACE was associated with a 25% reduction in hazard of death (HR = 0.75, 95% CI = 0.64–0.88, p = 0.0004), while in 436 patients from three studies that only used one anticancer agent, the reduction associated with TACE was smaller and of only borderline significance (HR = 0.83, 97% CI = 0.68–1.01, p = 0.06) but showed higher homogeneity ( I 2 = 0, p for heterogeneity = 0.66).
Meta-regression of antidepressant effects in the main analysis Baseline depressive symptoms had borderline significance as moderators of the antidepressant effects of exercise (B = 0.156, 95%CI 0.008-0.3223, p = 0.06, R 2 = 0.09).
Clinical results Regarding DFS, six out of seven studies reported a significant statistical benefit of perioperative RT, whereas one study reported borderline significance ( P =0.06); regarding OS, four out of six studies reported a significant statistical benefit whereas one study reported borderline significance ( P =0.053) and one study showed nonsignificance ( P =0.480) 22 .
The observed significant independent associations were unchanged with further adjustment for current BMI at 3 months postpartum with the exception of that for adiponectin, which was attenuated to borderline significance ( P =0.06) (Table 4 ).
Borderline significance was seen for: multiple meningiomas ( p = 0.060, 63% vs 32%), obesity with BMI >30 ( p = 0.061, 22% vs 44%), and imaging defined brain invasion ( p = 0.063, 50% vs 28%).
Notably, the IMRT arm showed higher local control, despite having a larger clinical target volume (i.e., the target volume of which is planned to receive the prescribed dose with borderline significance, mean 439 vs. 294 cc, p = 0.06) ( Supplementary Table S2 ).
The CRP had borderline significance for prediction of serum OGL results ( p = 0.060).
Diabetes was associated with significant mortality risk (HR: 2.65 CI95%: 1.20 - 5.85; p = 0.02), while diabesity showed borderline significance (p = 0.06).
COMT 24938A/G was associated with waist circumference at S-46 with borderline significance, where an increment of five cm in waist circumference increased the odds for the GG-genotype by 4% (OR = 1.04, CI = 1.00–1.09, p = 0.06).
Fourth, publication bias assessment showed borderline significance (Egger’s P-value= 0.060), suggesting possible selective reporting of positive results.
While the association reached statistical significance in the paternal and combined models, the maternal-only model also showed a directionally consistent effect, but with borderline significance ( P = 0.06).
The KDM sub-population also exhibited a two-fold increased risk of having ‘general depression’ although this difference held a borderline significance ( p = 0.06).
Similarly, the borderline significance of tumor thickness in the multivariable model ( p = 0.060) likely reflects insufficient statistical power due to the small sample size rather than a true absence of effect.
Adjusting for O 3 , PM 2.5 , or CO resulted in only minor decreases in effect estimates for PM 2.5–10 , with borderline significance (corresponding p -values = 0.06, 0.10, and 0.05, respectively).
Carriers of the rs4149601 GG-genotype together with the rs2288774 CC-or CT-genotype, as compared to non-carriers of this combination, displayed significantly lower P-renin and borderline significance for systolic salt sensitivity (P = 0.06–0.08) whereas there was no significance in diastolic salt sensitivity and Nt-proANP ( Table 3 ).
Sensitivity analysis excluding this study reduced heterogeneity ( I 2 =6%) while increasing the overall strength of the results to borderline significance (MD, −26.53; 95%CI, −53.72 to 0.66; P = 0.06).
Moreover, fever (64.3% vs 19.6%, p < 0.0001) and cough (42.9% vs 15.0%, p = 0.0003) were significantly more frequent in false than true negatives, while chronic obstructive pulmonary disease was more frequent in true than false negatives, with a borderline significance (16.5% vs 4.8%, p = 0.06).
80%, p = 0.05) and previous HPE had borderline significance (100% vs. 83%, p = 0.06)—Table 3 .
observed a drop to borderline significance (p = 0.06) for number of recurrence lesions when adjusted for disease-free interval, number of recurrence lesions at imaging and complete cytoreduction after SCS ( Salani et al., 2007 ).
In contrast, at a concentration of 5 μg/ml, viability revealed a significant difference compared to healthy controls ( P < 0.05), while showing borderline significance ( P < 0.06) compared to the 2.5 μg/ml concentration. 2.5 μg/ml concentration showed a high percentage of viable cells, without showing a significant difference with controls.
Fresh weight of Okra showed borderline significance ( p ~ 0.06) when compared with control group.
In addition, the association reported at borderline significance between genetically predicted HDL-C and MDD in the univariable MR model (OR ivw =0.97, 95% CI = 0.95–1.001, p = 0.06) was enhanced in the MVMR model (OR = 0.98, 95% CI = 0.95–0.998, p = 0.03).In contrast, the connotations between genetically expected TC, LDL-C and MDD, the relations between genetically anticipated TG, LDL-C and AD, and the association among genetically expected LDL-C and AD observed in the univariable MR model were diminished and no longer significant in the MVMR model.
Stage 1 Significant associations ( P < 0.05) with the DIVA-5-ID were found for questions 1, 2, 3 and 6, and borderline significance ( P = 0.06) for question 8 ( Table 3 ).