Although the Aclame collection contains over 122,000 proteins from 2300 mobile genetic elements, we found only a very limited number of proteins with highly significant ( E = 0.01) and borderline significant ( E = 1) similarity to primases.
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Gene expression LAN and EVR treated rats showed a significant lower gene expression of SSTR2 while expression of SSTR5 was increased (borderline significant) in the LAN treated rats (Figure 5 ).
The false discovery rate (FDR)-corrected effect of ampicillin was only borderline significant and was limited to a few innate immune-related cytokines and chemokines: interleukin-1β (IL-1β), macrophage inflammatory protein-1α (MIP-1α), and interferon-γ (IFN-γ) ( Figure 7 A,B).
The frequencies of TNF-α- or IFN-γ-secreting CD4+ and CD8+ T cells in the NVX-CoV2373 group were not significantly increased, whereas there was a borderline significant increase in the frequencies of TNF-α- or IFN-γ-secreting CD4+ and CD8+ T cells in the mRNA vaccination group.
Using χ 2 for categorical variables, significant differences were found in %BF measured by the DDM and BMI for both boys and girls, and borderline significant differences in silhouettes chosen for ideal weight status for both genders.
Active MMP-2 also correlated with proMMP-9 (r = 0.6, p = 0.005), as well as active MMP-9 (r = 0.45, p = 0.047), but the later was borderline significant.
[ 47 ], conducted on Italian patients with clinically localized prostate adenocarcinoma, indicated a borderline significant association between UPFs consumption and higher odds of PC in the energy-adjusted model, though association was no longer significant after adjustment for other confounders such as age, BMI, education, smoking status, and physical activity.
The control showed higher VA than 50 keV, but the effect size was small and the p-value borderline significant, and the difference was not significant in the multivariate analysis.
Finally, the small meal attracted a relevant target group, as small meal purchases were positively related to being female and to body mass index (the latter was borderline significant).
Moreover, patients presenting with multicentric disease at the time of diagnosis exhibited a borderline significant association with a higher risk of developing distant progression at the time of first progression.
In low-income, pathogen- and fecal contamination-rich, urban settings where sanitary conditions are poor, our study suggests better sanitary conditions measured via a sanitary survey may be associated with lower measures of environmental fecal contamination relative to poorer scores, though the absolute difference in contamination between poor and better sanitary conditions is minor and the association we found was borderline significant.
Discussion We found systematic differences between the test and retest session for three of the four motion parameters in the horizontal plane and in two of the four motion parameters in the frontal plane with one further parameter showing borderline significant differences between the two sessions.
By chi-squared analysis, the modification state at H3R2, H3T3 and H3K4 had a significant impact on binding, while the modification state at H3T6 was borderline significant.
intermedia and only one (Posse × Ilhéus) has a borderline significant value in L. whitmani .
Compared to recent GWA studies (see below), these studies were all based on small clinical samples (hundreds of individuals) with variable reporting practices and borderline significant results, compared to tens of thousands of individuals, harmonized genotyping platforms and protocols and stringent significance levels used in recent GWA studies.
Results were significant or borderline significant when the follow-up period was divided into early and late follow-up (Figure 6 ).
We also observed a moderate increase in the risk of colon cancer (1.36, 1.00–1.85) and a borderline significant increase in stomach cancer (1.23, 0.98–1.54).
Using WQS regression as a supervised strategy for characterising the mixture effect of the EDCs, and more specifically, in a stratified interaction model, we were able to detect at least a borderline significant positive (adverse) association for girls.
One meta-analysis 37 showed significant effects of exercise on depression and borderline significant effects on anxiety, while another meta-analysis 39 reported results from individual studies demonstrating non-significant effects on anxiety, distress, and self-esteem during breast cancer treatment.
Simple retrospective logistic regression analysis showed that the mid-follicular exogenous concentrations of human chorionic gonadotrophin (hCG) ( p = 0.027), provided by the HP-hMG preparation, and female age ( p = 0.009) were significantly associated with live-birth rate, while the mid-follicular progesterone concentration ( p = 0.075), the estradiol concentration on last stimulation day ( p = 0.075) and number of embryos transferred ( p = 0.071) were borderline significant.
We consider p -values below .05 as significant and p -values below .10 as borderline significant considering the relatively small amount of daily measurements ( Parker et al., 2011 ).
In the crude model, higher EDIP tertiles showed a borderline significant association with PCOS (OR: 2.01; 95% CI: 1.01–4.01; P -trend = 0.04), but this association attenuated after multivariable adjustment, including age, BMI, energy intake, physical activity, educational level, marriage status, parity, employment status, household income, history of diabetes mellitus, and hypothyroidism (OR: 1.50; 95% CI: 0.56–4.00; P -trend = 0.13).
Conclusion We find a significant association in the sequence data between the 8q24 region and oral cleft using our dimension reduction approach and a borderline significant association using the summary-statistic based approach.
Differences were considered as ‘not significant’ with (adjusted) p -values > 0.1, as ‘borderline significant’ (#) with (adjusted) p -values between 0.05 and 0.1, as ‘significant’ (*) with (adjusted) p -values between 0.01 and 0.05, as ‘highly significant’ (**) with (adjusted) p -values between 0.001 and 0.01, as ‘very highly significant’ (***) with (adjusted) p -values between 0.0001 and 0.001 and as ‘extremely significant’ (****) with (adjusted) p -values < 0.0001.
In women, borderline significant and significant positive associations were observed for height and risk of overall colon and rectal cancer, respectively.