Overexpression of wild-type WDR34 or WDR60 in the corresponding mutant cell lines partially rescued the delayed/impaired Golgi recovery after monensin treatment, with WDR60p.Ala911Val and WDR34p.Gly394Ser mutant clones displaying statistically significant recovery while clearly visible improvement of the golgi phenotype in WDR34p.Arg183Trp mutant cells did not quite reach statistical significance (Fig. 5J–M ).
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p=0.063
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22 Lastly, the analysis of non-PCa mortality favored iADT over cADT as a trend, though it did not quite reach statistical significance. 22 Though iADT is typically not initiated at the start of PCa treatment, it is typically considered appropriate to be deployed 9–12 months into treatment of traditional ADT or until PSA nadir has been reached, ideally reaching PSA < 0.1 ng/mL.
Migraine was associated with a trend towards lower QoL (β = −3.1, p = 0.058), suggesting a possible additional burden that did not quite reach statistical significance.
At 12 months, the difference did not quite reach statistical significance (aOR 0.77, 95% CI 0.57–1.04) ( Figure 2 ).
However, this did not quite reach statistical significance and perhaps other factors (such as HE diet) may be stronger contributors to adipocyte differentiation and function.
5 g) that did not quite reach statistical significance when intracellular ATP levels were measured with an enzymatic-based kit (Fig. 5 h).
Cerclage compared with no treatment Meta-analysis of the RCTs that have compared cervical cerclage against no treatment has shown a significant reduction in preterm births of 20% (average RR 0.80, 95% CI 0.69–0.95) and with a reduction in perinatal deaths although this difference did not quite reach statistical significance (RR 0.78; 95% CI 0.61–1.00) ( 13 ).
Second, while the topology of the two baselines (V1/V2 and FEF sessions) was almost identical (see new Figure 2—figure supplement 2 ), anticorrelations between V1/V2 and FEF in the FEF baseline did not quite reach statistical significance.
The variables that did not quite reach statistical significance included the Maximum Deviation, Maximum Nominal, and Percentage Away values, and thus were removed from further analyses.
A large prospective study found an elevated risk that did not quite reach statistical significance, but found a strong dose–response relationship with total years of exposure. 1 Two studies found no significant association, 1 2 although one found a suggestion of elevated risk among the very highly exposed. 2 We examine here the association of ALS mortality with job-related formaldehyde exposure in the National Longitudinal Mortality Study (NLMS), a US-representative cohort with occupation data collected prospectively.
( 2021 ) also found some preliminary evidence for debriefing when delivered to homogenous groups, but note that these findings did not quite reach statistical significance.
The levels of another adipogenic transcription factor PPAR gamma was also evaluated, which was consistently higher but did not quite reach statistical significance in ING3 and EPDR1 targeted cells (Fig. 3d ).
HEK293a-Shh cells treated with Hhat-#2 siRNA co-cultured with C3H10T1/2 cells (ratio 1∶2) for 2 days during day 2–4 of KD, resulted in a C3H10T1/2 response decrease of 32±10% compared to non-targeting siRNA, but this did not quite reach statistical significance.
Also, the size of the study group was relatively small and the true effect of RIPC might have been missed as there were multiple differences between the groups, which did not quite reach statistical significance.
There was a trend for the propofol-lesion group to have slightly more unintended damage to ventral hippocampus, but this did not quite reach statistical significance and was a very small difference (less than 3%).
The largest benefit with SFC was observed in cluster 1, but the difference in RR between clusters 1 and 2 did not quite reach statistical significance.
The use of aspirin appeared to be protective also in male carriers of the haplotype GC, although it did not quite reach statistical significance (OR=0.69, CI: 0.45–1.05).
Additionally, our relatively small sample size meant that certain differences between groups in specific outcomes (such as length of ICU admission), remained as trends that did not quite reach statistical significance.
Author Response: Our apologies as we incorrectly reported our changes in ultrasound muscle thickness as we observed a significant main effect for mid-thigh muscle thickness to increase (p = 0.04) while vastus lateralis (p = 0.12) did not quite reach statistical significance.
Interestingly, in contrast to our observations for RhoA, RhoB siRNA-treated cells had reduced levels of active RhoC in serum starved HUVECs, although this did not quite reach statistical significance (Figure 4B ).
Area power was reduced from 5.5 (IQ range 3.6–110.5) μV 2 to 1.4 (IQ range 1.0–36.6) μV 2 ( P =0.068, n =4) by this drug; however, this reduction did not quite reach statistical significance, possibly due to the range of ongoing area powers observed.
Differential gene expression analysis revealed an upregulation of Hoxa2 , Hoxa4 , and Hoxa5 in ATRX KO H3.3G34R relative to ATRX KO H3.3WT tumors though the difference did not quite reach statistical significance.
While the benefits of a post-operative stage improvement on long-term survival did not quite reach statistical significance, it was certainly trending that way and may reach significance as our sample size or follow-up duration increases.
This did not quite reach statistical significance.
However, a previous study of the CP phenotype ( 18 ) noted trends toward higher cardiac outputs and heart rates in CP that did not quite reach statistical significance.