However, the difference did not reach statistical significance at our adjusted alpha [ Z = 2.07, p = .038, two-tailed].
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“did not reach statistical significance”
In the literature
It should be noted that in a randomized Phase III study of axitinib in treatment-naïve patients with mRCC (one-quarter of whom were Asian), the difference in the primary endpoint of PFS between axitinib and sorafenib did not reach statistical significance in the overall population (median PFS: 10.1 vs. 6.5 months; hazard ratio 0.77 [95% CI: 0.56–1.05]; one-sided P = 0.038), but median PFS was significantly longer with axitinib than sorafenib in patients with ECOG PS 0 (13.7 vs. 6.6 months; hazard ratio 0.64 [95% CI: 0.42–0.99]; one-sided P = 0.022) ( 21 ).
Enrichment for hypermutators among patients who were heterozygous and homozygous for the deletion allele was also seen in bladder carcinoma, although this did not reach statistical significance (p=0.038, Bonferroni corrected p=0.452, Table 2 ).
Although daily reduction in body weight in T 1 AM treated mice did not reach statistical significance during the 8 days of treatment, weight loss was significantly greater than in sham mice at day 9 (−8.2 %; p=0.038 for the first study, and −8.6%; p<0.05 in the second study).
Sydney MAS was nominally significant (OR = 0.81, p = 0.038) whilst the other replication cohorts did not reach statistical significance but were generally in similar directions to the UKBB results.
For mean reticulocyte volume ( n = 176 SNPs), the primary IVW estimate did not reach statistical significance; nevertheless, the pleiotropy-robust MR-Egger analysis detected a significant protective association (OR: 0.9985; 95% CI: 0.9972–0.9999; p = 0.038), collectively reinforcing the potential involvement of erythroid traits in MS pathogenesis.
Although the analysis of relapse-free survival (RFS) in patients with HCC did not reach statistical significance, HCC patients with high TBK1 expression had significantly shorter OS (HR=1.800, P =0.038) ( Figure 2A ).
The patency rates for fistula failures presenting with stenosis were slightly better than those presenting with thrombosis, but they did not reach statistical significance (67% vs. 52% at 12 months; P = 0.038).
The percentage of patients aged > 65 years in the NSCS group (32.4%) was greater than those in the FS ≥ 1 (16.3%) and 0 ≤ FS < 1 (10.5%) groups, although the difference between the FS ≥ 1 and NSCS groups did not reach statistical significance ( P = 0.038).
A trend towards significant differences was found between these two groups on the lack of feeling ill on the AMDP, however this result did not reach statistical significance after a correction for the number of tests that were performed ( t = -.2.11, df = 73, p ≤ 0.038).
∆CRVE increased during head-down bedrest, but did not reach statistical significance until HDT16 [8.23 μm (95% CI: 0.44–16.02; p = 0.038) when compared to BCD-2. ∆CRVE returned to zero during the recovery (R0 and R8).
did not reach statistical significancep = 0.0387
Although p-p38 levels were elevated at 5 minutes (p = 0.7519) and 1 hour (p = 0.1713), the values did not reach statistical significance until 24 hours (p = 0.0387).
In these analyses, the HRs for AD mortality in non-aspirin NSAIDs users remained decreased but did not reach statistical significance in adjusted Cox models (HR = 0.30, 95% CI = 0.10–0.94, p = 0.039, unadjusted Cox model; HR = 0.26, 95% CI = 0.10–1.10, p = 0.060, Model 1; and HR = 0.25, 95% CI = 0.10–1.03, p = 0.056, Model 2).
Overall, regional cortical AV‐1451 SUVrs were higher in patients with MS compared to controls, but this did not reach statistical significance in any of the regions except for the lingual gyrus ROI ( p = 0.039).
g ., UshA, FusA) differed in the range of 2–4 fold, but they did not reach statistical significance; TamB showed ~7.5 fold reduction in Δ tamA ( p = 0.039) (Figs 3A and S7B and S1 Table).
3.67%), the difference did not reach statistical significance ( p = 0.039).
Neonatal birth weight was numerically lower in the ICP group; however, after BMI adjustment, this difference did not reach statistical significance (unadjusted p = 0.039; BMI-adjusted p = 0.064).
Although the p -value for precision (0.098) did not reach statistical significance—likely due to limited sample size—the latency increase ( p = 0.0399, d = 1.43) was both statistically and practically significant.
Subgroup analysis stratified by treatment regimen revealed that the same cutoff value predicted a trend toward longer survival in patients receiving combination therapy; however, the results did not reach statistical significance for OS (PFS: p = 0.04, OS: p = 0.06).
Although patients admitted during the third lockdown showed lower mortality, this did not reach statistical significance ( p = 0.04; non-significant after Bonferroni's correction).
Compliance rates regarding vegetable intake were higher in the simultaneous group than in the control condition ( P =.07) although this did not reach statistical significance; and respondents in the sequential condition reported smoking more cigarettes than respondents in the control condition ( P =.04).
Adverse events and procedure times were lower in the FTRD ® group, although these differences did not reach statistical significance (4.44% vs. 15.5%, p = 0.04 and 25.6 ± 10.6 min vs. 76.7 ± 26.4 min, p ≤ 0.01).
The arterial pulse amplitude association on the other hand did not reach statistical significance with age among any participant groups (minimum P = 0.04 for the normal group).
1 B), whereas giving touch did not reach statistical significance ( R 2 = 0.03, F (1,118)= 4.31, Β = −0.18, SE B = 0.09, t = −2.07, p =0.04) (model 3) (Fig. 1 C).
Dabigatran 150 mg was found to have an increased rate of myocardial infarction (0.74%) when compared with warfarin (0.53%/year), although this effect did not reach statistical significance (RR 1.38, 95% CI 1–1.91, p=0.04).