However, in WT KRAS IHC‐positive samples we also observed difference between N cry and T2 ( p = 0.022) and a trend towards difference in staining intensity between the T1 and the T2; however, this did not reach statistical significance ( p = 0.050; Table 1 ).
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Paired t -tests on the individual classification outcomes revealed that the differences in recall (∆ = 0.008, p = 0.53), precision (∆ = 0.0252, p = 0.047), and accuracy (∆ = 0.008, p = 0.53) between GPT-4 and the supervised NLP did not reach statistical significance ( p < 0.05 across all tests) suggesting that the overall performance of GPT-4 and the supervised NLP model is statistically comparable (when GPT-4 is provided a curated master list).
Later age of symptom onset (70+ years) was associated with lower odds of genetic testing completion (OR 0.23; 95% CI 0.12–0.43; P < 0.001) compared to the reference group (10–19 years), while early symptom onset (0–9 years) showed a trend toward higher odds of genetic testing completion that approached but did not reach statistical significance (OR 1.53; 95% CI 1–2.37; P = 0.05).
Although downward trends with advancing age were observed for SOD1, SOD2, PRDX1, and SRXN1, these changes did not reach statistical significance, except for SOD2 in the 50–59 age group and SRXN1 in the 60–69 age group ( p < 0.05, Figure S2 ).
However, the paired 2-sided t tests comparing the mean scores before and after editing across all institutions showed that these decreases did not reach statistical significance at P <.05 (risk: P =.06; overall: P =.13).
Crucially, however, the analysis of variance revealed that the effects of the three tested factors—carbon source, nitrogen source, and inorganic salts—on the mycelial growth rate did not reach statistical significance at the p < 0.05 level.
For stage III disease, the difference in DFS did not reach statistical significance ( p = 0.050) [ 46 ].
The between-group difference in Nesfatin-1 levels at week 12 approached but did not reach statistical significance ( P = 0.050).
Notably, there was a trend towards a higher rate of chorioamnionitis in the ADHD group that did not reach statistical significance ( p = 0.05).
In contrast, the effect of different-model training did not reach statistical significance ( g = −0.37, 95%CI: −0.74 to −0.00; 95%PI: −1.18 to 0.44; p = 0.05).
Regions that did not reach statistical significance ( p < 0.05) included the FOrb (0.19 ± 0.27), hypothalamus (0.15 ± 0.45), and amygdala (0.18 ± 0.48).
Notably, while the overall classification improvement was significant (NRI 0.675, P <.001), it was primarily driven by the accurate down-classification of nonevents (NRI for nonevents 0.530, P <.001), whereas the reclassification for events did not reach statistical significance (NRI for events 0.144, P =.05).
We found that while all mice in the control group (4/4) developed detectable tumors by day 17 that progressed rapidly thereafter, tumors in the IGF-Trap-treated group were only detectable in 1/5 mice at that time, and the growth rate in the majority of treated mice was lower than in the control group, although the difference under these experimental conditions did not reach statistical significance (defined as P ≤ 0.05) ( Figure 3B ).
Subgroup analyses based on different follow-up duration showed no significant differences at less than 3 months (WMD = −0.19; 95% CI: −0.84 to 0.46; p = 0.57) and at 3 months it showed a borderline improvement favoring punctal plugs, though this did not reach statistical significance (WMD = 1.72; 95% CI: −0.04 to 3.48; p = 0.05).
examined CD25 expression in 88 pediatric ALK+ ALCL patients in a univariate analysis and found that patients with high CD25 ALK+ ALCL tended to have lower 5-year overall survival (OS) compared with those with low CD25 ALK+ ALCL; however, this difference did not reach statistical significance ( p = 0.05) [ 25 ].
Additionally, SDNN and SD2, which indicate overall sympathetic and parasympathetic activity, were lower in the T1DM group but did not reach statistical significance ( p < 0.05).
The rate of pulmonary embolism was 29 of 455 (6.4%) in bevacizumab-treated patients and 45 of 455 (9.9%) in patients without bevacizumab, representing a difference that did not reach statistical significance (OR, 0.62 [95% CI, 0.38-1.01]) ( P = .05) (eFigure 4 in Supplement 1 ).
The multivariate regression modeling indicated that higher BMI and poor compliance were potential factors that might influence eradication outcomes, although these factors did not reach statistical significance ( P = 0.05).
However, the adjusted hazard ratios (aHRs) for the comparison between the accelerated (Rabies+JE-Accelerated) and the conventional (Rabies+JE-Conventional) schedule did not reach statistical significance (p < 0.05), with aHRs of 1.34 (95% CI: 0.94–1.90, p = 0.1021) and 1.47 (95% CI: 0.98–2.22, p = 0.0620) in the FAS-2 and PPS-2, respectively ( Fig 4 and S2 Table ).
The difference did not reach statistical significance ( p < 0.05), but it does correlate with the observed higher resilience to freezing stress.
Inhalation of salbutamol at equimolar concentrations as salmeterol also reduced TNFα in lung homogenates and BALF 6 h after infection with NTHi although in lung homogenates the difference with vehicle did not reach statistical significance (figure 2B and 2C : p < 0.05 versus vehicle in BALF).
The difference in CD4 + T-cell counts between groups did not reach statistical significance (SMD = -38.90, 95% CI: -77.35 to -0.45; p = 0.05), with low heterogeneity (I2 = 28%).
Although similar negative interaction effects were observed in the anterior insula and pre-SMA, these did not reach statistical significance at p < .05 ( Table 4 ).
Intervention patients were 1.77 (CI 0.94, 3.34, p = 0.078) times more likely than controls to be abstinent (12 versus 8%), a difference that approached, but did not reach statistical significance, and surpassed controls on number of days quit (18.4 versus 12.2, p < .05) but not on number of quit attempts.
Across all three datasets, higher levels of the NFκB and AP-1 upregulated genes were generally associated with worse outcome although the outcome differences between the high/low dichotomized cases often did not reach statistical significance (p < 0.05).