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extremely significant

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extremely significantp < 0.0010.0× alphaqualified
The results of calculating the p-value show that: p 0.05, the difference is not significant (ns); 0.01p 0.05, the difference is significant (*); and 0.001p 0.01, the difference is extremely significant, the difference is very significant (**); 0.0001 < p < 0.001, the difference is extremely significant (***). 3.
extremely significantP < 0.0010.0× alphaqualified
GSEA performed to evaluate concordance in transcriptional profile between the n = 238 genes included in the commercially available endometrial receptivity array and the LH + 7 versus LH + 2 UF-EV comparison demonstrated an extremely significant and consistent enrichment, with a normalized enrichment score (NES)=9.38 ( P < 0.001) for transcripts up-regulated in LH + 7 in the commercial array and enriched in LH + 7 UF-EVs, and a NES = −5.40 ( P < 0.001) for transcripts down-regulated in LH + 7 in the commercial array and depleted in LH + 7 UF-EVs.
extremely significantp < 0.0010.0× alphaqualified
The distribution of methylation levels in DMRs indicated that the average methylation level of the liver was 0.43 to 0.62 during the neonatal and lactation periods, 0.56 to 0.65 during the adulthood and lactation periods, and 0.49 to 0.60 during neonatal and adulthood periods, with extremely significant differences ( p < 0.001).
extremely significantP < 0.0010.0× alphaqualified
japonensis exhibited an extremely significant ( P < 0.001) positive correlation with the following gut microbiota taxa: Epulopiscium , U114 , Bacteroides , Clostridium and Peptostreptococcaceae (0.8< r < 0.9); and a significant ( P < 0.05) correlation with Enterobacteriaceae , Micrococcaceae , Rummeliibacillus , Lysinibacillus boronitolerans , Veillonellaceae , Oxalobacteraceae , Aeromonadaceae (negative), Marinibacillus and Chitinilyticum (0.4< r < 0.7).
extremely significantP < 0.0010.0× alphaqualified
The best effective group was a combination of curcumin 50 mg/kg with piperine 20 mg/kg which showed extremely significant ( P < 0.001) decrease and increase in ECG and serum biomarker level, respectively, and moderate significant ( P < 0.01) decrease in lipid profile, antioxidant levels, and histopathological score, compared to curcumin alone-treated group.