“highly significant”

For TPC, the quadratic model was highly significant ( p < 0.001 ), with high explanatory power ( R 2 = 0.962 ; R 2 a d j = 0.952 ).

Through RSM optimization (highly significant ( p < 0.001)), the optimal SAEW cleaning parameters were determined as follows: cleaning time of 35 s, cleaning temperature of 78 °C, and available chlorine concentration (ACC) of 108 mg/L.

Adding these variables drastically optimized the model’s predictive power, explaining an additional 26% of the variance (ΔR 2 = 0.26) with a highly significant step improvement (ΔF = 66.57, p < 0.001; overall model F = 49.97, p < 0.001).

* indicates significant differences (p < 0.05), ** indicates very significant differences (p < 0.01) and *** indicates highly significant differences (p < 0.001).

As expected, cue presented had a highly significant effect on response (LRT = 4958.2, p < 0.001); ‘stay’ responses being highest for the positive tone, lowest for the negative tone and intermediate for the ambiguous tone (Fig. 3 ).

A highly significant (***p ≤ 0.001) decrease of DOCK8 expression to 63% (±28.5% standard deviation (SD)) in ERU compared to healthy controls (100% ± 38.3% SD) was detected by western blot (Fig. 3A,B ).

• Estrogenic and Anti-Estrogenic study shows the highly significant value show increase in the uterine weight (410.67 ± 09.09 a ) mg/100 g b.wt.) and uterine contents was observed in estrogen treated group (P < 0.001) ( Table 6 ).

The PERMANOVA (with 999 permutations) revealed highly significant differences in microbial community composition across all groups ( p = 0.001), indicating that the experimental interventions collectively exerted a substantial impact on the gut microbiota architecture.

When analyzed separately in univariable logistic regression models, maximum PaCO 2 as well as lowest pH showed highly significant associations with poor neurological outcome (OR 1.17, 95% CI 1.06–1.28; P < 0.001 and 0.03, 95% CI 0.01–0.09; P < 0.001, respectively).

The difference in measured burst pressures when comparing the individual groups was also highly significant ( p < 0.001).

We computed a 3 × 2 repeated-measures ANOVA with factors ROUND(third-to-last, second-to-last, last) and AHA(aha, no aha) to compare mean FoW ratings, and found a highly significant main effect for ROUND [ F (2,52) = 132.27, p < 0.001, ε G-G =0.845, η p 2 =0.836, power G-G =1.0], no main effect of AHA [ F (1,26) = 1.05, p = 0.315, η p 2 = 0.039, power = 0.167], and a highly significant interaction [ F (2,52) = 15.63, p < 0.001, ε G-G =0.642, η p 2 =0.375, power G-G =0.988].

Behavioral EI had a highly significant relationship (β = 0.64, p < 0.001, n = 100) with perceived leadership effectiveness and no relationship with engagement ( Miller, 2014 ).

The RA + group had a highly significant occurrence of total day 3 AKI (74.1% vs 10.6%) and severe AKI on day 3 (60.6% vs 4.2%), based on KDIGO stage 2 and 3 ( P < .001).

Statistical comparison using McNemar test confirmed that the improvement in sensitivity achieved by the Mask R-CNN over the baseline U-Net was highly significant ( P < .001). 3.3.

The following final regression Equation (1) for production of total minor ginsenosides ( Y 9 ) was obtained in terms of coded factors: Y = 92.8 − 2.16 X 1 + 5.82 X 2 + 2.46 X 3 − 9.79 X 1 X 2 + 3.45 X 1 X 3 − 0.88 X 2 X 3 − 26.25 X 1 2 − 46.02 X 2 2 − 17.31 X 3 2 (1) The ANOVA results ( Table 3 ) showed that the total model for production of the minor ginsenosides ( Y 1 – Y 9 ) was highly significant, with a p value of <0.001, while the lack of fit is not significant relative to the pure error, with a p value of >0.05.

3.3 Genetic structure Moderate but highly significant genetic differentiation ( F ST = 0.090, p < .001) was detected across the whole turbot distribution using the 755 SNP panel, mostly attributable to divergence between the more isolated areas (Black Sea and the Adriatic Sea) and the Atlantic Ocean and the Baltic Sea (Table 3 and Table S1 ).

Effects of different IRE electric field parameters on the viability, apoptosis and necrosis of vascular endothelial cells At fixed 100 μs pulse width, 40 pulses, and electric field strengths of 200–800 V/cm, HUVEC cell viability showed a highly significant dose-dependent decrease (P < 0.001) ( Figure 1A ), with viability of 64.5% ± 3.2% in the 200 V/cm group, 21.8% ± 2.1% in the 400 V/cm group, 13.6% ± 1.5% in the 600 V/cm group, and 1.8% ± 0.7% in the 800 V/cm group 1.8% ± 0.7%, and the difference between 200 V/cm and the remaining groups was highly significant (P < 0.001).

Heart Rate Linear mixed model analysis demonstrated a highly significant main effect of Timepoint on heart rate (F(3, 84) = 4973.270, p < 0.001, η 2 = 0.994), indicating a substantial increase in HR during the TRAINING phase, followed by a return toward baseline values at POST 24 h ( Figure 6 ).

The strength of this correlation was 0.732 which is statistically highly significant ( P value < 0.001).

PERMANOVA confirmed highly significant differences in taxonomic composition between the Henan and Hebei provinces ( p < 0.001, Figure 3a , Table S3 ).

Highly significant positive correlations between the essential elements Cu and Zn were consistently found across all three matrices: diaphragm (ρ = 0.5469, p < 0.001), liver (ρ = 0.4251, p < 0.001), and testicles (ρ = 0.7564, p < 0.001).

Accordingly, the effect of experimental group on the repeated measure of visit rate over 1 h time periods is highly significant (F (2,13892) = 9.87, p < 0.001).

There was a highly significant positive correlation between the measured area of ROI and lesion sizes (r = 0.806; P < .001) (Table 5 ).

On all three tested Castanopsis species, Kruskal-Wallis tests revealed highly significant differences in lesion length among the three groups (CK, BZ-FL-1, BZ-FL-3) ( C. carlesii : χ 2 (2) = 22.388, p < 0.001; C. faberi : χ 2 (2) = 19.631, p < 0.001; C. hystrix : χ 2 (2) = 21.805, p < 0.001).

All the models were highly significant ( p -value < 0.001), displaying a non-significant lack-of-fit ( p -value > 0.05) that indicated a good fit.